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Bellis Perennis

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General EN

{English Daisy.) Description The only Bellia (Daisy) iDdigenous to tlirs couiifry — B Integrifolia ; grows proflisely all over tho United States; has probably Uie same properties. Tlie B. perenitis is a native of England. Officinal PitffiPAKATiOBS

Tincture of the plant; infosion. Analogues.— .ilmiVo, ffamamelia, (f) Mhua. (?) Leueanthem.wm. A large boil on the back of my neck, (for the first time in my life,) right side, commencing with a dull aching pain; some difficulty and bruised pain in keeping the head erect; slight nausea, want of appetite, and a little giddi- ness in the head.

Pain in the little finger of the left hand, as of a gathering; at the same time pain in inner side of left forearm, as of a boil developing; afterwards similar pain in right arm. A boil beginning as a slight pimple, with burning pain in skin, increasing until in six days' time it was very large, of a fiery purple color, and very sore ; burning and aching pain in it, accompanied with headache, extending from

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BEHZOATE OF AMMONIA. 97

occiput to siiicipnt; of a cold, adiing character. The brain felt as if contracted, with vertigo. This was fol- lowed by other boils. {From proviiigs hy Dr. Thomas, m '^Additions to Mat. Med." Zondon, 1868.) ' Eoils, all over the bodj. {Dr. Thomas.) (, with extra^asated blood. {lb.) s of ankle aud wrist. {H-) " Whitlows. {lb.) (Dr. Thomas used it in. the same manner as Arnica.)

EENZOATB OF AMMONIA.

(AmnKmia Bensoat.) Phakmacoloqy.- — This salt may be matle as follows: Take of solution of ammoaia three fluid ooucea (imperial measure), beaxoic iicid two utmcefi (sToirdupois), distilled water four ounces; mix the solutioc of amnionia' and the wsfer, and dissolve In them the benzoic acid ; evaporate at a geniio beat, keeping Mmmonia in a sliglit excess, and set aside that crystals may

It is in minute, wliite, glistening, extremely thin, four-aided laminre,, having a slight odor of officinal benzoic acid, and a bitter, saline, some- what balsamic taste, leaving a slight but persistent sense of acrimony on' the tongue.

Soluble in water and alcohol, when heated sublimes wiUioot residne; but is probably changed into acid benzoate.

Officinal pRBPARATiONe. — Triturations; tinctures in dtstilled water; dilutions to tlie 8<1 x with water.

Tlie Benzoate of Potassa is now used more extensively, and may be the best preparation. AWALOeUES. — Benzie acid, Colchieam, Ferr. inur. I/ycopoeliwm. ( t)

Head EN

Bheumatic pains about the head aud neck. " Heaviness and stupidity of the head, (in dropsy.)

Pace. Bloated face, with swollen eyelids.

Upmary Organs. * Very scanty, dark-red, bloody -looking urine, with strong'

aminoniaeal odor, and red, thick sediment.

Scanty, dark and smoky-looking urine.

Frequent desire to urinate, with scanty discharge.

Tlie urine is acrid and irritating, (primary effect.)

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OS BERBEBIKA,

Profuse and frequent tirination.

Clear, limpid, and abundant urine.

The sediment disappears from the urine, (secondary.)

" Nocturnal incontinence of urine.

* Scanty, blood-red urine in rheumatic affections.

° Urinary troubles of infants.

° Dropsy after sca/rld fever, or Bright's diseases.

Extremitiea- " Rheumatic affections of the arms and legs and small joints, " Dropsical swelling of the legs. ° Jaundice, from suppression of the biliary secretion (not

trom obstruction of the ducts). {Harley.') 0(nit^ when the small joints are red and swollen, or when fluid

is deposited in the joint of the great toe; and also in

cases when the lithate of soda existed in the joints of the

fingers. (^Seymour.) " Albuminuria/ the albumen in real dropsy diminished under

its use. {lb.)

BERBEEINA.

Peakmacology

Berberina is obtained from many plants, notably from Hydrastis, Coptia Columbo, as well ns IVom the Berberis vulgaria, from ■which plant it takes its name.

It is the yellow principle of tUe roots of all these plants.

The Hydrastia sold as the active principle of golden.seal is principally Berberina.

The true Hydrastia is composed of colorless crystals.

The salts of Berberina, as well as the alkaloid itself, is very sparingly solnble in cold water or alcohol.

The Muriate of Berberina is generally used, although many physicians prefer the Sulphate.

A phos- phate is now extensivelyused, under the name of Pliosphate of Hydrastia.

I think the Hypophosphite will be found superior to all others of its salts.

Tlie wrongly-named Muriate of HydtasHita, as well as oilier salts of Hydrasfjiw, are all salts of Berberina.

Ofpicthal PaEPARATiONB

Triturations of the alkaloid or its salts.

ANAL0OUE8

Aktrig, Ohina, (Quinia,) CoptU., Ool-ambo, Berberis, Bydra«- tia, Beloniaa, JVux vom., Pte'ea, Ferrum, Qentiana.

(See Therapeutics of Byda-iutu, and compare Pathogenesis of Berberis,)

^ Muscular debility, atony and wasting.

"^ Myalgia, and all the pains iiicident thereto.

" Enlargement, of the liver, (and spleen?)

' Intermittent fevers; remittent fevers.

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M-SULPHIDE OF CAKBON.

° Loss of appetite, with slow and imperfect digestion.

[Useful in all esses ivliere Hydrastis is recommended eccg»{ in diseatet of mueoua membranePi

BI-SULPHIDE OF CARBON.

(_04Wbwretv,m Sulphwrii.) Officihai.

Prbtarations

Tincture and dilutions.

Mental Sphere.

Loss of memory, and merita,! alienation.

Great absence of mind, with difficult comprehension of what

is read. They forgot what they had to do; sought for things which

were lying before them; coiild not find the right words

when speaking.

Cheerfulness, with inclination to sing.

Exhilaration bordering on intoxication.

Vehement and irascible.

Dejection of spirits.

Head EN

Ifrequent attack^ of vertigo when sitting. Dullness and vertigo in the forehead. ° Intoxication, to entire loss of consciousness, from drinking

whisky.

" Asphyxia, from alcohol and from coal gas.

Great dullness of the head.

Pressing headache in the forehead, aggravated by reading and

stooping. Pressing frontal headache, with occasional flying, tearing pains

in the temples. Drawing, tearing pain from the forehead toward the temples;

better in the open air than in the room, wiien at rest. Frontal headache, more of a tearing nature, which goes toward

the temporal bones. Frequent, transitory, jerking stitches in tke forehead ; heat in

the head and face. Violent, pulsating pains in the temples (megrim), on awaken-

ing in the morning. Head very painful when brushing the hair, particularly on the

verteL.

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100 Bl-SULFHIDE {

" Violent pain in the Lead; headache increasing tinti] it causes

confusion. is^ mind; feverish attacks; cold extremities, aJid

spasmodie pulse. Pain in the head is ecHinected with the discharge of blood with

the stool.

Eyes, Weakness of tlie sight; objects seem as if fading away, on

acconnt of a mistiness, which spreads out before them. Pupils enlarged.

Sensation of pressure in the sockets of the eyes. Jerking stitches in the muscles of the right eye; intermitting

and alternating.

Burning in the eyes, with pain in the forehead.

Heaviness of tlie eyelids, and dimness of the eyes.

A small pustule on the apper eyelid, with itching- burning.

Eye sunken, with strongly marked gray rings.

Quivering of the eyelids.

Ears,- Viohnt stitcTtes and emitraetive ■pam in the jeft ewr, at night.

Pressing, boring pains in the right ear.

Kinging in the ears, I'asting^ several days.

Everything smells like tiie drug.

Frequent sneezing.

End of the nose barns^ an<I is quite red ; eruption on the nose.

Pace. Face bloated np and red; convulsive jerking of the corners

of the mouth. In the -momings, after shavmg, a red empiion on the cheeks

and nose similar to the eruptions on the noses of hard

drinkera, looking like tetter, and lasting till night. Eruption makes its appearance after drinking a glass of beer.

Mouth EN

Saltish taste of the phlegm' haiwked' np from the fauces.

Constant accumulation of sweetish tasting water in the mouth.

Increased flow of saliva, with increased appetite.

Toothache, with a gradually formed swelling, around the pain

ful tooth.

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BI-StTLrHIDE OF CAHBON. 101

Drawing, tearing toothache, fyom evening uotil miduiglit,

more endurable in the greatest col(J.

Toothache in the molars of lower jaw, right side.

" Toothache brought on by warm food. ° Neuralgic odontalgia.

Sensation of coldness, first on the tongue, then in the month,

which quickly rises to a stitching burning. Burning, pungent pain on the tongue, ae from peppermint,

with peculiar onion or garlic taste. Tkroat Immediately after lying down, tickling in the posterior portion

of the palate, causing a violent dry cough. " Rough, scraping pain in the left side of the throat when

swallowing. " Burning and scraping in the whole of the (esophagus, with

difficult swallowing. Severe stitching, contracting pain in the upper part of the

tesophagus, as if a piece of bone had lodged there. ° Chronic pharyngitis. Scraping, scratching feeling, with fine stitches in the throat.

Appetite—Thirst. Increased appetite, with a pleasant warmth spreading through

the stomach. Groat thirst; beer relished unusually.

After breakfast, headache, pressure in the stomach, diarrhcea. After dinner, diarrhcea; tickling in urethra; pain in thigh;

pain in feet, ifter eating, and in the cold, all the symptoms disappear, or

ai-e ameliorated. Aggravation of tlie symptoms from wine.

Stomach EN

Rising of flatulence, tasting and smelling of the medicine;

also disagreeable, putrid -tasting, nauseous fluid.

Acrid, burning eructations.

Heartburn so severe that it causes cough.

Extraordinary amount of loud eructations, and very stinking

flatus in the evening; better from helchingj inclination

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102 BI-8CLPH1DE OF CAKBON.

to vomit; pain in scrobieiiluni; pressure of stomac-lk; impeded respiration.

Vomiting of greenish, bilious masses, accompanied witli nausea, cold sweat, and dejection of spirits.

Increased aiuouat of saliva in the mouth and stomach, pro- ducing nausea; aecnmulation of water in the mouth; eructations; fnllness in the stomach and abdomen; rum- bling and cutting in the abdomen, from wind; also cntting, tearing belly-ache; a bubbling in bowels, relieved by copious diarrhteic stools; also producing dullness of the head; attacts of vertigo; pressing frontal headache; surly mood; sleepinees during the day, and sleeplessness at night; confused dreams.

Inclination to vomit on entering a room, or when going out from the room to the open air.

" A single attack; vomiting a small quantity of bitter water.

~ "' s of the stomach, with belching, yawning, and inclina- tion to vomit.

;. tearing pain in the chest, stomach and abdomen.

"Pressure in the region of tlie stomach, and under tlie ster nnm, with hepatic depression.

Pressing, stitching pains, of short dnration, in the pit of the stomach, beginning at one point and radiating to the cardiac region, like neuralgic colic, followed by loud belching, which gives relief.

Very severe stabbing pains in the stomach.

Burning in the stomach and region of the liver, aggravated by pressure.

Pressure on stomach and abdomen increases nausea. Hypoehondrium.

Diseased condition of the liver, with swelling of the feet.

Unpleasant, undefined, painful feeling in the region of the left lobe of the liver, coming on in attacks; this pain changes to a pressing (distending), stitching feeling.

Under short ribs, stitches.

Abdomen EN

Pressing, cram py pain in the abdomen; passing much flatus, both up and down.

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BI-BDLPHIDE OF CAKBON. lOS

Pains in the bowels, with twisting, rolling, and rumbling, &a if diarrhtea would set iu.

"" Coliciky pains, cutting, with diarrhoea.

Griping pains in the bowels, followed by stool; after the stool the pains cease.

On awaiting at 4 a. m., cutting in the abdomen, with a moving swelling as if from flatus or incarcerated wind; on taking a deep inspiration, and from pressure, this pain changed into a stitch pain, and settled in the region of the cceeum for about one honr; small passages of wind has no intlu- ence on this condition; turning in bed or bending in- creased tlie pain or brought it on anew after it had nearly passed off.

°Puffiness of the abdomen, with bruised, sore feeling of tlie abdominal walls,

" Fullness and distension of tlie abdomen.

''Flatulent complaints; sour smelling flatns.

Single, fine, jerking stitches, extending from the right side of the umbilical region toward the bladder.

In ocecal region, on taking a deep inspiration or from pressure, a cutting in abdomen changed into a stitching pain, set- tling in cceeum, often repeating.

° Strangulated hernia.

Stool EN

Papescent stool, with urging; during the passage, and par- ticularly afterwards, a feeling of weakness and trembling.

Stool always papescent and small; papescent stool with dis- charge of blood.

Papescent stools, preceded by the peculiar stitching, distending pains in the abdomen, and followed by griping;, stitching pains in the cceeum.

During rumbling in the bowels, violent diarrhtea of sonr- amelling stools, with tenesmus.

I at 5^ A. M., with urging to stool; profuse, thin, yel- lowish evacuations, followed by burning at the anus, as from an acid. . chronic diarrhcea, which set in every four or six weeks, and lasted for one or two days; yellowish, frothy, sonr-

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104 BI-6ULPHIDE OF CARBON.

SDielling fluid evacuations, witli tencemus and ■colicky

belly-ache, particularly in the umbilical region, in the

night. DifBcult, small stools, even when the passage is snaall and soft,

as if from want of power in the rectum, " Constipation, with belching after eating, with herpes. No desire for stool for three days, when he had a soft passage,

with discharge of bright i-ed blood. ° Griping; urging before; pains before; tenesmus with the

stool; with diarrhcea. Anus and rectum, stitch-like, cramping pain; likewise in the

bladder and uretlira. Burning and itching at the anus, with flying stitches in the

Urinary Organs EN

After drinking a glass of wine, on urinating at midnight,

violent, stitch-like, cramping pain in the bladder and neck

of bladder, extending throngh the urethra; at the same

time a similar pain in the anus and rectum. Burning in the urethra when urinating; slight irritability of

the mncous lining of the urethra; urine smells like suU

phur; increase of sulphates and carbonates i/n the urine.. Strong urging to urinate.

Sexual Organs EN

Entire want of sexual desire, and of erections; inability to

have sexual intercourse (constant); increased eexnal desire

was observed in only one case.

Complete impotence, with atrophied testicles.

Erection at night, with emission of semen.

Stitching, burning pains in the left .seminal cord, up to the

abdominal ring. Jerking, stitching pains in the left testicle and left seminal

cord.

Left testicle and epididymis swollen and indurated.

Scrotum and penis shriveled and drawn up during the entire

proving. The previously regular menses appeared three days too soon. ' I^bor-pains too weak.

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BI-BCLPIIIDR OF CAKBON. 105

Larynx EN

Sensation of contraction of the larynx upon swallowing the

drug, producing great irritation to cough, even to stran-

gnlation, and expectoration of mucne. Scratching and scraping leeling in the throat; irritation to

Cough EN

Violent dry cough, from tickling in palate after lying down. Immediately after lying down, violent, asthmatic, dry cough,

hronght on by a continued and irritating tickling in the

upper part of the pharynx, causing mjicli straining of the

chest, and producing pain. Cough from irritation in larynx, even to strangulation, and

expectoration of mucus. Anxious breathing, with pressure on the sternum; aggravated

by the close air of the room and from going up stairs. Expiration hot; breathing difficult; flying stitches and burn- ing in the chest, quickly passing over, but frequently

repeated. Difficult breathing, with nausea.

Chest EN

Throughout the whole chest, agreeable warmth, ascending

from the pit of the stomach. Congestion of the lungs, which appears to aifect the upper

lobes most. Deposit of tubercles in the lungs, some ecchymosis and some

infiltration. (Eabbits.) Hepatisation of the lower or posterior lower surface of the

Lungs EN

(Rabbits.) ° In the first stage of tuburculosis of the lungs, before any, or

yet only slight, fever has set in, flying, burning and

stitches in the chest; quickly passing heat of the feee;

dry cough; diflieult breathing when moving.

" GoTisPrictive, stitching, pressing jxiins in the chest.

Jerking, stitching pain, first in the region of the right, and

then of the left, lower ribs, quickly coining and going.

Periodical stitches in the left half of the chest, without cough.

Several violent stitches under the centre of the stemora,

shooting upwards like a flash of lightning.

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106 BI-SULPniDE OF CAKBON.

Heart EN

"Palpitation of the heart, with antemic patients in an advanced

stage of the disease; nun's murmur in the vessels of the

neck; fever symptoms not frequent, and mostly at night.

In one case, diminution of the pulse to fifty-two beats in

a minute.

14'eck and Back.

Painful stiffness in tlje neck and throat; rheumatie-like pains.

" Goitre.

Feeling as if a heavy load was hanging on the back (from one

scapula to the, other), weighing him down so that the

head sank tbrward.

Continual backache and pain in the loins.

Violent pains in the back and loins, in the morning when

awakening.

Upper Extremities. Stitches from the shoulder joint to the elhow, or even to the

wrist, especially violent after midnight, and during damp

or cold weather. "Crackling in the right shoulder joint from strong motions

of the arms, either forward, backward, or upward. " Crackling in the right shoulder joint from every motion,

connected with more or less severe stitches from the

shoolder joint to the elbow, on every change of the

weather.

Violent rheumatic pain in the right arm, shoulder and neck. ° Pimples on the right forearm and hands.

Jerking pains in the joints of the hand, coming and going.

" Gout of the hand.

Itching and smarting of the hands, particularly between the

lingers, where he discovered small vesicles. ° Vesicular, scurfy herpes on the dorsum of the hand. Pricking, stitching sensation in the lingers, more or less

through tlie whole day.

Lower Extremities. Jerking, stiteliing pains at different places, particularly on tlie

tnbei- ischii, and at the insertions of the gracilis and sar-

torious muscles at the knee.

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BI-8ULFHIDE OF OAEBON. 107

" EJienmatism of the lower extremities; the slightest motion brings on violent pains, partieiilarlj in the hips and knees, with redness and swelling of the feet from a severe cold.

" Dropsical swelling of the feet, arising from diseased condi- tion of the liver.

"Inflammatory sciatica in left tliigh, brought on by taking cold, with entire inability to walk,

" Chronic sciatica in right thigh, movements of the iimbs impeded.

Tearing pains in the right knee and ankle joint.

" Jerking, flying, stitching pains in the legs.

Violent pains in the ankle joints, as if broken, in the morning in bed; after getting up, the walking, at flrst, very difB- ciilt, but continuing to walk makes it easier,

" Audible crackling of the ankle when walking— ankle was sprained two years ago.

Sudden, violent, stabbing, piercing pain from the metatai'sal bones through the toes, while walking.

Tearing pains in the left foot, particularly in the tarsal bones.

Feet, pains; underpart; hollow of the foot; soles of the feet.

Severe painful tenderness and bruised feeling in the soles' of the feet; knee to the great toe stitches.

Painful cramp of the limbs; involuntary contractions and stiffness of the limbs ; staggering gait, on account of gen- eral weakness of the muscles; paralysis; atrophy of the

" Chronic, rheumatic and arthritic affections without fever. Jerkinff, stiiokmff, tearmg,J!/yiiig pams. retvmvmg at regular

iraervaU, for a long time.

" Rheumatism, either without fever or with slight fever.

" Tearing in the limbs, with herpes of the face.

" Tearing in all the iimbs, coming and going, now in one and

again in another limb; sour belching, and passage of

much sour-amelling flatus; cold feet; stool not increased,

but accompanied with tenesmus. " Elieumatism and gout; after the relief of the acute and

inflammatory conditions, to be applied externallv. with oil

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108 BI-BULPHIDE OF

ot almondsj or, when the sufferinga are great, to be taken internally.

' Gouty swellings when not of too long standing.

Sleep EN

Great sleepiness the whole day, but at night restless sleep.

Restless sleep, with continual rolling about in bed; particu- larly with the head.

Sleeplessness, disi/wrbed dreams, starting as from fright, fol- lowed daring the day by lassitude, want of energy.

Good and long sleep during the night.

Fever EN

Heat of the whole body, with slight headache, followed by great debihty, succeeded by sleep.

Coldness, with succeeding burning pain.

Coldness of the legs, with general warmth of the upper part of the body.

Cold face; coldness in mouth; cold extremities.

Pulse diminished to 53 beats; pulse, 90-93.

Strong pulse; spasmodic pulse.

Skin EN

" Itch and herpetic diseases.

"Herpes phlycttenodes covering dorsal surface of the hand; vesicles appearing on a red, inflamed and swollen basis; partly close together, but mostly separated irom each other. They contain an opaque, yellowish fluid, which is discharged, and forms thick, yellowish scabs; sometimes the discharge excoriates the surrounding parts and pro- duces violent itching.

"Impetigo; pimples which form scabs, in the popliteal space and on the dorsum of the foot and hand.

" A tetter-like eruption on the left cheek, for more than tw'o years, jjrodueed through scratching with the finger nails; spreads, and is covered with yellowish-brown scabs, dis- figuring the lace; almost unbearable on acount of con- tinued itching.

'Herpes exedens; together witli constipation and alternating of cutting pains in abdomen and flatulency; drawing and tearing in the limbs, and particularly in the head.

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bkomitpe of ammonium. lOy

Itching on both thigha, right side of the back to the region of the kidneys, and on the right forearm, which neeeseitatea scratching. On inspection, small, colorless pimples aro seen, which, on scratching, are more irritated, and through the friction thej redden, get points, and finally form an itch-like eruption.

Nodules on scalp, pustule on eyelid, eruption on nose and face.

" Slight burning of the left hand with boiling water; bright redness without much pain or swelling.

° Wrist joint was scalded with boiling water, several days ago; wrist much swollen, blisters partially opened.

BROMIDE OF AMMONIUM.

{Ammonium Bromidum.) Phakmacologt

This aalt may be prepared by dissolving Bromine in ■water of Ammonia.

The liquid becomes heated, Nitrogen escapes with effervescence, and the solution assumes a slight yellowish color, in conse- quence of an escesB of Bromine after saturation.

After evaporation the Bromide is obtained in four sided prisms, sometimes crossing each other at right angles.

A better method than this is by adding to Bromine and water a sulBcieut solution of hydrosulphate of Ammonia to discharge the color.

Altering to Be]>arate the sulphur, and then evaporating to dryness.

Soluble in 1.5 parts water, and in 13 parts alcohol.

It is incompatible with acids and acid salts.

Oppicisal Preparatioks

Mother-tincture;

(prepared bydlssolTlng one part in nine parts distilled water).

Dilutions In water up to the 8x, afterwards with alcohol,

AifAi.oatTEB

Bromidm of Potassium, Bodium, Lithium, ( Jhotera, Spongia, SeoaXe, TIatilago.

( ?)

Head EN

* Sensation as if a band were tied around the head, pressing

the hardest Just above the ears. *Pain in right side of head, near the eye, as if a nail were

driven in. " Shar]) pain in left side of head.

In cases where there is suspicion of the existence of conges- tion of the base of the brain, and still more of congestion of the spinal cord, or its meninges, the Bromide of Ammonia is preferable to the Bromide of Fota^sa. {Brown Fi&quard^

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110 BEOMIDE OF AMMONltTM.

* Headache from congestion of tlie brain.

"Epilepsy, when the predominant symptom is intense conges- tion of the brain. {Brovm, Seqtuird.)

° Oerebro- spinal meningitis; in the congestive stage. {Sale.)

Eyes EN

° Pain around both eyes, into the head.

" Right eye full of white, stringy mucus.

Loots as if a membrane were growing over the eye, like a pterygium.

Both eyes very sore and red; lids stuck together in the morn- ing.

Eyeballs unnaturally full, large.

Every evening eyelids droop, and it is painful and difficult to raise them,

"Strumous opthaimia, conjunctivitis, corneitis, leucoma, Nose.

Discharge of stringy mucus from the nose.

° Catarrh of the anterior and posterior nares, of thjiik, stringy mucus.

Mouth And Throat EN

White, stringy, tasteless mucus in the month.

Aecumulatiom of mucus in the throat.

Fauces, and top of tongue for half its length, feel as if scalded.

Stinging in fauces, inclination to cough, relieved by sneezing.

Tongue very sore, as if burnt; cannot talk or read without pain.

Throat looks mottled, as if diphtheric deposit were commenc- ing. {See Brom. Pot.)

Larynx and Trachea,

Cough caused by a secretion of mucus in the throat.

Tickling in the throat in the morning, with inclination to

Irritation of the throat, with inclination to cough.

" Sudden, deep cough, spasmodic, causing a pain in the stomach.

"Irritation of the organs of respiration and stomach, accom- panied with spasmodic cough, and even a distinct whoop, simulating whooping-cough. {OMe.)

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BROMIDE OF AMMOKIDM.

° Whooping congh, many eases. {Drs. Hurley, Oiiis.)

* Ooiigli deep, epasmodic, and very severe, and at times an interval of only a few moments, almost continnons for hours, especially when lying down at night, with a sensa- tion of tickling irritation, with heat and burning. {Hale.)

" Congh distressing, hoarse, dry, spasmodic, f^tlimatic and

exhausting, without expectoration. {Talbot. Cushing?j

Cheat.

Tightness across the chest, with pain in the chest; inclination to take a long, deep breath.

Swallowing anything cold causes a feeling of distress thp whole length of the (esophagus.

Sensation on top of right shoulder as if a heavy load were upon it.

Stomach EN

Something seems to issue from the stomach, as if it would stop my breath, causing a faint and disagreeable sensa- tion, and belching of wind, which relieves me.

Sensation as of liot air passing up the throat on the right side, though the stomach feels cold.

Back EN

Feeling as tliougb eometliing were pressed hard against tlie right kidney; relieved by pressure, but leaving a pnlling sensation.

Uteriis.

° In all forms of utei-ine hemorrhage, whether from lesions of the uterus itself, from ovarian irritation, excitation, in- flammation, or any of the various diseased or deranged actions peculiar to tlie ovaries or adjoining parts and viscera. {Griffik.')

" A'menorrhcea, dysmenorrhcea. I have used it with great alleviation of suffering. {Griffith.')

° Premature and profuse menses.

Superior Extremities.

Great lameness, with sharp pains in back of left leg, midway from the hip to the knee.

Pains lea\'e the right leg, and are felt in the left in same place.

Pains leave above the knee, and are felt below the knee, then in the ankle, then in the foot.

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BROMIDE OF IRON.

(Ferri Bromidura.)

This is obtaiftcd by heating gectly in tliirty parts water, two parts bro- mine, and one of iron filings. Wiieu the liquid lias become greenish, it is fillfired and evaporated to dryness in aa iron vessel ; and the dry maas is again dissolved and evaporated to dryness.

It is a black-red deliquescent salt, very soluble and styptic.

eoluble in water.

Opficihal Prepaeations

Tincture; mnst he made as follows: Tuke of Bromide of Iron one part, add three parts of sugar and ten of distilled water.

Dilutions, to the 8d x with distilled water ; higlier with alcohol.

Analogues

Bromide of Potaasa, Bromide of AmMonitem, Oaladivm.

(See Tlierapmitica, Vol.

II.)

BROMIDE OF LITHIink.

(Lithivm Bromid/wm.) FoABUACOLOas. — This salt may he made hy adding to a solution of iron

and bromine in water an excess of tlie Carbonate of Lithia, filtering to

separate the oxide of iron, and concentrating.

It is a very deliquescent salt; is soluble at 33" in .7 its weight of vrater, OFPicrifAL Preparations

Aqueous tincture;

(3ito 3 ix.jand dilu

tions to the 3 x with distilled water.

ANAWJOUKa

BTomidei <^ Potaasa, Ammoma, and Soda, Chloral hydrate.

Belladonna, Conium, Opium.

° Threatened apoplexy, or cerebral congestion, witli or without hemorrhage.

A gentleman who had iiad one attack, and was in conseqnence liemiplegic, was taken with vertigo, Jieadache, numbness, and thickness of speech.

One dose of thirty grains removed the symptoms in lees than half an hourl (Dr.

S.

W.

Mitchell observes that it acts quicker than the other bromides.)

° Epile-psy. When the Bromide of Potassium loses its effect, or disagrees, the Lithium salt arrests the paroxysms.

" Epileptic fit every morning on rising; (cured by ten grains twice a day.)

" Kelieved a case in which any prolonged mental exertion Unshed the face, caused intense pain between the shonl- ders, and insomnia.

° It removes obstinate sleeplessness more promptly and surely than the other bromides.

dbyGooglc

BEOMIDE or PO'IASiilllM. 113

Skin EN

It doea not cause the acne, eruptions, and sldn-ulcers of the other bromides.

BROMIDE OF POTASSIUM.

PaARMAOOLOGY

This Salt is prepared by adding a solution of pure carbonate of potassa to a solution of bromide of iron.

Tiie iron ia pre cipitaled and the bromide of potassium remains in solution, from which it is obtained by evaporating.

It forms wliite, pearly, transparent cxy& tals.

They are without Bmel!, and have a sharp saline taste resembling that of common salt, but more pungent.

Tliey are nnclianged by expos, lire to the air, and precipitate when heated.

It is wholly soluble in water, but sparingly in alcohol.

Official Prbparatioks

Aqueous tincture, { 3 i to 3 Ii,) dilutions to tlie 8 >; in dilute alcohol.

Triturations in pure sugar of milk.

Analoques: — Sromides vf Ammonivm, Sodium, LitMvm; QeUeminum, Oo/tmm, Chloral, ete.

Mind EN

Remarkable elownees of speech, and difficuJty of collecting the

ideas, and expressing them. {TumduU.) * J'rqfound mdanchoUc delusions. {J)r.

Wm.

A.

SarrmiOTid.) He imagined that he had been specially singled out for Divine vengeance, and he spent the greater part of the evening in loudly deploring liis sad fate,— tailing suddenly asleep at intervals of a tew minutes.

(./5.) He walked the room, groaning and wringing his hands; be- thought he had been accused of robbing a friend, and, that the oflieers were in search of him; with unsteady gait; hands and fingers in constant action; face pale and' pupils contracted.

(lb.) Loss of 'memory.

He forgot how to talk; for instance, when, asked what made him take so large a dose (sixty grs.) he- was fully two minutes endeavoring to form a reply, and then was obliged to give up the attempt, with tlie remark- " I can't." {/5.) Amnesie aphasia, — there was no difficulty of co-ordinating the' movements of the tongue, so as to articulate distinctly any word he was told to pronounce, (-/i.)

dbyGooglc

114 BEOMIDE OF POTASSIUM.

Gloomy ideas relative to his present and future condition,

'with weeping, moaning, and wringing of hands.

(/S.) She fancied tlie boarders in the hotel insulted lier.

( Van

Seren.) Imagined tiie weekly bills of tlie landlord were the evidences

of a conspiracy got up against her father. (li.) While standing on the guards of the boat she suddenly gave

a loud shriek, and declared she had seen her brother fall

overboard, {li.) Profound depression of spirits, with melancholy delusions. (75.) She is very absent-minded, low-spirited and childish. {Ham,-

mond.) Mental depression, with, feeling of approaching death and

great weakness, {Thomas.) Feebleness of intelligence. {Pletser.)

Decided lack of will and mental activity. {Srown Sequard.) ° llemoves the delusions during and after delirium tremens.

° Acute mania, with fullness of the blood-vessels of the brain.

"Frightful imaginings at night (in pregnant women during the latter months); they are under the impression that they have committed, or about to commit, some great crime and cruelty, such as murdering their children or husbands. {Ringer:)

' I^ight terrors of children, (not from indigestion,) with screaming, unconsciousness of what is occurring around them ; cannot recognize, nor be comforted by their friends; sometimes followed by squvntin-g. {liiti^er.)

° Somnambulism in children. (/5.)

" Slie is very fretful, crjing at trifles, constantly brooding over t!ie loss of a daughter; is almost crazy.

From fretting, loss of rest, and want of nourishment, is seized with nervous dysentery.

Cured by bromide of Potassiu7n, seven grains, every two hours. {Garo.)

" Spasms, from emotional or moral disturbances. {Srowne.)

" Puerperal mania. (Sale.)

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BROMIDE OF rOTASSlUM, 115

° Delirhim tremens, — not so good in the acute attacks of

mania as in the " nervousness " whicli precedes it, {Beghie.') " G-reai despondency — in men and women,- — tliej "feel as if

tliey should go oiit of their minds." {Ringer.) •^Deep depression, with painful delusions, with persistent

sleeplessness, and dread of impending destruction of all

near to her. {Beghie, Wmselhtaft.') Insanity, disappeaiing on suspending the nae of the drug,

{HaTnmond^ Delusions tliat lewd women had got into his mother's house. He imagined he was pursued hy the police, (/J.) He imagined his lite was threatened by members of his

family. (/5.) He believed he had thousands of dollars sewed up in his cloth-

ing. (/J.) He appcjired like a drunken man, except that h s 1 ice was very

pal>'-, pulse sixty, skin cooi, and pupih contiActed. (/S.) Manner exciting and rambling, his hands constantly busy,

either fumbling in hie pockets, tj ing his shoes picking

threads from hie clothing, oi in seatching ti i the gold

which he imagined was concealed in the hning of his

coat. (/6.) His character had undergone a ladical change, frcm having

been frank and bi'ave, he had become excessively timid

and suspicious of every triiiing circumstance (-^5.) He several times attempted to throw himself from the window,

and battered down a door witii an axe, in order to'escape

from some imaginary danger. (/S.) Her memory was absolutely destroyed; she could not recollect

the simplest things, and even forgot her own name and

that of her husband, though reminded of both an instant

before. {Th.) Frequently she would burst into tears for no cause whatever,

and often from purely imaginary causes, (/5.) Incoherent, full of delusions, of no fixed character, and Remarkably depressed in spirits. (/S.)

(Tliia was tlie most prominent symptom.) She had the erroneous idea that she was deserted by all her

dbyGooglc

116 BROMIDE OY POTASSIUM.

friends, and as a consequence, she passed all lier waking

moments, which were not many, in tears. {lb.) A fixed delusion that her child was dead; she declared she

saw it dead before her; and when it was brought to her,

siie refused to acknowledge that it was hers, or had any

resemblance to the one she imagined was dead. (/J-) M'ist intense Tiielanc/ioh/, attended with fits of uncontrollable

weeping, in a man. (/5.) Positvae delusions of various kinds.

Brain. It lessens the amount of blood circulating within the cranium

and prodiices a shrinking of the brain from this cause.

{Hammond.') Heaviness of the head, with confusion of the head. {Pletser.) In a case of epilepsy, caused by cerebral-ansemia, ea«h dose of

20 grs. caused an attack. {Swimnond.) Vertigo, both slight and extreme, with dullness ot the head.

{Noac.) Drooping of the head ; difficulty of holding it erect {Broivn

Sequard.) ° The flushed face, the throbbing of the carotids and temporals,

the suffusion of the eyes, the feeling of fullness of the

head, all disappear, as if by magic, under its use. {Sam,-

Tnond.) ° Violent headache, from concussion of the brain. {Ih.) ° Mercurial headache. {lioierteaii.) ° ConvnlBions— during acute meningitis, after the inflamation

has declined, leaving serious damage. {Singer, Hale.) ° Delirium tremens/ it relieves the delirium (not furious)

removes the delusion, and produces sleep. [Beghie, Hale.) " Bad results from overtaxing the brain by intense study; too

close attention to business; grief; anxiety. {-/5.) ° Calms excitement, removes the giddiness, noises in the ears,

and perversions of tlie external senses from diseases of

the brain. (/5-) ' Cerebral irritations during cholera infantum; pupils dilated,

eyes simken, eyeballs moving in every direction witlioiit

taking any notice; feet and hands blue and cold; pulse

dbyGooglc

BUOMIDE OF FOTASSIUM, 117

imperceptible.

Fifty cases treated — no deatlie.

Dose one-half grain every honr. {I)r.

Caro^

"Head hot, feel as If in a furnace, with coldness and chills, etc., etc See "Abdomen." {C<wo.)

" A feeling of " lightness " and exhilaration takes the place of heaviness and depression, {Simpson,)

"Incipient hasil^ir m&ningitis. A delicate thin female child aged five years, had complained for several weeks of sevei'e headache, Tiearly all the time, worse at night. She would play a tew minutes with other children, then lie her head down on a ehair or other support, and cry with the head- ache. She grew weak, emaciated, dull, heavy-eyed; had no appetite; did not sleep well nights; when sleeping it was disturbed by groans, grinding of tlie teeth, starting up as if frightened; complains of terrible headache; tongue clean; pulse 90 to 100, quick and wiry; constipa- tion; scanty urine, and too much heat about the head.

A careiul honi(eopathist had given Belladoima, Hyocia- mus, Oina, Bryonia, and other apparently well chosen remedies, without effect." I at first gave Belladonna, 200,, then Sulphur, 300th, which mitigated the pain a short time. Agaricus 3d was tried without much effect, i^inally Kali hrom,. one-half grain every thi-ee hours for a few days.- — no perceptible improvement; then one grain every three hours, when decided improvement in all respects set in, and in three weeks she was quite well.

As soon as decided improvement occurred the medicine was given at longer intervals. [Ilale^ Eyea.

Sight impaired, weak vision, with greatly contracted pupils.

Diminution of sensibility in the occular conjunctiva, so that the finger may be passed with impunity over the surface of the eyeball without causing winking. {Twmhull!)

Weak sight, wi^h, intoxication and deafness. {iStille.)

Dilated pupils, with extreme vertigo and confusion of the head. {Ifering.)

Pnpils prominent. (If^oac.)

dbyGooglc

118 EEOSUDB OF IVTASSIUM.

Pupils dilated, and contract very sliiggislily under the influ- ence of a very strong light. {T'urniull.)

Lusterless ejes. {Basiro.)

" Squinting, after niglit-terrors of children. {Smger.')

° Dilated pupils and sunken eyes (in cholei'a infantum.) {Caro.)

" Eyeballs moving in evei-y direction. {lb.)

° Pliotophobia ^s a collyrium, 3 parts to 30 of water.) {Coth- hron a/nd Eosignol.)

Ears EN

Diminution of hearing. {Hammond.)

° Einging in the ears. {Begbie.)

° Erythematous swelling of the nose.

Mouth— T on gue— F ances.

Loss of speech.

ATnrtesio aphasia. [Ifam^mond.) Much difiiculty in talking.

(lb.) Slight redness of the buccal and pharyngeal mucous mem-

branes. {Fletser.) Slight traclieal and bronchial catarrh. (75.) The lauces do not cowtract when touched, tickled, or even cut

with instruments. {lb.) ° Tongue pale and cold. {-lb-) " Tongue red and dry (in cholera infantum.) {Tb.) ° Infants are choked every time they attempt to drink fliiids,

although they can swallow solids without difficulty, — no

malformation of the throat. {Ringer.) " Hot, dry mouths of teething infants. {Oat-o!)

Pace. A papular rash on face and nose, with heat and itching. {Mc~

Ovegor.) Successive crops of small boils in the face, with troublesome

itching. {Basire.) Acne-like eruption on the face, neck and shoulders. {Browt

Seqtuwd.) ' Expressionless face. {Basi/re.) ° Acne, in young persons, {Hale.)

Jaws and Teeth. ° Difficult dentition of children. {Caro.) {See Broin. Oalc.)

dbyGooglc

OF POTASSIUM. ll.y

" Odontitis in children, " I have never failed to relieve the

child by its local application." (/5.) "After the first rubbing on, the gums, from being turgid,

swollen, and red, they assume their natui^al color, and a

certain amount of ease is felt. {/5.) " The salivary secretion is restored (in teething children), and

as if by enchantment, agitation, carpopedal involuntary

motion, vomiting, and looseness of the bowels disappear.

(n.)

Mouth EN

Irritation of the mucous membrane of tlie mouth and fauces, painfulness of the tongue, prominent pupils, rongh and burning sensations in the whole butecal cavity as if burnt with caustic. (.Noac.)

Increased Secretion of sahvaand mucns, (Jb.)

Short-lasting titillation in the tauces, (/5.)

A state of insensibility of the larynx and palate; the fingers may be carried to the base ■>!' the tongue, touch the amygdala and posterior nares, ^Mid tickle the uvula, with- out inducing any efibrt at vomiting or deglutition.

" Uestoration of the suppressed salivation in teething children.

*^(Etid breath; a pcKiuliar sickening odor, (/fale.)

Wliite tongue, involving tho edffes as well as the dorsum, and

not necessarily furred, with great Imiguor, sle&pmess, and

anoretda. (/5.)

G-astrie Symptoms.

Increased appetite.

(JVoao.) Thirst in the afternoon, (/i.) Repeated repulsive eructations.

(/^.) Violent nausea and efforts to vomit, with vomiting of a small

quantity of mucus, with salt taste in the mouth. (/5.) ° Troublesome pressure at the stomach after dinner. {Hering.) " Loss of appetite. {Noac.)

Liver. ° Enlargement of the liver; under the use of half a grain three

times a day, the belly rapidly assumes tho natural size.

{Magerulie.)

dbyGooglc

120 BKOMIDE OF rOTASSIUM.

Stomach EN

Slight catatrh of tlie stomach. (Pletzer^

Peculiar pressure in the region of the stomach, succeeded by

violent colic. {Hering^ Weakness of the stomach, for some time.

(75.) " Vomiting when the ganglionic system is affected. {Seghte.) " Vomiting during pregnancy. {Oei'SOy, Hale^ ° Vomiting in whooping cough. i^Dr.

Searfoot^ " Vomiting of mecoTi/ium. {Ca/ro.) ■^ Vomiting, with intense thirst.

(/5-) ° Yomiting of d/rv/nkards after a debauch. [Hale^ " Chronic morning vomiting of drnnkards.

(/J.) " Vomiting, diarrhoea, cramps, coldness and collapse in cholera

infantum.

(/5.) " Vomiting with diarrhtea of teething chOdren.

(Oaro^ " Cholera infantum, — many cases (160 cases treated); only three deaths.

(/S.)

Spleen.

" Enlargement of the spleen.

" Small tumor in the region of the spleen.

(^Turnbull.)

Abdomen EN

° Ascites of hepatic or splenic origin. ° Constipation of years continuance. (Hale.) Obstinate constipation. {Pletzer^

Sensation of warmth in the abdomen. {HeimerdingeT^ Flatulence; frequent rumbling, (/5.) Frequent soft stools, preceded by colic. (/J-) Several papescent and afterward liquid stools. (/5.) " Bloody muco-purulent diarrhea, with intense thirst, vomit- ing, eyes sunken, pnpils dilated, skin corrugated and spotted blue, body cold, tongue red and dry, pulse imper- ceptible, urine suppressed. {Caro.) ° Colic in young children; the walls of the belly are retracted and hard, while the intestines can be seen at one spot contracted into a hard lump, of the size of a small orange, and the contraction can be seen through the abdominal wall to travel from one part of the intestines to another; these attacks are frequent and excruciating;

dbyGooglc

J3E0MIDE OF POTASSIUM. 121

are unconnected with diarrhtea or constipation, but are often associated with an apthons condition of the mouth. {Ringer, Sale.)

" Periodic colic, in infants, occurring about 5 p. m. every even- ing, with the ahove symptoms. {Hale.)

° Abdomen snnicen, almost stuck to the vertebral column, in cholera infantum. {Caw.)

° Retention of tnecomum, with vomiting of all food, and obsti- nate constipation; in a cbUd three days old, cured by 1-50 of a grain every hour, {Caro.)

° Painless diarrhrea, fiiteen or twenty passages in twenty-four hours, with great chilliness, even in a hot room; burning in the chest; abdomen cold internally; pulse one hundred, weak; urine scanty, dribbling a few drops at start. "At every evacuation felt as if my intestines were sinking from me. I was restless and shaky as if from palsy." Dose five grains; after the second dose fell asleep for si.x hours, perspiring profusely. {Caro.)

° Summer complaint, or cholera infantum, is not an inflamma- tory affection, but arises from an over exGitement of the nervotis and vascular systems, and therefore the b. of p. is a specific. (/5.)

° Asiatie cholera, in the first stage, arrests the vomiting, the cramps, and the rice-water discharges; restores the secre- tion of urine; the warmth and color to the previously cold and livid skin. (Dose twenty grains every hour.) Its use should be suspended when reaction or fever sets in. {Begiie^

° Discharge of a considerable quantity of tar-like substance (decomposed blood), Iiaving a fcetid smell; accompanied with tenesmus in animals. {Jfoao.)

° Spasmodic stricture of the sphincter am,.

(Horn.

World^ Sexual Organs.

(Men.)

Diminution of sextial desire. {Huett et al.)

Absence of sexual desire, with impotence, {Ih.)

Semen is not secreted. {Pfmffer^

" Nocbumal endBsionSy with amorous dreams and erections.

dbyGooglc

123 BROMIDE OF POTASSIUM.

° Excessive sexual desires, with constant ereetiona at night

{Bale.) ° Chordee, during gonorrhcea. {!/>.) "^ Satyriasis. {TMallman.)

° Sensual and lascivious fancies and dreams, (Hale.) The anapiirodisiac power of tlie b. of p. is dne to contraction

of minute afferent vessels of the corpus eavernosus.

(Pelvet.)

Sexual Organs EN

(Women.) Abolition of all sexual feelings. {Ilale.) Loss of enjoyment during coition.

(/5.) " Nynvphoina/thia. [Bale, Couch, Samtnond, et al.') " Excessive sexual desires during the menses.

(Hale.) " Erotomania, a few days aiter the inenses.

(/5.) ° Nymphomania daring the puerperal state.

(/S.) * Voluptuous itching, tingling and irritation in the external

genital organs.

(/&■) " Epilepsy from ovarian, irritation.

" Epileptic attacks at or near the menstrual periods, (Lay

cock.) "Enlargement of the uterna ("eub-involution") after parturi- tion, with abnormal discharges. [Simpson.) " Diminished the size and alleviates the pain in fibrous tumors

of uterus.

(-Tb.) " Menstrual ailments.

Before the menses; headache/ during

the menses : epileptic spasms, nymphomania, itching.,

burning and esecitemsnt in the vulva, pudenda and

clitoris; after the menses: headache, insomnia, and heat

in the genitals.

(Hule.) "Metrorrhagia from reflex irritation, or of nervous origin.

(lb.) ° Menorrliagia at the climacteric period, ((rarrod.) ° Sterility, from excessive sexual indulgence, {Hale.) riie menses are more scanty.

Urinary Organs, In a few cases the urine contained albumen. (Pletser.) Pain in the region of the kidneys, spreading in the direetiou

of the colon ascendens; afterwards copious secretion of

Urine EN

{Noao.)

dbyGooglc

BROMIDE OF IVrTASSIUM. 123

Dimimitioii of the sensibility of the urethra. (^Caro.)

Profuse urination, with thirst. {HeTing'.)

Thin, yellowisli-white, copious iirine- {Heiinsrdinger.)

Pale, thin urine, having a peculiar f(Etid smelL {JVoao.)

Diminished secretion of urine. {lb.)

° Convulsions from Bright's disease.

"Abnormal irritability of the urinary passages. (/5.)

° Nocturnal involuntary emissions of urine. {ITewaoti.)

" Suppression of urine in cholera infantum. (Caro.)

milUtua, (Two cases.) Symptoms: emaciation; 'dn cold and dry; pulse rapid and feeble; tongue red and tender; gumsspongy and bleeding; thirst excessive; appetite voracious; bowels constipated; wrine pale, frequent, large quantity, of high density, and loaded with sugar; liver tumid and tender. (Twenty gre, b. of p. three times a day.) Ail the symptoms disappeared in six weeks; no relapse. {Beghie.') ° Neuralgia of the neck of the bladder. {Pfeiffer.) ° Spasmodic affections of the neck of the bladder. (Hale.) ° [The b. of p. is found in the urine two weeks, even four weeks, after it was taken in an animal.] {Boh&rteau.) Iiarynx. Lose of sensibility in the larynx.

Hoarseness, extremely painfuland disagreeable. {Sering,') Hacking cough, with dullness and confusion of tlie head. (Ih.) " Hyperaasthesia of the laryngeal nerves. [Mayhofer.) ° Whooping-cough, v/iicompUeated by other affections. " Laryngismus stridulus, uncomplicated. {Mayhofer.') " Diphtheria, with quick pulse; fever; dry tongue; offensive breath; highly injected and dusky-red fauces; with patches of wash-leather exudation on tonsils or pharynx. {Snelling, Belcher^ ° Follicular and catarrhal lai-yngitis, {Mayhofer, of Nice.) 'Membranous croup, with whitish exudation. [Kali bi*'li.,

when yellow.] (-/S-) [A solution of b, of p. dissolves false membranes.] {Laboul-

hene.) ' Whooping-cough— -the spasmodic action disappears in about

dbyGooglc

124 BKOMIDE OF POIASSinM.

five days, leaving a simple broncliial catarrh. It r

tlie anxiety and the vomiting; improves the appetite, and

increases the strength. [De Beavfort^

* N&foo'us cough during pregnancy, threatening abortion ; the cough was dry, hard and almost incessant.

Anscnltation or percussion gave no evidence of disease of the head or lungs.

Opium, Belladonna, etc., were tried for two months, without benefit.

Bromide of Potassium,, thirty grains a day, cured in two days.

(ZV.

Oerson.)

° Spasmodic croup, as the chief remedy, almost to the exclu- ., sion of other articles. {Dr.

G.

T.

ElUot, Hale.)

Chest EN

Slight bronchial catarrh. (Pletzer?)

Tightness of breathing. (JVWo.)

Violent congestion of blood to the respiratory organs, occa- sioning spitting of blood.

" Asthma of a nervous origin. {Begbie^

° Breath hot and hurried, with burning in the ehest. {Caro.)

~ ~ " , with nervous headache, and want of sleep,

'■)

isthma of children.

In one case, great dyspntea, no sleep, urine suppressed, general tedema, six grains every two hours; remarkable improvement now set in; the dyspnoia subsided; the Itvidity of the fa<;e and (edema disappeared, secretion of urine returned, and sleep was obtained; cured in seven days.

In another case the result was similar.

It did no good in old Bsthmatics, (Hehr.) Browne.)

"The respirations are affected in a secondary manner only." It appears to be influenced only mechanically, that is to say, its muscles are paralyzed, like tlie other muscles, more or less rapidly; early in frogs, and at the moment of death in birds and rabbits, {Demowrette and Pelvet.) Iiower Extremities.

Debility of lower limbs; step tremulous and uncertain. {StiUe.)

Loss of sensibility in lower limbs; pinching and burning causes no pain, (Paehe.)

dbyGooglc

OP POTASSIUM. 123

Extremities cold, pulse slow and very weak. {Tv/mhull^

° Legs and feet cold and blue, and on being touched would

leave the white impress of the fingers for more than

twenty-five seconds, — in cholera infantum. {Oaro^

Sleep EN

Extreine drowsiness.

Tendency to coma.

(Hainm.ond et al.)

She slept all night, and would often fall asleep iu her chair,

and in most uncomfortable positions. (/5.) H.e falls suddenly asleep at intervals of a few minutes, (/i.) A kind of stupor resembling that of the first stages of typhoid

fever, (Basire.) "Deep, prtrfound and quick slumber, (from twenty to thirty

grains). {Ilaimnond.) " Obstinate insomnia, in case of mercurial poisoning. {Jioh.

erteau.) " Sleeplessness during convalescence from acute diseases,

_ (Begbie.) ° Night terrors of children; horrible dreams. (/5.) ° Waking yitli severe headache, in a child. {Kale.) "Grinding of the teeth during sleep, with moans and cries.

, dark red eruption made its appearance on the right elbow, from which it diffused itself over the whole body, rapidly becoming pustular.

The pustules were very numerous, isolated, distended with pus, and frequently en]>ped, so as to present a very fair counterfeit of the eruption in discrete variola.

They were generally some- what oval in outline, and varied from two to four lines in their longest diameter.

Wlien maturation liad taken place there was no apparent base nor areola, and the inter- venina skin was healthy.

If not interfered with desicca- tion lolJowed, and scabs were formed and thrown oif, and leaving the integnment beneath reddened but sound.

The pustules continued to appear for four or five weeks; the discoloi'ation of the skin, however, remained for as many months. {Dr.

J.

G.

Merrill.) An eruption similar to discrete variola; a dark red elevated eruption, rapidly becoming pustular; pustules very nu- i, isolated, distended with pus, often cup shaped.

dbyGooglc

126 BEOSiroE OF

Heart and Pulse.

The rainnte blood-vessels contract immediately in the region of injection, and later throughout the organism, and the contraction is succeeded by dilation. {Pelvet.)

The heart alone survives many hours (in animals); when it stops, its irritability can be again aroused for some instants, to disappear at last totally. But from the com- mencement of the physiological or toxic action, the capillary circulation is diminished, and the pulsations of the heart are retarded. i^Damoeyette and Pelvet^

" Pulse imperceptible, with coldness and collapse. {Ca/ro^

° Pulse 100, weak.

Pulse 50, small and feeble.

(Tb.)

" Neuroses of the heart. {Sale.)

° It has a sedative effect upon the action of the heart.

Temperature EN

The temperature of the body was reduced one or two degrees centigrade. {Pletser^

The temperature is sensibly lessened in warm-blooded animals first, and during many hours in the region injected, and afterwards throughout the organism. The phenomena depends upon the diminution of the capillary circulation, at first local, afterwards general.

° Body cold; skin corrugated and mottled. {Caro.)

"Shivering with cold, and cold skin, although the child was covered with mustard plasters. (/J.)

Generalities EN

The gait became staggering; false steps became frequent.

"Weakness of tlie muscles of the arms — ^!mt no vertigo. {Pletzer.)

It paralyzes the nerves of the spinal cord. {lb.)

Intoxication, with loss of sight and hearing. {Stille.)

* Epilepsy from large doses in a case of cerebral ansemia. {JTa7n.m,ond.)

Unsteadiness of gait; he was frequently taken for a drunken man ; was once arrested for supposed drunkenness, [limn- iRond.)

Well marked numbness throughout the body, and very decided diminution of sensibility.

Almost constant twitching of the fingers and a busy occupa- tion of them in matters of no importance.

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BROMIDE OF POTASSIUM.

Unable to stand or walk; fa«e ashy pale; pupils contracted; loss of meiiioiy. Great M'eakness of the extensors of the legs and feet.

Vertigo, fainting and nausea.

Very emaciated, weal;, and of a peculiar pallid color. {Turn- hull.)

As an agent for lessening reflex excitability, exceeds all other remedies. {Pletser.)

" Neuroses involving the brain and accompanied by convul- sions, (li.)

"Mercurial trembling. {Roberteau.)

° Zead poisoning. (/5.)

* Infantile conmtl&tona, during teetl ing, whooping cough or

laryngismus stridulus. Spasm of the glottis; it prevents the recurrence of the spasms. {Ilvnger, Hale.)

* Epilepsy, chiefly grand mal; rarely useful in pelyit mal. Restless and shaky, as if from palsy. (Caro.)

It diminishes the abnormal vascularity of the great nervous centres.

Temperature EN

The temperature of the body was reduced one or two degrees centigrade. (Pletser.)

The temperature is sensibly lessened in warm-blooded animals first, and during many hours in the region injected, and afterwards throughout the organism. The phenomena depends upon the diminution of the capillary circulation, at first local, afterwards general.

"Body cold; skin corrngated and mottled. (Caro.)

° Shivering with cold, and cold skin, although the child was covered with mustard plasters. {-lb.)

It mitigates those convulsive movements and spasmodic twitchings, which are the results of the rapid conversion of sensory impressions, or of morbid reilex action tlirough the medulla oblongata. {C. Browne.)

" Quotidian ague after qninine had been given for two weeks without result. "The sweating stage was unusually pro- tracted and exhausting," " A full dose every three, hours daring a remission, cured." {Segiie.)

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128 BEOMIDE or rOTASSIOM.

* It removes pathological deposits of fetty matter (inlj, while the iodide removes normal adipose matter. {Simpson.)

It diminishes the r^^ea; excitability of the nervotis centi-es. (Broton Sequard.^ The functions of organic life are not disturbed. {Hu^t^

" Epilepsy — especially occurring at or near the menses. {Lay- cock.)

/ may be arrested by it, but returns when this drug

Pa/ralyds agitatis.

° Trembling sensation throughout the whole body, {Hale.)

"Tetanus; a boy 15 years old, from suppuration of finger nail and exposare to cold by sleeping on the grass.

Attacked October gth.

Discharged September 10th.

Dose 20 gre. every two hours nearly all the time, A few days took 20 grs. every hour. [B.

Browne.)

° Chorea in a female.

The tongne protruded with a jerk; muscles of the face, right arm and legs in constant jacti- tation, quite violent.

Eight grains every three hours; cured in two days. {Dr.

HuTne.)

" Chorea in a female, of several weeks.

Unable to dress her- self or work, and could hardly speak.

Face, ann and leg of right side affected.

Ten grains every four hours cured her in tliree days. {Dt.

Huine.)

": Sym^oms from an affeoUon of vaso-motor nerves, namely:

1.

Occasional sudden paroxysmal teeling of "numbness," a term employed by some to denote the sensation of " piua and needles ;

" by others that of " deadness " and " weak- ness," and by a third group an " indescribable feeling of something wrong."

ir. A feeling of "largeness," or "ae if the limb were swollen," there being at the time of its occurrence no change in the size of the extremity.

ni. The occurrence of " aching," of " uneasiness," or of actual "pain," the latter not very severe.

IV. The feeling of " coldness," and occasionally, the obvious fiict of coldness.

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OAOTCS GRAND! FLOKU8, 129

7.

The fact of sudden "weakness," sometimes termed a "par- alyzed" feeling; the patient being unable to retain the grasp of an object, and hastily putting it down, or allow- ing it to fall.

At such times the muscles do not respond readily to the will; the co-ordination of movement is defective.

Such acts as writing or needle-work have to be discontinued, and generally such patients rub the limbs bv, as it would seem, an almost instinctive impulse.

VI.

The occurrence of sensations allied to cramp, or that of actual cramp, with varying amounts of pain. {■!.

Russell Heynolds.)

[Aconite, Gelseniinum, Platinum, Pulsatilla, Ljcopodium, Veratrum album, and Oalcarea carb. have many of the above symptoms, {Hale,')]

"The symptoms due to large doses of the Bromide of Potas. siura may be stated as follows, in the usual order of their occurrence :

Contraction Of The Pupils EN

2, Drowsiness. 3.

"Weakness of the arms and legs. 4.

Depression of mind, 5, Fail- ure of memory. 6, Delusions.

The first three of these are, I think, usual accompaniments of an active dose of the medicine.

They simply show a sedative effect due to cerebral ansemia.

In adults they never follow a less dose than ten grains.

Doses of five grains produce no obvious effects.

Ho permanent diffi- culty results from very large doses." (Hammond.)

Dr. Hammond asserts that to a condition of cerebral anwmia most of the obvious phenomena which follow its adminis- tration should be ascribed.