Chloralum Hydratum

Hydrate of Chloral C^HGl^ 0+H^ 0.

Discovered in 1832, by Lieblg.

Proved by W. Eggert, S. Swan, D. A. Babcock, etc. See Encyclopedia, v. 3.

Poisoning, by E. W. Berridge, N. Y. J. H., v. 2, p. 307.

" Prepared by passing a stream of chlorine through absolute alcohol, until it comes over unchanged. The thick fluid remaining behind is chloral. The simple addition of water converts chloral into its hydrate."

The first therapeutic application of this substance was made by O. Liebreich, of Berlin, who conceived that the transformation of chloral into chloroform might be expected when it reached the blood of a living animal. On coming into contact with its alkalis the chloral would separate into chloroform and formicic acid.

W. W. Keen, of Philadelphia, has made use of chloral as an antiseptic and deodorant in the dissecting room and in surgical practice.

CiiiNiCAii Authorities Melancholia and headache, J. H. Sherman, X.

E. M. G., V. 9, p. 412; Mania-a-potu, J.

C. Wilson, K E. M. G., v. 6, p. 160;

Ophthal- mia, Dyce Brown (2 cases), B. J. H., v. 32, p. 509; Conjunctivitis, (2 cases), Dyce Brown, B.

J. H., v. 32, p. 510 ; Conjunctivitis and Keratitis on left eye, Dyce Brown, B. J.

H., v. 32, p. 510 ; Toothache from decayed teeth (2 cases) Excelsior, N. A. J.

H., V. 23, p. 123; Odontalgia traumatica, Hale, N. E. M.

G., 1872; Colic of children, Hale, Symptomatology; Ascites, Bishop, Med. Inv., v. 11, p. 139 ;

Enuresis, Oehme, Kaue's Path., p. 691, also El. Crit. Med., Aug., 1874; Incontinence of urine (5 cases), E.

Vechetti, Horn. Kev., v. 18, p. 571, Leonardi, N. A. J.

H., v. 22, p. 408 ; Chordee, E. M. Hale, N.

A. J. H., 1870, p. 244; Dysmenorrhcea, Excelsior, N.

A. J. H., V. 23, p. 122; Pruritus vulvce during pregnancy, Dyce Brown ;

Inefficient labor pains. Excelsior, N. A. J.

H., v. 23, p. 123; Puerperal convidsions, F. A. Lord, U.

S. M. & S. J., V. 7, p. 360 ; Puerperal eclampsia, D.

Baumetz (from Lancet), Horn. Kev., V. 17, p. 310; Infantile tetanus. Hale (see Sympt.) ;

Typhoid pneumonia with sleeplessness, J. C. Neilson, N. E.

M. G., v. 6, p. 161; Palpitation during phthisis, Swan, Am. Ob., v. 10, p. 136 ;

Foul-smelling foot sweats, Ortega, N. A. J. H., v. 26, p. 412 ;

Violent hysterical fit, J. C. Neilson, N. E.

M. G., v. 6, p. 161 ; Chorea, Strange, N. A.

J. H., V. 23, p. 123 ; Chorea during pregnancy, J. Russell, N.

A. J. H., v. 23, p. 123 ; Idiopathic tetanus, M.

L. Sircar, Calcutta Journ., v. 3, p. 389 ; Ana- sarca from valvular disease of heart. Swan, A.

H. Obs., 1873, p. 135 ; Preventive to sea-sickness, Geraldis, A. O. ;

J. C. O. Will, Horn.

Rev., v. 16, p. 561, Ober, N. A. J. H., V. 24, p. 567 ;

Urticaria and Pruritus, Dyce Brown, B. J. H., v. 32, p. 512; Urticaria (2 cases), Dyce Brown ;

J. C. Burnett, H. M., v. 13, p. 56 (2 cases) ;

A. C. Clifton, H. R., v. 21, p. 526.

^ Mind. Comatose for days, ending in cerebral congestion. Melancholia, idiocy and insanity.

vol.. IV. — 6.

CHLORALUM. 82

Fixed despair of recovery ; believes he will give his imagi- nary disease (syphilis) to others.

Confusion of mind, inability to concentrate thoughts, impaired memory ; could not keep the thread of sermon.

I Mental diseases, and general paralysis of patients suffer- ing from mental diseases.

I I Constantly hears voices.

■Sleeplessness at night, with restless irritability; headache, confusion in head; melancholy; inclined to wander and hide herself, avoiding shrewdly the vigilance of her friends ; would then return, unable to give any ac- count of where she had been.

I He walks hurriedly up and down the room, talking to himself in an excited manner, and holding conversation with imaginary beings. ^Acute mania induced by se- vere mental excitement.

Jumps out of bed with fear, cold sweat, screams as if in mortal terror ; night terrors of children.

Gorgeous visions of arches, tapestry and colors, pass before the eyes when shut, or open in the dark.

I ! Wild delirium changing to a busy delirium ; visions of fantastic objects ; a great deal of fever; pulse 120 most of the time. ^Delirium tremens.

Delirious, she hurls a hot water bottle at an imaginary figure at foot of bed.

I I Boisterous mania.

': Delirium of typhus.

I I Delirium tremens, when brain is congested.

I I Puerperal mania, with sleeplessness.

Hydrophobia. ^ Inner Head, i ' Cephalalgia.

I Hard, full, pressing pains in head continuing a long time without relief. ^Dysmenorrhoea.

Dull, heavy, aching pain in forehead and occiput all day, < by motion.

Severe pain in frontal region over supraorbital ridge, which nothing relieves, < by motion.

Headache in forehead, extending to occiput.

Headache over both eyes, running down into eyes, 1. side worse, with feeling as if eyes were constricted.

I Neuralgia of temporal region.

Feeling as if a hot band was drawn across forehead from temple to temple directly over eyes, with sensation of a burning ring around each eye.

Dull, heavy headache in occiput and forehead over eyes; a feeling of weight and soreness, which seems wholly within cranium; < by moving about and lying down, slightly > by going into open air.

83 CHLORALUM.

1 I Cerebro-spinal congestion.

I I Cerebral congestion following a condition of extraordi- nary depression of nervous system.

Congestion of brain with some mental excitement. * Outer Head, l Great heaviness of head; cannot lift it.

Erythema of head and neck. ^ Sight and Eyes. Retinal hypersesthesia.

Sensitive to light.

Colors are unusually bright.

Objects look white; color blindness.

Dark spots before the eyes.

I Dimness of sight.

Eyesight weak, dim, globe congested, lids swollen and sometimes partially paralyzed.

Peculiar dimness or weakness of sight; must read with one eye at a time — for a minute or two with each ; if one eye was used longer than a minute, the words and letters became blurred and indistinct.

If one eye only is used until objects fade, the other sees objects plainly for awhile.

Can see small objects only for a few moments, they fade away.

Eyeballs feel too large.

■ Burning in eyes and lids.

Sensation of a burning ring around each eye.

Feeling as if eyes were constricted, with headache.

Sharp pain in the eyeballs.

Redness and watering of eyes.

Watery eyes, especially when looking at anything.

■ Conjunctiva congested.

■ Eyes injected and bloodshot, constantly watering.

■ I Face and eyelids so swollen that he could hardly see.

^Urticaria. Conjunctivae injected, face has a puffed and swollen appear- ance, especially below eyes.

■ Ocular and palpebral conjunctiva of 1. eye much injected,

with considerable pain ; a small ulcer on cornea reduced to size of a pin point. ■Right eye much injected, with great pain; 1. eye also slightly injected. ^Conjunctivitis.

■ Conjunctivitis of r. eye, which is very red and painful,

deepcut ulcer in centre of cornea ; of a strumous family.

■ Conjunctivitis and corneitis on 1. eye; cornea is diru; in

r. eye considerable redness of palpebral and ocular con- junctiva at one point ; great photophobia.

■ Conjunctivitis of both eyes; small ulcer on .1. cornea;

feeling of sand in eyes, but almost no photoj)hobia ; is a very strumous patient.

CHLORALUM. 84

B Catarrhal ophthalmia; there are one or two phlyctenee on r. eye, at edge of cornea ; severe circumorbital pain and photophobia.

■ Intense itching of inner canthi and edges of lids. I Puffy swelling of lids.

Eyelids feel so heavy he can hardly lift them. Ptosis (in a man who took it for overtaxed mind). ^ Hearing and Ears. Great sensitiveness to noise. ^ Upper Face. Dark scarlet flushing and heat of head and face, from roots of hair to ramus of lower jaw, neck and chest, including eyes, persistent under pressure; blotchy in places.

I I Face red and swollen. ^Urticaria. Face erysipelatous ; swollen so he could not see. i Neuralgia of infraorbital branch of fifth nerve. ^ Lower Face. Lips covered with sordes and dried blood. Swelling of parotid and submaxillary glands.

I I Blueness of lips. ^° Teeth and Gums, l l Neuralgia from decayed teeth.

I I Odontalgia traumatica from pressure of filling ; pain

unbearable; <C when lying down. I Excruciating toothache from decayed teeth, with neural- gic affection of jaw.

■ Neuralgia of inferior dental branch of fifth nerve. " Taste and Tongue. Deeply coated tongue.

A black streak along centre of tongue as though ink had been rubbed over it. ^^ Inner Mouth. Lips, mouth and fauces red and raw, gums

spongy, tongue blistered and ulcerated. ^^ Throat. Spasm of throat.

Partial paralysis of oesophagus.

I I She could not utter a syllable and swallowed with diffi- culty. ^* Appetite, Thirst. Loss of appetite.

Thirst. ^^ Vomiting, l Vomiting and nervous irritability during

course of cerebro-spinal meningitis. ^^ Scrobiculum and Stomach, i i Feebleness of stomach. 1 Sense of sinking and oppression at pit of stomach. Sense of emptiness shortly after eating. ^^ Hypochondria, l l Hepatic and renal colic, dependent on passage of calculus. I Gall stones. Atrophy of liver. ^^ Abdomen. ■ Severe colic of children, when the pain threat- ens to cause spasms. ■Ascites attendant upon supposed case of phthisis pulmo- nalis.

85 . CHLORALUM.

^ Stool and Rectum. Soft, lumpy, strong smelling stools twice a clay, and frequent passage of fetid flatus. I I Diarrhoea at night with excessive nervous excitement.

^Dentition. Cholera without vomiting or diarrhoea. ^^ Urinary Organs. ■ i Nephritic and hepatic colic dependent upon passage of calculus. I 1 Increases urine when given for anasarca from heart disease.

■ Urinated copiously in bed without knowing it.

I Nocturnal incontinence of urine ; in * children in latter

part of night, even if they have urinated during night

and drank no water. Frequent and profuse urination of dark amber color, clear

and without odor. ^^ Male Sexual Organs. Loss of sexual power; no desire or

erections; impotence. iChordee during gonorrhoea. ^ Female Sexual Organs. If taken immediately before onset

of catamenial discharge, it entirely checks it. I I Menses irregular. ^Urticaria.

■ Severe spasmodic pains in and about the uterus. ^Dys-

menorrhoea. ■Pains very severe and labor-like. ^Dysmenorrhoea. I I Thick, yellow leucorrhoea, tinged sometimes with a

little blood. ^Urticaria. ^ Pregnany, Parturition, Lactation. ■ Troublesome pruritus

during pregnancy.

■ Tedious labor lasting over eighteen hours; nervous, irri-

table, hysterical condition; the pains which are appar- ently normal and forcible have no effect on the uterus. : Severe labor pains. I I Puerperal convulsions. 1 I Severe case of chorea during pregnancy. ^ Voice and Larynx. Trachea and Bronchia. • Bronchitis. ^ Respiration. I Gasping breathing and confusion of thought; sinking at stomach.

■ Great dyspnoea, a sense of suffocation; oppression at base

of chest (in front), with urgent thirst. I I Slow resjDiration, with imperceptible pulse. Laborious respiration, occasional deep inspiration, with a

sighing expiration. Wheezing respiration. Stertorous breathing, with loud snoring during sleep, in

any position. When lying on back, the inspiration was through the

nose, while the ex23iration was blown from the lips as

in apoplexy.

CHLORALUM. . 86

■Asthma; the nightly paroxysms are very severe; he is bent forwards^ can hardly catch his breath. ^ Cough. I I Hard, difficult cough. ^Chest affections.

Spasmodic cough accompanying last stage of phthisis.

I I Labored cough of bronchitis and phthisis.

Whooping cough.

Croup. ^^ Inner Chest and Lungs. Pulmonary congestion.

I I Constriction at base of chest, with dyspnoea, in organic heart affections.

Sense of weight on chest in region of sternum at night, causing expiration to be easier than inspiration.

Singular sensation of fulness of chest, not as if it w^as filled up as a person experiences after a meal, but rather as if all the tissues were hypertrophied, producing an inde- scribable sense of tightness and pressure on the lungs, causing very labored breathing and redness of face.

I I Great dyspnoea with labored action of lungs. ^Dropsy.

I Congestive bronchitis with spitting of blood; painful and audible breathing.

I 1 Severe attacks of typhoid pneumonia ; unable to sleep from nervous irritation, dyspncea and cough. ^ Heart, Pulse and Circulation. Heart's action regular but with increased frequency and diminished force.

■ Increased action of heart and oppressed respiration.

I I Violent palpitation with dyspnoea. ^Hypertrophy with dilatation.

I I Palpitations so violent that they can be heard ; great difficulty of respiration, patient requires constant fan- ning. ^Phthisis.

Palpitation accompanies hypersemic condition of skin ; < from wine, beer or spirits.

Heart dilated or weakened, with peculiar fulness and lightness of chest and sense of emptiness in stomach.

i Angina pectoris.

Valvular disease of heart with anasarca.

I I Diminution of heart's action in organic affections, with dyspnoea and constriction of base of chest.

I I Heart beats become feeble, irregular, very rapid.

I I Heart feeble, pulse weak ; could not lie down ; general anasarca.

Cardiac neurosis.

I I Threatened paralysis of heart. ^Pericarditis.

I 1 Pulse frequent, irregular, weak, intermittent, heart act- ing regularly but with increased frequency and dimin- ished force.

Weak, irritable pulse, threatening paralysis of heart.

Imperceptible pulse, cold extremities, slow respiration.

Pulse 88.

87 CHLORALUM.

^^ Neck and Back. Erj^thema of head and neck.

A purple discolored band, two inches wide, along each side

of vertebral column. I I Large patches of redness with urticarious wheals about

neck, trunk and extremities. At base of skin large greenish spots. ^^ Upper Limbs. Upon red surface of 1. arm a piass of minute points of a deeper red. Left arm swollen and indurated.

Erythematous inflammation, desquamation and ulceration around border of nails; pain, great sensibility to touch. ^ Lower Limbs. Sensation and motion paralyzed in both legs. Foul smelling foot sweats. ^ Limbs in General. Wandering rheumatoid pains.

I I Cold extremities, with blueness of lips, slow respiration,

imperceptible pulse.

I I Large red patches on arms and legs, exactly like nettle rash, in large raised wheals, with intense irritative itching.

^ Rest. Position. Motion, i ' Limbs extended, head low, appearance of impending death.

Lies in a state resembling catalepsy ; hysteria.

Lying down : < headache ; < toothache ; impossible on account of weak action of heart.

Lying on back : inspiration through nose, expiration, through lips.

In any position : stertorous breathing.

Bent forward : in asthma.

Could neither lie nor stand ; chorea.

< pain in forehead and occiput; pain over supra- orbital ridge. 36 jferygg^ Lassitude.

Unaccountably depressed and very weak, especially in lower limbs, this weakness increasing until he is com- pelled to give up his daily walks from sheer inability to put one leg before the other.

I I Great muscular prostration, limbs extended, head low, appearance of impending death,

I I Tendency to weakness, feebleness of stomach, blue lips, cold extremities, slow respiration, imperceptible pulse.

I I Great exhaustion from sleeplessness. ^Acute rheuma- tism.

Extraordinary depression of nervous system, following cerebral congestion.

Great prostration, tendency to somnolence. I I Neuralgia.

I Violent hysterical fit; she lies in a state resembling cata- lepsy.

CHLOKALUM. 88

I 1 Nervous irritation; mania; hysteria; mania sL potu; epilepsy ; convulsions of children.

I I Chorea : patient could neither lie nor stand, the head, limbs and body being in constant motion and each muscle apparently partaking of irregular action.

I I Long continued and obstinate chorea.

I I Intense chorea, where constancy and severity of spas- modic movements threaten life of patient.

I I Trismus and trismus nascentium.

I Traumatic tetanus and infantile tetanus.

I The whole body engaged in tetanic rigidity, fits coming on at very short intervals ; mouth can only be slightly opened; deglutition very difficult. ^Tetanus.

iSudden violent tetanic fit with lockjaw; weeping mood; sudden very violent pain in abdomen. ^Tetanus.

Motor and sensory paralysis of both legs. ^' Sleep. I I Insomnia arising from overfatigue, mental or physical.

During sleep, stertorous breathing with loud snoring in any position.

I Night terror, especially in teething children.

Horrible dreams with frightful visions, they scream and cry out, sit up in bed and cannot be quieted.

I I Wakes from disturbed rest, cries out and screams until perfectly exhausted and in danger of general convul- sion. ^Chorea. ^'^ Time. At night : sleeplessness ; terror of children ; diarrhoea with nervous excitement ; enuresis ; paroxysms of asthma ; sense of weight on chest, in region of sternum ; irritation of skin.

Latter part of night : incontinence of urine in children.

Towards evening : itching of chin, and front and back of neck. ^^ Temperature and Weather. Requires constant fanning ; palpitation and dyspnoea in phthisis.

High fever.

I I Fevers where cephalic symptoms do not contraindicate its use. *^ Attacks, Periodicity. Paroxysms : of asthma nightly.

Lasting over eighten hours : tedious labor.

All day : headache in forehead and occiput.

Continuing a long time : pains in head.

For days : comatose. ■*" Locality and Direction. Left: above and in eye, head- ache <; conjunctiva injected; eye slightly injected;

89 CHLORALUM.

conjunctivitis and keratitis ; small ulcer on cornea ; bad eruption on arm ; arm swollen and indurated.

Right: eye injected, painful ; conjunctivitis: ulcer on cor- nea; redness of palpebral and ocular conjunctiva; phlyctense on edge of cornea. ^ Sensations. As if a hat-band was drawn across forehead.

As if eyes were constricted.

As of a burning ring around each eye.

As if eyeballs were too large.

As of sand in eyes; sinking and oppression at pit of stomach ; as if tissues in chest were hypertrophied (ful- ness) ; on chin and neck like minute insects or hairs.

Sharp pain : in eyeballs.

Hard pains : in head.

Severe pain : in frontal region.

Neuralgia : of fifth nerve ; from decayed teeth ; from pressure of filling of jaw; of inferior dental branch of fifth nerve.

Rheumatoid wandering pains.

Stinging : over whole body.

Spasmodic pains : in and about uterus.

Colic : hepatic and renal ; of children.

Labor-like pains : in dysmenorrhoea.

Burning : in eyes and lids ; ring around each eye ; sting- ing over whole surface.

Aching pain : in forehead and occiput.

Dull pain : in forehead and occiput ; over eyes.

Full pains : in head.

Heavy pain : in forehead and occiput ; over eyes.

Pressing pains : in head.

Soreness : within cranium.

Pressure : on lungs.

Oppression : at base of chest in front.

Tightness : on lungs ; over whole surface.

Constriction : at base of chest.

Fulness : of chest.

Heaviness : of head ; of eyelids.

Weight : within cranium ; in chest in region of sternum.

Lightness : of chest.

Emptiness : in stomach shortly after eating.

Heat : of head ; of face ; all over body.

Itching : of inner canthi and edge of lids, of chin, and front of back and neck ; over whole body.

Hardness : over whole surface. ^' Tissues. I I Patient anaemic and emaciated. ^Chorea.

Acts primarily on ganglia of brain, then of spinal cord, finally on those of heart, so that paralysis of heart sets in.

CHLORALUM. 90

Causes cessation of cardiac movements, diminishes excita- bility of motor centres, of respiratory and abdominal muscles, and lessens irritability of vaso motor centres.

Produces first sleep, then more or less ansesthesia, and during both relaxation of muscles.

In muscular debility, fatty degeneration and dilatation, when there are evidences of nervous deficiency, as shown by irregularity or intermittency of action and palpitation of heart.

The temperature falls, with sinking of pulse and respira- tion.

I Destroys coagulability of the blood.

I I Hemorrhagic diathesis.

Typhoid cases with epistaxis ; haemoptysis ; hgematemesis.

Favors the production of hemorrhage and tends to reopen recently cicatrized ulcers of mucous membranes.

I I Anasarca.

I I Purpura hsemorrhagica.

Gangrene on places exposed to pressure, especially in patients laboring under mental diseases, the gangrene spreads in depth with an intact skin.

I I Rheumatism and gout.

Antiseptic dressing for wounds even when there is ery- sipelas.

Touch : sensitive around border of nails.

Pressure : does not alter scarlet flush on head and face ; erythema remains unchanged. *^ Skin. Hypersemia of skin < from smallest quantity of wine, beer or spirits, with distressing palpitation.

I An itchiness of chin and front and back of neck, coming on towards morning, sensation like minute insects or hairs.

Pruritus of whole skin and of mucous surfaces of upper outlets of body,

I I Violent stinging, itching sensation over whole body. d Urticaria.

Burning-stinging sensations, and a feeling of tightness and hardness over whole surface.

Intense irritation and itching of skin, preventing sleep at night.

Great irritation of skin with swelling of eyelids.

Marked cutaneous anaesthesia.

Bright, scarlet eruption on face, body and limbs.

She is much flushed, and there is present over the whole body a diffuse inflammatory redness closely resembling the smooth eruption of scarlatina.

91 CHLORALUM.

Bright red or bluish erythema over whole body, per- manent under pressure, mottled with livid patches and deep red spots.

■ Eruption on arms, legs and face and subsequently over

whole body in large blotches of different shapes, raised above the surface and of a deep red color ; these blotches gradually coalesce, till the whole skin is in a red and blotchy state, resembling measles.

■ Blotches of redness over legs and body in distinct wheals,

not much fever.

A mass of minute points or stigmata upon the red surface of 1. arm, of a much deeper red, permanent under pressure.

Eruption on arms and legs, exactly like nettle rash in large raised wheals, with intense, irritating itching, oedematous swelling of face, cheeks, eyelids, ears, com- ing on suddenly from a chill, not from heat.

1 I Wheals come on suddenl}^ from a chill, crops of them appearing many times a day; as long as she remains in the warmth is not troubled with them.

■ Rash "like the sting of a nettle," coming out every night,

and almost disappearing during the day; it is very

itchy, and after washing with soap and water becomes

painful, disturbing sleep at night. ■Urticarious eruption, which disappears by day and comes

out at night, with such itching as to keep child from

sleeping. Large greenish spots at base of spine.

■ Eruption rises in white blisters on being scratched, there

is great pruritus. ^Urticaria.

Nettle rash < night, compelling scratching until places bleed ; fever and restlessness.

Arms red and speckled, with threads of white dead epi- dermis partially separated from subjacent cutis.

General desquamation in round patches like blisters, from which serum had been absorbed, leaving skin beneath of a purple and in some places yellow color.

Purpura hsemorrhagica ; herpes circinatus.

■ ■Decubitus. ^Dropsy. ^Scarlatina. ^Erysipelas.

^'^ Stages of Life, Constitution. " Its action is more uncertain

in persons who are free livers and in those accustomed

to the use of alcohol." Children, incontinence of urine. Peter B., set. 6 months; already weaned; red blotches and

the remedy also caused passage of a round worm; tetanic

convulsions.

CHLORALUM— CHLOROFORMUM. 92

Jane W., set. 13; taken ill with headache, sickness and vomiting, which lasted three days, when an itching urticaria developed.

Girl, £et. 18, had a previous attack ; violent hysterical fit.

Mrs. S., set. 38 ; catarrhal ophthalmia.

Mrs. S., set. 38, and son, set. 8 ; urticaria.

German, set. 46 ; from having become wet ; urticaria.

1 Bellad., 1 1 Chlorof., I Gelsem., I Nux vom., I Opium.

\ It may be used where opium is contraindicated, in gen- eral, after operations.

Chloroform. CHCl

^ Mind. Difficult comprehension.

Excitement quickly subsiding into stupefaction, in which, however, the will of the individual is evidently active.

Great weakness of brain, with loss of memor}^, retarded power of comprehension and thinking, with frequent occurrence of confusion of intellect. ,

Weeping.

Low moaning.

I I Mania from intoxication (olfaction).

Delirium, sometimes quiet, sometimes violent.

Delirium tremens where excitement and violence pre- dominate. ^ Sensorium. Giddiness.

Seasickness.

93 CHLOROFORMUM.

iRajDid convulsive movements of muscles of face; whole face frightfully distorted. ^Arachnitis. ^ Lower Face. A slight stinging and burning in lips.

Involuntary stools of mucus and blood, with great tenesmus. ^^ Urinary Organs. Bladder irritable.

^^ Γυναικεία γεννητικά όργανα. Υστερικές καταστάσεις που οφείλονται σε ευερεθιστότητα και σπασμό του τραχήλου της μήτρας.

CHLOROFORMUM. 94

Νεύρωση των γεννητικών οργάνων.

Pain in dorsum of hand and joint of thumb. ^^ Lower Limbs. Desire to stretch the lower limbs.

95 CHLOROFORMUM.

which continues for about one minute and then passes off, without waking him from sleep. ^Arachnitis.

Spasms resembling hysteria, especially in females.

Tonic and clonic spasms.

I I Tetanic spasms. ^Typhus fever.

Trismus.

I I Convulsions.

■ Puerperal convulsions from uraemia or reflex irritation.

Entire inactivity of all the external sensibilities, so that even considerable injury to the nerves produce no reflex motion in the periphery.

Total cessation of motion and sensibility. ^ Sleep. Great sleepiness, yawning, and invincible lassitude.

Sleep commonly dreamless.

Comatose sleep. ^° Fever. A general feeling of warmth flowing through whole body.

I I Typhus fever, with tetanic spasms.

Typhus fever, with great prostration, delirium, subsultus, irregular respiration and nervous restlessness. *^ Sensations. As if fingers and toes were asleep ; as of warmth flowing through whole body.

Pain: in region of cardiac orifice of stomach; in abdomen; in back; in larynx; in region of 1. kidney; in dorsum of hand and joint of thumb; in region of r. sciatic nerve.

Stinging: in lips.

Burning: in lips.

Colic: biliary; abdominal; renal.

Rheumatic pain: about the joints. *" Skin. Skin cold, pale.

"It must not be used when there is softening of the brain; severe organic heart disease, with intermittent pulse; aneurisms of aorta; extreme weakness from hemor- rhages ; extreme ansemia, and great tendency to syncope."

" In drunkards the stage of excitement can not be over- come without grave danger to life."

" Use contraindicated : in fatty degeneration of heart ; in those addicted to the use of spirituous liquors; where there is albuminaria."

Clergyman, set. 58, who had suffered twenty-three years from gall stones.

CHLOROFORMUM— CHLORUM. 96

In narcosis from chloroform, small pieces of ice placed in rectum produce deep inspiration soon followed by natural breathing.

It antidotes: Strychnine.