Lycopus Virginicus

Bugle Weed. Labiatse.

This plant, sometimes called Virginia Hoarhound, grows in shady and wet places throughout the United States. The tincture is prepared from the fresh plant in flower.

Provings by Chandler (Hale's New Rem.), tincture and first dilution, Mor- rison (Mon. Horn. Eev., vol. 16, p. 737), tinctui-e and 200th dilution, three j^rov- ings ; produced considerable action upon the heart ; took sphygmographic tracings (Mon. Horn. Eev., vol. 18, p. 620).

Clinical Authorities Diabetes, Gerald, N. A. J.

H., vol. 27, p. 239; Eay, Hale's Therap., p. 406 ; Incipient phthisis, Hale, Hale's Therap., p. 402 ; Pal- pitation of heart, Chamberlain, Times Retros., vol. 3., p. 31 ;

Heart disease, Cum- mings, B. J. H., vol. 34, p. 388 ; Exophthalmus, Morrison, Hale's Therap., p. 404 ;

Cardiac irritability, Hale, Hale's Therap., pp. 403-4; Typho-malarial fever, Kent, Hom. Phys., vol. 4, p. 257; Verification of symptom 179 in Allen's Encyclopedia, Eeed, Trans.

Hom. Med. Soc. Pa., 1883, p. 306.

^ Mind. Increased mental and phj^sical activity in evening. I I Stupid, with lack of expression during menstrual flow. I I Mind wanders from one thing to another.

I I General wakefulness and morbid vigilance. Slight obtusion of intellect, with dull aching through sin- ci|)ut; increased power of concentration. ^ Sensorium. Vertigo ; tends to stagger to right. ^ Inner Head. Pressure in forehead, < in 1. portion.

Dull aching in sinciput, slight obtusion of intellect. Aching in frontal eminences, 1. to r., < left. I I Pain in forehead and temple, > by nausea. I Headaches : frontal then occipital ; over eyes and frontal eminences: pains aching, pressive, pressing out, con- gestive; often succeeded by labored heart and cardiac depression; accompanied by intellectual obtuseness. ^ Sight and Eyes.

Eyes feel weak, as if system was over- fatigued. Eyes feel full and heavy; pressing outward, with pressure

in front of head. Dull pain in 1. supraorbital region. Neuralgic pain in r. supraorbital region and 1. testicle. BProtrusion of eyes, with tumultuous action of heart; ex- onhthalmic goitre. ^Morbus Basedowii. ''' Teeth and Gums. Toothache in r. lower molars, then sub-

151 LYCOPUS VIRGINICUS.

acute pain, first in 1. then in r. frontal eminence, in r.

molar, then r. temple, then 1. molar, then 1. temple,

again to r. molar, then to loins, with frontal oppression.

^^ Throat. Rawness at back of palate, r. side, extending to left.

Burning in spot in soft palate, following headache. ^^ Hiccough, Belching, Nausea and Vomiting. Nausea from back of fauces, > by eructations that taste of tea and drug; succeeded by persistent giddiness while sit- ting, and staggering while walking. Nausea and faintness. " Scrobiculum and Stomach, i Circumscribed pain and com- pression in region of stomach. I 1 Indigestion, with pain and distress in epigastric region. I 1 Gastritis ; enteritis ; diarrhoea ; dysentery. ^^ Hypochondria. Lugging pain in spleen.

Tenderness in 1. hypochondrium. ^® Abdomen. Flatulence and rumbling.

I Aching in inguinal canal, < walking, > from upward pressure; with pain in testicles; bearing down as from hernia. ^^ Stool and Rectum. Severe colic, followed by profuse for- cible diarrhoea; stools shining, dark brown, offensive; tenesmus with first part of semi solid movements. Increased action of bowels, aggravated by diarrhoeic symp- toms; could have a passage at any time, but sphincter is under perfect control.

■ Diarrhoea in jaundice, from weakened heart.

I Diarrhoea with griping and rumbling. ^Phthisis.

■ Constipation lasting six or seven days, stools dry and cloglike.

'Protrusion of eyeballs, cardiac depression and palpitations, < ascending, from excitement, deep inspiration, or thinking of them; irregular and inter- mittent pulse, not corresponding to beat of heart; fron- tal and fronto-occipital headache, > by strong pressure; sense of constriction in larynx ; cough with slight, pale expectoration, wheezing and hot aching beneath r. scapula ; oppressed respiration, with sighing ; tremulous feeling in hands ; erratic rheumatoid pains, < toward sunset and during evening. ^Morbus Brightii. I Drinks large quantities of water; passes nine to eleven quarts of urine a day; fearful thirst, nothing but coldest water would satisfy ; very irritable unless spoken to very softly ; was not inclined to talk even to her own family. ^Diabetes.

■ Diabetes mellitus ; gallon or more daily of clear urine, of great density, containing sugar ; great thirst and emaciation.

LYCOPUS VIRGINICUS. 152

Tenderness in bladder.

Bladder feels distended when empty ; dull pain in 1. lum- bar region.

I Profuse flow of limpid, watery urine, especially when heart is most irritable.

I I Urine scanty, thick, muddy, oedema of feet.

1012 to 1021; cloudy; acid; contains mucus, epithelial cells and minute crystals, oxalate of lime, spermatozoa. ^^ Male Sexual Organs. Neuralgic pain in testicle, with supraorbital pain.

Acute aching in testicle while sitting, 1 p.m., or with occa- sional darting pains, changing to r. then to 1., after rising.

Acute pain in testes, from r. to 1., then both, recurring and lasting whole evening, with aching in inguinal canal.

I Sharp darting through 1. testicle.

■ Relieved pain in testicle, but had no influence on orchitis. ^ Female Sexual Organs. 1 1 Menorrhagia and metrorrhagia.

I I Menses: intermit for ten or twelve days; last from half hour to six hours.

I I Vagina very hot, os uteri engorged and swollen.

I I Puffing of parts on and around pubes and vulva, di- lated condition of vagina.

Expectoration pale, sweetish, unpleasant tasting, at times difficult, renewed same as cough.

■ Cough, with haemoptysis, feeble, quick, irregular action of

^Phthisis.

■ Febrile irritation; quick, weak pulse; occasional heemop-

tysis; dyspepsia; weakness; deposit of tuberculous mat- ter in apex of 1. lung; irritable action of heart, palpita- tion occurring from least exercise. ^Incipient phthisis. ■Pulmonary disease, associated with looseness of bowels.

153 LYCOPUS VIRGINICUS.

^ Heart, Pulse and Circulation. Constrictive sensation in cardiac region, tenderness : pulse weak and irregular in force.

Acute darting pains in heart, with intermissions of pulse and heartbeat.

Throbbing pain: in cardia; pressure in forehead and eyes.

Sensation of pressing outward in cardiac region.

Oppressed feeling in brain, followed by pain an inch be- low and to outer side of 1. nipple.

Rheumatoid aching in j^riecordial region and at apex, fol- lowed by pains in 1. wrist, inner side of r. calf, and in subclavicular region, and again in 1. wrist and region of apex.

■ Cardiac irritability with depressed force; pulse very fre-

quent, small, compressible, and often irregular and in- termittent; heart's impulse feeble; patient generally nervous, irritable, and his extremities cold; slight hem- orrhages from lungs; cannot go up stairs or v/alk fast without rapid or weak action of heart, or heavy op- pressed action.

■ Cardiac erethism; debility of heart, marked by the influ-

ences of some smouldering inflammation, generally in lungs; heart's action quick ; pulse quick, hard, wir}^ not easily compressible and not generally irregular or in- termittent; local congestion and irritation of lungs; cough; haemoptysis.

■Cardiac irritability, profuse flow of watery, limpid urine.

I I Palpitation in cardiac hypertrophy, with dilatation.

Palpitation and cardiac distress, < morning and evening, and when thinking of it.

1 i Action of heart tumultuous and forcible, could be heard several feet from bed. ^Exophthalmus.

I I It renders beat of heart slower, fuller and more regular.

On lying down,cardiacdepression with dull, heavy beating.

I I Palpitation from nervous irritation, with plethora.

■ Excessive flatulence, which aggravates the palpitations. Labored action of heart ; oppression.

Heartbeats more distinct on r. of sternum.

First sound replaced by a blowing sound of mitral regur- gitation, heard upwards in clavicular region, and par- ticularly between scapulae; second sound pointed, short, sharp.

Heartbeat slow and weak; diminished blood pressure; pulse 48, 58, weak, compressible.

■ Can walk only a few steps without having to stop and

rest, as he gets short of breath; 1. arm, hand, leg and foot oedematous and painful; blowing sound over apex of heart; instead of natural systolic sound, very loud

LYCOPUS VIRGINICUS. 154

sound over base of heart during diastole; pulse quick, weak, frequent, about 90 per minute; feels as though lungs were filled up; panting respiration; urine scanty and high colored; constipation; little appetite, but quite thirsty for cold water; no sexual desire whatever; sleep restless, with frequent starting and jumping; sometimes can lie down, at other times must sit with head high ; tongue flabby, no marked coating; occasionally a sharp shooting pain through from sternum to 1. shoulder blade. ^Heart disease.

iMenses appear within three or four hours of same time every month, with a deep seated pain, with heat in oc- ciput; after a few hours, pain in forehead and temples, faintness and nausea in stomach, sensation of great weakness in lumbar region, general lassitude and de- bility, especially in limbs, followed by torpor and heavi- ness; when nausea set in occipital pain >; aversion to smell of food; protrusion of eyes, wild, strange ex- pression; menses usually appear in morning and flow until noon, then suddenly cease, or they would last from half an hour to six hours, intermitting in this manner for ten or twelve days ; during menses stupid, has lack of expression and a vacuity of ideas ; tympanitis, puff- ing of parts on and around pubis and vulva, dilated condition of vagina and bearing down sensation in rec- tum; on examination vagina very hot, os uteri engorged and swollen; these conditions and puffiness > by local use of ice; constipation, stools every six or seven days, dry and claylike; when eyes seem protruded, heart seemed to act tumultuously and forcibly, and could be heard several feet from bed; at these times puffing of pubis < ; when heart's action was feeble and quiet, with quiet pulse, puffing about genitals > ; at times pulse small and quiet and could scarcely be counted; urine scanty, thick and muddy; oedema of feet; dyspepsia; all, or nearly all, above symptoms > after menses, or at expiration of ten or twelve days. ^Exophthalmus.

I I Aneurism of large vessels near heart.

Pulse: many symptoms increase and decrease, according to weakness or strength of heart's action.

Pulse 80 (while standing), with intermissions, cardiac op- pression. ^^ Neck and Back. Acute pain at seventh cervical vertebra.

Slight rheumatoid pain in 1. suprascapular muscles.

Congestive pain in nape, with severe continuous dorsal and lumbar pain, < lower 1. side.

Rheumatoid pains: scapular muscles, lower dorsal re- gion ; from apex of heart by friction to 1. subscapular region, then to middorsal and later to apex.

155 LYCOPUS VIRGINICUS.

Severe continuous aching in lumbar region.

Sharp pains first in lumbar region, then in 1. leg, extend- ing up thigh, then in r.; feels weak as if overfatigued.

Severe aching down spine, < from friction, passing off after rising, morning.

Flying pains in muscles, with persistent aching in loins and occiput, < on movement. ^^ Upper Limbs. Rheumatoid pains, forearms and wrists, with trembling of hands.

Left leg feels shorter than r. and so sounds when walking.

Lying on r. side: cons.triction of thorax <.

Sitting: giddiness; acute aching in testicle; head high, heart disease.

While standing: pulse 80.

Restless, change of position: in spite of weakness.

Motion: rheumatoid pains <.

Exercise : dyspnoea < ; least, causes palpitation ; aching in loins and occiput <.

Walking: staggering; aching in inguinal canal <; causes shortness of breath, is obliged to stop and rest; sounds as if 1. leg was shorter than r.; unsteady feeling; slight nausea and faintness.

Cannot go up stairs or walk fast: without rapid or weak action of heart. ^^ Nerves. Weak, yet restless change of position.

Restless activity, not withstand nig nausea, giddiness, etc.

Vital depression, hence mental depression, tremulousness.

Faintness: slight nausea, walking in open air; with car- diac depression. ^'' Sleep. Sleep restless, full of troubled dreams.

Wakeful on retiring, though fatigued. ^ Time. Morning : palpitation and cardiac distress < ; menses appear and flow till noon, then suddenly cease; severe aching down spine, > after rising.

1 P.M. : acute aching in testicle.

Towards sunset: erratic rheumatoid pains <.

7 p.m.: constriction in larynx; oppressed, with sighing breathing.

LYCOPUS VIRGINICUS. 156

Evening: increased mental and physical activit}^ ; rheu- matoid pains <; acute pain in testes; cough violent; palpitation and cardiac distress <.

Night: cough violent. ^^ Temperature and Weather. Warmth : direct, does not > muscular rheumatoid pains.

Warm room : > muscular rheumatoid pains.

In bed: muscular rheumatoid pains >.

Open air: faintness and slight nausea.

Change to cold weather: renewed cough.

Cold air: muscular rheumatoid pains <.

Cold winds: renew cough.

Coldest water : alone satisfies thirst.

Ice : local use of, > heat and puffiness of vagina. ^Tever. l Stupid, will not answer questions; is waxy, cold; pulse very low, yet full and large, soft and compressible; hemorrhage from bowels ; tawny, expressionless face ; veins full and face bloated; eyes expressionless and seem to project from sockets; fever not high; chokes and swallows. ^Typhoid malaria. ^^ Attacks, Periodicity. Daily : nine to eleven quarts of urine ; a gallon or more of clear urine.

Every six or seven days : dry, claylike stools.

For ten or twelve days : menses intermit, last from half hour to six hours.

Every month : menses appear within three or four hours of same time. ^ Locality and Direction. Right : tends to stagger to r. ; neuralgic pain in supraorbital region ; toothache in lower molars; pain in temple; rawness at back of palate ; hot aching beneath scapula ; pain inner side of calf; heartbeats more distinct on side of sternum ; pain in leg ; urticaria on leg.

Left: pressure in forehead < ; aching in frontal eminence < ; dull pain in supraorbital region ; neuralgic pain in testicle; pain in molars and temple; tenderness in hypochondrium; dull pain in lumbar region; sharp darting through testicle ; deposit of tuberculous matter in apex of lung ; pain near nipple ; pain in wrist ; arm, hand, leg and foot oedematous and painful ; pain from sternum to shoulder blade ; rheumatoid pains in supra- scapular muscles ; pain < in side of back ; sharp pain in leg; 1. leg feels shorter than r. ; urticaria on forearm.

Right to 1. : rawness of palate ; darting pains in testes.

Left to r. : aching in frontal eminence ; pain in molars.

Pains pass from 1. to r., usually, then they cease or return to left. ^ Sensations. Eyes feel weak as if system was overfatigued ;

157 LYCOPUS VIRGINICUS.

prickings, as if bitten by insects; as if lungs were filling up.

Pain : in forehead and temples ; in epigastric region ; in testicles ; in supraorbital region ; an inch below and to outer side of 1. nipple; in 1. wrist; inner side of r. calf and in subclavicular region.

Severe continuous pain : in dorsal and lumbar region.

Sharp pain : in lumbar region, then in 1. leg, extending up to thigh, then in right.

Acute pain : in testes ; at seventh cervical vertebra.

Subacute pain : across thorax.

Deep seated pain : in occiput.

Acute, darting pains: in heart.

Darting pain : in testicles.

Flying pains: in muscles.

Sharp, shooting pain : through from sternum to 1. shoul- der blade.

Throbbing pain: in cardia.

Neuralgic pain : in r. supraorbital region and 1. testicle.

Severe colic: in abdomen.

Severe aching: down spine.

Acute aching: in testicle.

Rheumatoid aching: in praecordial region and at apex; in 1. suprascapular muscles; lower dorsal region; from apex of heart to 1. subscapular region, then to mid- dorsal; in forearm and wrists; knees, legs, thighs, then to back.

Hot aching: beneath r. scapula.

Aching: in frontal eminences; in r. lower molars, then temples and again molars; in inguinal canal; in loins and occiput.

Dull aching: through sinciput.

Rheumatic pains: around heart.

Circumscribed pain : in stomach.

Dull pain: in 1. supraorbital region; in 1. lumbar region.

Lugging pain: in spleen.

Congestive pain: in nape.

Bearing down : as from hernia ; in rectum.

Burning: in spot in soft palate.

Heat: in vagina; in occiput.

Tenderness: in l.hypochondrium; in bladder; in cardiac region.

Constriction : in larynx ; across lower half of thorax.

Constrictive sensation : in cardiac region.

Compression: in region of stomach.

Pressing outward : in eyes ; in cardiac region.

Pressure : in forehead ; in eyes.

Full, heavy feeling : in eyes.

LYCOPUS VIRGINICUS. 158

Oppressed feeling : in brain.

Distress : in epigastric region.

Trembling feeling : in hands.

Tumultuous action of heart.

Great weakness : in lumbar region.

Lassitude : in limbs.

Rawness : at back of palate.

Flying pains in various parts.

Lowers temperature.

Friction : sends pain from apex of heart to 1. subscapular region ; severe aching down spine < ; does not > muscular rheumatoid pain. ^ Skin. Prickings as if bitten by insects.

Troublesome urticaria, especially on 1. forearm and r. leg, before retiring. ^'^ Stages of Life, Constitution. Woman, set. 33, teacher, nervous temperament, cheerful, sprightly, talkative, in- clined to hysteria, mother afflicted with cardiac trouble ; exophthalmus.

Woman, mother of two children, suffering about a year; diabetes.

Man, set. 43, half breed Indian and Hawaiian, cook on whaling vessel, suffering two or three years ; heart dis- ease. *® Relations. Compare: Cactus, Digit, Hydr. ac.,Iber., Lauroc, Prun. virg., Sanguin., Spigel.

159 LYSSIN.

For historical review, see Bering's Monograph (Jv'orth American Journal of Homoeopathy, 1879).

The first saliva was obtained by Hering in August, 1833 (see North American Journal of Homoeopathy, 1879), and proved by himself in the same year; by Schmid, an AUentown student, in 1835; by Behlert on a number of pro vers, from 1835 to 1838; by Kedman Coxe on himself and family, in 1853; by Knerr, with the 300th and 600th of Jenichen, on a woman bitten by a dog, not rabid in 1869.

Symptoms observed after bites, and those of persons afflicted with rabies, collected from reliable sources, are followed by a dash ( — ).

Clinical reports have as yet been meagre, owing to the comparatively recent publication of the provings.

^ Mind. Loses consciousness for a moment.

Loss of consciousness sometimes at an early stage, but not

more inclined to reflect than talk; not at all lively. Thoughts of something terrible going to happen come into

his mind against his will ; feels impelled to do reckless

things, such as throwing child, which he carries in his

arms, through the window, and the like. Could not get rid of the indescribable tormenting feeling

that something terrible was going to happen to him. Fits of abstraction, takes hold of wrong things, often does

* " We follow the suggestion of Ziemsen, Encyclopedia, vol. 3, p. 472, and sub- stitute Lyssin for Hydrophobinum, as the name hydrophobia, properly speaking, refers to an occasional symptom, and is not a characteristic of the disease of which the classical name is Ai(;qa.^' — C. Hering.

LYSSIN. 160

not know what he wants, says wrong words which have but a remote similarity of sound.

They appreciate the formidable character of the disease and speak frequently with a remarkable quick and sharp articulation of the impending fatal results. —

During the tranquil intervals, responded correctly to questions put to him, recognized those around him, and with a presentiment of impending death, begged them to pray for him and not to leave him alone. —

The majority of patients have no adequate conception of real origin of their malady, and affirm in decided terms that the scar is of no significance whatever and causes them no pain. —

Most commonly the mental faculties are in a superior state of excitement, shown by quick perception, amazing acuteness of understanding and rapidity with which they answer questions. —

Is astonished in his dream at the readiness with which he can express himself in elegant Latin.

It seems to her as if two entirely different trains of thought influenced her at the same time.

A certain confusion, unsteadiness, weakness of mind. —

It is very difficult for him to think, sometimes impossible.

Weary and incapable of mental exertion; school tasks which before had been a pleasure to her, had to be laid aside.

Range of ideas extremely limited, if left to himself is occupied continuously with the same thing, bringing frequently forward samxC ideas within a short space of time and always in same manner.

Dulness and stupidity; at night restlessness.

During convulsions, mental illusions and hallucinations;, in intervals of consciousness mental faculties are re- tained. —

Believe that they are reduced to their present wretched condition by the instrumentality of those about them. —

Imagine that they are being abused, and energetically defend themselves against attacks and insults, which in reality are products of their own fancy. —

Fancies he is being blown at by several persons, some of whom are not present. —

Raved about the dog that had bitten her; imagined it to be near her and fought as if to drive it away. —

Thinks he is a dog or a bird, and runs up and down,,

chirping and twittering, until he falls down fainting. —

They fancy that they see objects, animals and men that

are not present. — Complains bitterly that a fire has been lighted and that

161 LYSSIN.

the stove is smoking, although there is no fire; another

continually directed a window to be closed, which was

not opened. — ■ Strange notions and apprehensions during pregnancy. Slight fits of delirium occur (in advanced state); patients

frequentl}^ forget their friends and relatives ; delirium

attended with constant talking. — Some delirium and illusions ; fancied doctors were two

great authority. — Insane ideas enter his head; for instance, to throw a glass

of water, which he is carrying in his hand, into some

one's face, or to stab his flesh with the knife he is holdings

and abuse those near him. I Inclination to be rude and abusive, to bite and strike..

spring at and to bite any moving object that came within

give me and my young ones something to eat. — After fainting spell he wrote on paper: I am forsaken

by all; even the birds of heaven, they do not look at

me, do not feed me if hungry; I hunger with the young

ones and am thirsty with their she ones; my nest is

made out of dirt, not gotten by my own exertions, but

by driving them out of their nests and sitting there

with the females and the young. — Sang more than usual, but involuntarily; she did not feel

at all happy or cheerful. Goes about house all day singing, moves with greater

VOL. VII. — 11.

LYSSIN. 162

thirst which afflicts them, and by various contrivances endeavor eagerly to drink. —

Had a good cry before going to bed.

Weeps bitterly on account of headache.

Before and after as well as during paroxysms, shrieks or inarticulate sounds expressive of utmost despair. —

During fits, snapping motions with jaws, of an involun- tary and spasmodic character. —

Quiet patients spit into provided vessels, more excited ones discharge saliva upon all sides. —

Biting, snapping, with convulsions. —

Ordered her husband to go away, as she wanted to bite him, and joining act to threat, she bit herself in arm. —

Pieces of carpet put into kennel for dog to lie upon were torn up until they became heaps of loose wool. —

Desperate efforts were made to break chain; dog. —

I Break out of their stables furiously and run or jump over ditches and fences. ^Lyssa of sheep.

He cautioned people around him not to inhale his exhaled air, it was spoiled, stinking like rotten eggs, worse than cholera, and could injure. —

Does not answer questions.

Disinclination to change position of head ; two distinct trains of thought existing at one time in her mind, the idea that she is unable to move her head (when lying down), with the positive conviction that she has only to make up her mind that she will do it to achieve it.

■Not afraid of dogs, but dislikes to see them because their sight renews her fear. ^Lyssophobia.

Cannot bear to hear others sing, or eat apples.

■ Exhilarated, felt as if he had received joyful intelligence. Occasionally exhilarated, then again morose, both feelings

strange to him; feels as if he could do nothing; if he

forces himself he lacks mental power. To such as had continual apprehension respecting their

safety it appeared a shorter time since bite. — Feels as if something disagreeable would happen; when

thinking the matter over, the feeling passes off. He feels as if he had heard unpleasant news, or would

soon hear it ; until 4 p.m. Felt as if she was going to get a fit; at 11 p.m.

■ iLyssophobia; fear of becoming mad.

■ Feels he cannot physically endure his fears much longer.

163 LYSSIN.

and shall be compelled to go into an insane asylum. ^Lyssophobia.

I Mary M., get. 17, had been bitten several years previously by a dog, and reading of several cases of hydrophobia as reported in papers, was found in following condi- tion: crouched in corner of a sofa, dark red bloated face, expression of terror in face, eyes glistening, con- junctiva injected red; was brought into this condition by endeavoring to take a drink of water, and could not hear water mentioned without a shudder of fear, could not swallow, pulse very high, tongue dry and coated red ; Lyssin 2c one dose ; she was better next day, but had several slight attacks afterwards, always induced by run- ning of water, but always yielding to remedy ; has not had an attack in nearly a year.

Felt as if she was going to die; as if she was going to sink away.

She has been unable to sleep a wink for several nights ; is driven from bed by indescribable anxiety; can but sit and walk, or find momentary peace in prayer. —

Anxiety of mind: restlessness, with great prostration; with pain in heart; with headache; fear of being alone.

I A musician received a bite from a small pet dog in calf of 1. leg while walking through a dark entry; the bite was very slight, scarcely wounding skin; the animal was in a healthy condition and remained so ; a pain in bitten place kept returning from time to time inde- pendently of mind dwelling on it, until finally it grew to a burning which extended through entire body, caus- ing an indescribably strange sensation ; in night trem- bling, and a tormenting fear that he would have hydro- phobia; was thirsty and drank water freely; it was two years after the bite when these and the following symp- toms appeared : frequent spitting of saliva all through day, only ceasing awhile after taking strong tea in even- ing; disturbed dreams at night; finally could not par- take of food or drink, and complained of pricking stitches under tongue; mental excitement now as all his life, affects him badly; hot vapor relieved burning pain in bite, and Lyssin 2c (Jenichen) improved all symptoms rapidly; in three weeks he considered him- self cured, and started on a journey.

Indecision even in small matters.

nil humor. ^Headache. ^Diarrhoea.

Fretful, hypochondriac mood in evening.

Feels nervous and irritable.

Very cross, so much so that his children expressed great surprise; he took offence at veriest trifles, scolded his

LYSSIN. 164

wife and children, felt wretched, could not concentrate his attention on anything; sullen, does not wish to see or speak to any one.

After attacks of fury, evinces great regret at his behavior, making earnest apologies, warning those about him not to allow him to bite them. —

Implacable hatred against owners of dog that bit her, with inclination to utter maledictions which, by reason of her careful bringing up and sobriety of her parents, shock her dreadfully. —

Hypersensitiveness of all the senses.

Exalted state of smell, taste and touch, with a feeling of anxiety and a fear of being alone.

Everything affects him more powerfully; also tobacco.

He knew exactly where his nurses, his doctors and ac- quaintances were, if at any distance from him. —

On a watch held to scrobiculum he sees the hour and minute hands. —

He says he can see hands on dial plate of church clock. —

He could hear what was spoken in next room, and count- ing coppers in a room below him. —

He knows every one, and answers questions, also is in mesmeric rapport with his physicians. —

Linen dipped in sugar water, put on pit of stomach, gives a sweet taste in mouth. —

Copper, if in his room, makes him restless and full of pains. —

I Felt same rheumatic pain his brother complained of.. ^Lyssophobia.

Before every spell of somnambulism he crowed like a cock. —

Very uneasy; mental disquietude, with headache.

Driven incessantly about without any definite aim. —

Restlessness, driving him hither and thither, although weak enough to lie down. —

Restlessness and anxiety at prsecordia, frequent change of .posture and sighing. —

■ Restless, constant bleating in a hoarse voice. /?Lyssa

of sheep.

■ Sometimes he could control inclination to stool by a

strong effort of will, but effort caused much nervous irri- tation. ^Chronic camp diarrhoea.

Showing him a bird, he got frightened and thought it was a mouse. —

Was much frightened during attack, and began to pray ; her husband had to sit. up with her and hold her hand;, did not get entirely over attack until 3 a.m.

She feels as after night watching and great anxiety.

Unusually exhausted.

165 LYSSIN.

"While reading and thinking, headache.

Worse while reading or writing; headache; aching in lower jaw.

Severe headache and noseache uj)on going to bed, after writing all her symptoms.

■Attacks of nervous headache become awful and insup- portable if he hears water run out of a hydrant.

Pressing headache, < while reading and thinking.

1 1 When he hears water poured out, or if he hears it run, or if he sees it, he becomes very irritable, nervous ; it causes desire for stool and other ailments.

The mere sight of a drinking vessel containing water is intolerable; they turn away their faces, shriek out loud, beckon anxiously with hands to have the water re- moved, for voice and breath fail. —

iMental emotion always makes him worse.

Mortifying news affects him very much.

A certain w^ildness of humor.

Disposed to get angry; flying into a passion.

Every offence she feels very much.

Excitability prevents sleep.

■ Frequent gaping without being sleepy, most when he has to listen to others.

Thinking of fluids of any kind, even of blood, brings on convulsions. —

The mere idea of drink, fluids, pouring out fluids, may cause a paroxysm. —

Hypersesthesia, rerophobia, current of air, bright light, sight of any shining object, slightest touch, even conver- sation in vicinity of patient, may throw him into a most violent agitation and bring on severe convulsions. —

The mere thought of fluids, of drinking, of swallowing, or offer of anything to drink, is sufficient to bring on con- vulsions; the same effect is produced by other sources of irritation, such as a simple breath of air, the attempt to touch the sick, every hurried approach towards him, the light of shining objects. —

Even the sight of water, or other fluid, or of anything hav- ing the least resemblance to it, such as a looking glass or white substance, whereby an occasion will be given for renewal of idea of their former pain, occasion great- est distress and a return of convulsions. —

Such as were afflicted with grief from any cause were much sooner affected wdth the disease. —

A sudden fright starts convulsions. —

Nose pains from thinking.

Had no symptoms of disease for four months until after receiving very ill usage. —

LYSSIK 166

Dread and fear brought on symptoms. —

Outburst of passion or excesses of any kind hasten the outbreak. —

Any sudden movement near a rabid dog is a stimulus to inflict the fatal bite. ^ Sensorium. l l Peculiar lightness in head ; lightness after nausea.

Singular sensation in vertex, as if he momentarily lost consciousness, but only in that place; or as if a habit- ual feeling had disappeared from there; it is no fulness, no motion, but it causes a vacillating motion of head; in evening.

II Dizziness: as if something was drawing around in a circle, and as if she could not hold her head straight; after lying down, like a shock in upper part of brain ; with inclination to fall to r. when stooping; towards evening in upper part of head, as if she would fall, while walking; frequent and transient; with dim sight while walking and sitting; and nausea; with cramps in ab- domen; temporarily > by return of diarrhoea; < by teaching, spelling, or being obliged to notice letters; after lying down in bed, shock in upper part of brain; dimness of vision on rising from stooping; on rising from a chair, staggers; while sitting; on rising, cannot walk straight.

A slow vacillation or wavering of head, from something being loose in upper part of head.

Surging towards head is felt inwardly, deep in brain.

Dulness: of head; in forehead, more to r. side; in middle of brain,where it surges ; and stupidity at night, with rest- lessness; amounting to pain in occiput.

Sensation as if a small leaden ball was rolling about in brain.

I Rush of blood to head: w^hile lying down; from chest upward, with toothache; during pregnancy; when rising.

Throbbing headache in forehead, vertex and occiput, down to neck.

Burning, surging towards head.

Pain above 1. eye, before going to bed.

167 LYSSIK

organ of firmness; soon after to whole top of head and

to eyes, lasting all day. Dull heavy pain in forehead and sharp pricking in 1.

temple, alternating at times with throbbing and jerking. Pressing in vertex and in forehead, particularly when

stooping or moving head; afternoon. Slight frontal headache in morning on waking, < after

rising. Passes hand across forehead. ■ Maddening outward pressing pain in forehead ; he presses

his head against the wall. Pressing pain in forehead and top of head, returns 4 p.m.,

seventh day, with uneasiness of mind when reading or

thinking. Continual dull pain in forehead, principally on 1. side,

with stupefaction, in afternoon and evening. Throbbing pain in forehead, vertex and occiput, extending

and punching. Boring in r. temple very short, 5 p.m. ; repeats every other

day ; but on fourth day in 1. temple, and in morning

when getting awake. I I Beating, throbbing headache : most severe in r. temple

and above r. eye ; each bone feels shattered and sore ;

from temple to temple.

■LYSSIN. 168

iViolent headache, most in temples and forehead, < dur- ing day and from stooping and stirring about. ^Uterine disease.

Severe pressing pain in 1. side of head, occasionally boring stitches from without in, later pressing extends to 1. side of forehead and 1. orbit ; 10 p.m.

Dull weight, first on 1. side of head, then on vertex.

Pressing weight on r. parietal bone.

Dull pricking pain in 1. side, from head to waist.

Left side of head is now, and has always been, most severely affected.

Headache most severe one and a half inch above 1. ear, in evening.

Piercing pain in r. side of head, with sensation of stiffness, or as if part would become insensible.

Woke in morning with a burning, aching headache in 1. side of head and down neck.

In vertex: dulness and tensive sensation; stupefied feel- ing ; vertiginous shocks ; a peculiar sensation ; pressing weight ; pressing stinging, r. side ; pressing shooting ; pressing beating; pressing heaviness, r. side ; strange pulsation ; burning surging ; throbbing.

Pressure in upper part of head and forehead : < stooping or moving head ; at 4 p.m., while reading and reflecting, with mental restlessness,

I I Frequent pressure on vertex, as if a cast, which fitted top of head, was pressing it down.

Severe headache, extending from behind forehead to organ of firmness, soon after spreading over vertex and to eyes, at 2 p.m., lasting all day- Pressing from forehead to vertex and jaws.

Pain on top of head and in teeth running into each other.

Painful pressure, most on upper part of head, < when moving head; later also in forehead, with considerable heat and prostration.

In occiput: painful dulness; pressure in 1. side; tearing and stinging as if in bones, < after rising; aching; burning; pain in 1. side, < during wet weather; dread- ful pains running up neck and down spine, < when lying down.

Sharp pain across eyebrows and up nose, while walking out doors; exceedingly fatigued and weary after a short walk.

Intolerable headache extending to ends of nose and into teeth ; some pressure on head, and for a moment a feel- ing as of an invisible hammer striking upon back of head (relieved by Tabac).

Frequent attacks of headache, in which head, nose and teeth appeared to be soldered together.

169 LYSSIN.

Feeling of tension in head; much pressing pain in head. Head feels as if it would split with severe pressure on vertex.

I Pain as if head would burst. ^Pregnancy.

At 3 P.M. : headache very severe; dull heavy pain in head. ■Afternoon, pain in head; sick headache.

I I Headaches from bite of dogs, rabid or not.

In rare cases serous effusion in opaque subarachnoid tissue and lateral ventricle, and also increased adherence of membranes of brain to convolutions. —

All morning severe headache which makes him impatient.

I At noon slight headache, lasting all day.

Dull heavy pain in afternoon in head.

Painful rush of blood to head after moving, turning around, or stooping.

Unbearable headache for three days makes her snappish, harsh and irritable; trifles annoy her; lower jaw feels stiff and aching, hands numb.

Crying bitterly during headache.

A peculiar sensation in head all day, as if something drew the head towards shoulders.

Headache with nausea and sore pain in heart, in after- noon; > in cold air.

Pain from mouth up through head and down back of neck.

I I Burning aching from 1. side of occiput down neck.

• Violent headache and backache.

Painful pressure on top on moving head, with fever and prostration.

Horrible headache, accompanied by general weariness.

Headache in bones of skull.

On top of head, pressing heaviness, same in r. parietal bone.

Tearing and stinging in occiput, as if in bones, < after rising.

Right side of head feels stiff, as if it would become numb.

Numbness of 1. side of head.

Very annoying headache, more outside, near vertex, > by gentle scratching, or by rubbing, but it must be done by hands of others, thus by a kind of mesmerizing.

A darting from within outward to scalp, on r. side of ver- tex, followed by itching.

Itching in locality of acquisitiveness.

Small pustule, painful when touched, on 1. frontal emi- nence, later same on richt.

LYSSIN. 170

Hair which is usually dry has become very oily.

Scalp feels contracted and pinched. ^ Sight and Eyes. Sensitive to light.

Left eye exceedingly sensitive to light and water.

iSight of water; agitation; renews idea of pain; causes convulsions (pregnancy).

Sparks before eyes.

Something moves to and fro before eyes while sewing, but always a little farther off the point at which she is looking.

False vision, dulness of sight, together with dilatation of pupils, sometimes actual blindness.

Great weakness in eyes, without pain.

■ Since five years could not read longer than a few minutes at a time, when she would see letters double and would read something else than the right words ; had tried all sorts of spectacles without benefit, was often ashamed because she could not sign her name properly.

On looking up eyes are very weak.

Dimness of vision : with vertigo ; dizziness when walking and sitting.

Vision much impaired or absent ; lasts twelve hours.

Vanishing of sight.

I Could not see or hear. ^Lyssa.

Drawing, beating pain over r. eye, extending into eyes.

Aching over eyes, as if in bone, < r. side and stooping.

Pain over r. eye, pressing inward.

Pressing sensation in upper part of r. orbit.

Drawing, beating pain over eyes and into balls.

Throbbing over r. eye.

At 9 P.M.: severe shooting pains in head, over eyes and in temples ; also very violent aching pain isiside of and all over chest.

Pain over 1. eye previous to retiring.

Sharp pain across eyebrows, afterwards burning in e^^ds.

Pain in small spot over r. eyebrow, < writing.

Soreness in eyes and above them, pain in forehead.

Pressing sensation in orbits.

Headache extends into r. eye.

At 9 P.M. felt a curious stinging pain in 1. eye, extending to forehead, over r. eye, painful.

Eyes feel very bad, severe pain in them and in all his joints.

Eyes ached intensely; feeling of soreness.

Burning of eyeballs.

Eye draws heat from nape of neck.

Itching heat in eyes.

If mental anxiety is great, pupils are in some cases dilated, while face and conjunctivae are injected.

During period of tranquillity, in last stage, pupils are con- tracted or of unequal size, eye fixed, strabismus. —

171 LYSSIN.

Pupils were a little dilated and eye had a somewhat wild

dilated pupils, upper lid drawn up, and diminished

■ Great inflammation in an eye from which gushes foamy

pus ; pustules around eye ; in morning lid puffed up like an eggshell, small pustules on one finger. ^Dog- bite.

Eyelids fly open involuntarily.

Pressure in 1. side, shooting to eyes in evening.

Burning in lids.

Eyelids feel paralyzed on awaking in morning, and ap- pear to be more firmly closed, as if glued together.

I I Swelling of eyelids after bite of dogs. ^In sheep.

■Extreme ulceration of eye, lids closed and puffed up by pus. ^In sheep. ^ Hearing and Ears. Conversation in vicinity of patient may throw him into a most violent agitation. —

Ringing of church bells makes him anxious, and causes a sharp salty taste, with stitches in heart. —

Water poured into a basin, with splashing noise, caused paroxysm to be reproduced, with convulsion and agita- tion. —

Sudden noise causes involuntary startings.

■ ■Hearing water poured out in next room makes him

very irritable and nervous.

On crossing ferry, soon after eating, noise which water made caused unspeakable torture in her back. —

Convulsions excited by barking of dog, from great sensi- bility ; any other sudden noise, shutting a door or a blast of wind, produce the same. —

■ During his attacks of chronic headache, which come

after mental emotion or excessive mental exertion and last a day or two, he cannot bear to hear running water; if hydrant is allowed to run in an adjoining room, or even if water is poured into a basin, his headache in- creases to an insupportable degree.

LYSSIN. 172

I After the pain following an evacuation had lessened, and he was sitting at open window, the large street waterplug was opened to cleanse the streets, and as soon as he noticed water running down gutter in front of his house, he was seized with violent pains and had to go at once to the watercloset. ^Dysentery.

I If during night, or in morning before rising, he heard pouring out of water in next room, he was immediately obliged to rise and have an evacuation. ^Chronic camp diarrhoea.

■ Hearing water poured out brought on convulsions. ^Pregnancy.

Sensation as if blood rushed to r. ear, then a pressure as from a dull knife, interiorly and superiorly.

Sound as of rushing water in 1. ear. —

Buzzing in r. ear.

Hears various noises in night.

Temporary stoppage of r. ear ; about two hours afterward while thinking upon it, ear commenced aching; pain extends into teeth and through head.

Tearing pain from lower jaw into ear.

Rending pain in r. ear.

Shooting and stitches in r. ear, from without in.

In morning, pressing in forehead and drowsiness, with stitches passing inward in both ears.

Stinging pressure behind ears; afternoon.

Rush of blood to r. ear; after it a pressure like from a dull point.

Pressive burning in r. external ear.

Burning and heat in ear.

Earache extends into teeth.

Tearing pain a few inches from r. ear.

Pressing from nape of neck into ear.

Above 1. ear, headache most severe.

Pressing burning in r. concha, in evening.

The ears feel stiff.

Ear tickles, after rubbing pain.

During three days her sense of smell, which is always ex- tremely acute, became painfully s§, particularly in reference to unpleasant effluvia; action of nostrils ex- tremely painful.

The greatest sensibility to smell of tobacco ; tastes snuff while box is one foot distant.

Frequent bleeding from nose; repeatedly some clotted blood in nose.

173 LYSSIN.

Tickling in nasal cavity causes sneezing.

Itching in nose all day.

Repeated sneezing, which stops on being interrupted.

Frequent sneezing, mostly early in morning or late in evening, as if a coryza would begin; also when looking at something bright, and from every little dust.

Fluid discharge from nose.

Coryza, with tickling in roof of mouth and in front of nose (relieved by Phosphor).

Thick green mucus runs out of nose (horse).

Pain in nose.

Sensation of stiffness in nose, in r. side of neck, and prin- cipally in jaws.

Nose feels bruised.

Nose, r. neck and side feel very stiff, more about jaws.

Nose extremely sensitive to touch.

Headache extends into nose.

Nose itches all day. ^ Upper Face. Jawbones feel quite sore.

Both jaws feel stiff; tingling in cheek bones.

Gnawing and crawling sensation in r. zygoma.

Transitory drawing in 1. side of face, from cheek bone toward nose, as if in muscles, in evening.

Tearing in r. upper jaw extending into ear, same in temple.

Shooting pains in upper jaw and violent headache.

Darting pains in r. side of face.

Burning neuralgic pain down 1. side of face.

A sensation moves about in r. side of face and goes across forehead.

Slight twitchings in face and hands.

Quivering in face.

Facial muscles become variously contorted, countenance changes its aspect frequently.

Spasmodic affections take place in muscles of face, occasion- ing violent contortions and most horrid assemblage of features; in muscles moving lower jaw, inducing invol- untary gnashing and a grinding of teeth, which some have construed into a desire of biting; during convul- sive attack expression of face indicates great anxiety and alarm. —

Disturbed look with dyspnoea. —

Expression of face quite variable ; reddening countenance often exhibits reflections of utmost mental and physical misery, of most horrible agony. —

Face flushed ; complained of his head, said they were run- ning needles into his brain. —

Heat in r. side of face and r. ear, followed by headache in vertex and forehead ; as soon as headache gets >, heat

LYSSIN. 174

returns; heat comes from within, and spreads from back of neck to ear and into eye and face, accompanied by constant pain in nape of neck, which increases after heat and headache disappear.

A feeling of heat and soreness in middle of 1. cheek.

Heat in face, with soreness of 1. cheek, from thinking.

Heat in r. side of face, and particularly in eye, where it causes a tickling ; returns after drinking coffee.

Face sweat: with sensation of heat; with flushes.

In morning (6 a.m.), tickling in 1. cheek.

Heat and redness of face.

First heat in r. side of face and in ear, then a quiet aching in front of upper part of head ; this headache lessens, the heat increases.

Heat in face in morning, with redness; at times very deep.

Complexion pallid and cyanotic, and expression stupid.

Flushes and headache alternately.

Pale face with squeamishness and nausea.

Face pale and yellowish, almost brownish.

■ Appearance peculiar; skin sallow, pale or anaemic; bloated all over, but no "pitting." ^Chronic camp diarrhoea.

Sensation as if she had been bitten in 1. side of face near mouth.

Tickling on 1. cheek, at 6 a.m.

The scratches on cheek became red, thirty- three days after bite, and on following day looked quite fresh, as if they had been made only a few hours before, but were a little darker in color than newly made abrasions. —

Pimple on eminence of forehead, painful to touch ; later one on right.

On 1. cheek near nose, towards eye, a pain, < when touched ; a pimple with soreness around.

Painless hard nodules on cheek, where a pimple seemed to have appeared ; on ninth day a little scurf on it and redness ; if picked or pricked, a very disagreeable kind of pain, but not violent, is felt in cheek even a distance from nodule, and here and there deep in upper part of jaw ; gets bluish red and soft ; discharges, after the scurf is scratched off, lymph and blood.

Slow maturing bluish pimples on face.

I Pain in 1. cheek near nose, from fifth to seventh day; followed by a hard, painless swelling of size of a pea, turned redder on thirtieth day, and became covered with a small scab ; on thirty-second day it grew soft and turned bluish red, particularly around edges ; on puncturing, a disagreeable yet not severe pain at some distance from swelling and more inside of cheek ; a

175 LYSSIN.

small quantity of blood and matter was discharged ; on fortieth day the place ceased to discharge and healed. ^ Lower Face. The jawbones feel sore ; aching in lower jaw.

Violent jerking pains in lower jaw.

Tearing in r, lower and upper jaw up into ear.

When reading or writing, felt a pain in lower jaw ; the longer she reads the < it got.

I I Masseter muscles not affected by spasms.

During phrensical fits, snapping motions are made with jaw of an involuntary or spasmodic character, bearing some resemblance to motions of biting. —

Attempted to bite her fingers before death. —

Biting snapping with convulsions. —

Jaws feel stiff; crawling in zygomatic arch.

Lower jaw stiff and painful ; with inclination to yawn ; with headache ; imagines he cannot open mouth.

Jaws feel sore and stiff; a great disposition to press hand against lower jaw.

Sensation as if she would have mumps.

A chilling, biting, burning sensation on inner side of r. ' upper lip, as if a corroding acid had touched spot ; sen- sation passes up and back, in a lesser degree, to r. nasal cavity, where it produces tickling and sneezing; sub- sequently increase of saliva ; after several hours.

Lips cracked on inside of middle line.

Spasms with froth before mouth. —

It seldom happens that froth is observed around outside of mouth. — ^^ Teeth and Gums, i Grinding of teeth.

Painful sensation of coldness shoots into teeth, it passes from lower posterior part upward and into jaw.

Teeth hurt more on r. side, it is a kind of aching dulness.

Sensation in r. lower jaw, in bone as it were, it shoots into root of a decayed tooth.

Shooting pain in r. eye tooth, preceded by burning, passing down oesophagus.

Frequent shooting pain in teeth; all the teeth ache.

Aching in carious root of a molar.

■ Toothache and other complaints during pregnancy, with

internal ebullition of blood from chest to head ; head

below in bone of lower maxilla and passes upwards. Neuralgic pain in gums, principally in front. —

■ Aching in swollen gums on r. side. Drawing in gums, most in front.

LYSSIN. 176

to lack salt. Speech is labored, short and pathetic. — 1 I Difficult, incorrect speech. ^Stricture of throat. • Impediment in his speech, would begin a sentence with

difficulty after several fruitless attempts; some palatal

vowels he could not pronounce, others but incorrectly.

■ Pricking sensation under tongue. ^Lyssophobia. Ranula returns periodically, with dryness of mouth, <

■ Constant sensation of intense dryness of mouth and

■ Tough, short frothy phlegm in mouth (horse). Frothed at mouth, attempted to spit out with much diffi- culty (before death).

Saliva more viscid, constant spitting, feeling of general

malaise. Saliva runs together in mouth, without occasion; flows

back and is swallowed. Saliva in back part of mouth like after sugar, or when

Saliva more plentiful, but thin and of yellow color.

177 LYSSIN.

Secretion of a thick and frothy saliva, but without any- morbid repulsion towards drinks.

Ejected saliva is frothy, slimy and ropy.

Much tenacious saliva, with sore throat.

I Large quantities of tough saliva in mouth, with constant spitting. ^Diarrhoea.

Saliva is not ejected, but runs from open mouth. —

Quantities of saliva are collected in and about mouth ; presents a frothy appearance; patient is constantly en- deavoring to get rid of it by wiping it with a hand- kerchief, or spitting it out with great force. —

I Spits all the time small quantities of a frothy saliva ;

with pain in limbs.

I I Frequent spitting. ^Lyssophobia.

I At 10 A.M. began to spit a great deal, continuing all day

nares. Scraping sensation on palate where cool sensation had.

been, slight coughing does not reach spot, hemming-

and hawking does occasionally. Fauces and pharynx pervaded by an equally diffused

purplish scarlet blush, no pain in throat, except when

patient attempts to swallow. — Follicular enlargement is common, involves also pharyn- geal follicles and lymphatic glands in neighborhood of

jaw; similar swelling upon inner side of epiglottis,

pretty firm and characterized by abundance of lymph

corpuscles found in gland substance. — Hyperplasia and recent swelling of tonsils and follicular

glands of tongue; flat, roundish swellings at root of

tongue, in middle of each one of which was seen dilated

opening of a follicle. — Sensation as if uvula was too long; it is slightly inflamed

but not elongated. Mucous membrane of pharynx and epiglottis of a deep

red color and injected; soft palate frequently reddened

and swollen. Entire mucous membrance of mouth and pharynx was of

an equally distributed pink without any swelling. '^ Throat. I Slight redness of palate and throat, with spasm

attempting to swallow liquids, which he could not do

without pain ; solids not painful. At 11 A.M. : soreness in throat till noon.

VOL. VII. — 12.