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Nitri Dulcis Spiritus

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General

Spiritus aetheris nitrosi. Sweet spirits of nitre.

This substance is essentially a solution of aethyl nitrate (C 2 H 5 NO 2 ).

Authorities. 1 , Lembke, Zeit. f. Hom. Kl., 4, p. 145, took repeated doses of 5 to 30 drops; 2 , same, Neue Zeit. f. Hom. Kl., 17, p. 36, took repeated doses of 10 to 40 drops; 3 , same, subsequently repeated the proving; 4 , same, subsequent proving with doses of 10 to 60 drops; 5 , Brown, Pharm. J., 16, p. 455, effects of inhalation of vapor of "nitrous ether;" 6 , second case; 7 , third case; 8 , effects in self.

Mind

Slight confusion of ideas, [6] . Some anxiety, [6] .

Head

Confusion. Confusion of the head (soon after a dose), [1] .

Head very much confused, heavy, and hot, for three hours, [4] .

Vertigo

Vertigo, [1] , [6] .

Sensation of impending vertigo several times, soon; also, while sitting, a sensation as if the upper part of the body swayed to and fro, [1] .

Sensation in the head as if vertigo would occur, repeated several times (soon); between these attacks, while sitting, a sensation as if the upper part of the body swayed to and fro, [2] .

General Head.

A dull annoying pain is felt in the head, more acutely along the course of the temporal arteries, which continues for five or six hours (after five or six hours), [5] .

Violent tearing in the head, [4] . [10.]

Tearing in the head, [4] . Tearing pains in various parts of the head, [3] .

Drawing and tearing in the head, especially in the right side, [4] .

Drawing pressure in various parts of the head, [2] , [3] . Frequent pressure in the head, [1] .

A slight degree of swimming in the head, scarcely perceptible even when at the worst, [5] . Pressure and heaviness in the head, [4] .

Pressure and heaviness in the head, lasting a long time, [4] .

Heaviness in the head, with pressure in the forehead, [4] . Heat and heaviness in the head, soon after a dose, [4] . [20.] Stitches on the head, [3] .

Headache, continued for seventeen hours (after half an hour), [6] .

Forehead.

Confusion in the forehead, [1] .

Confusion in the forehead, on rising in the morning, with persistent pressure and heaviness, lasting several hours, [3] .

Violent boring in the forehead, [3] .

Violent persistent pain in the frontal bones, [3] . Boring in the forehead, at night, [4] .

Boring in the left side of the forehead, at times very violent, [4] .

Violent boring here and there in the frontal bones, frequently repeated, [3] .

Boring in various parts of the forehead, [3] . [30.]

Violent pressure and boring in the frontal bones, [3] .

Drawing pains in the forehead, [2] .

Drawing in the forehead and bones of the face, [3] .

Drawing and pressure in the forehead, [3] .

Heaviness in the forehead, [3] .

Pressive pains in the forehead, increasing in the evening, noticed while both walking and sitting, [3] .

Pressure in various parts of the forehead (soon after a dose), [1] .

Violent pressure and heaviness in the forehead, [3] .

Pressure in the forehead, especially violent, [3] .

Pressure and heaviness in the forehead, [2] . [40.]

Frequent pressure and heaviness in the forehead, [3] .

Frequent pressure and fulness in the forehead, [3] .

Pressure in the forehead and sinciput, with a feeling of heaviness and fulness in the head, [3] .

Pressure in various parts of the forehead, [1] , [2] . Pressure in the forehead, [2] , [3] , [4] .

Pain in the forehead, with pressure and heaviness, worse towards evening, [3] . Heat in the forehead and face, [2] , [3] .

Temples.

Boring in the temples, [3] .

Boring as with a dull instrument in the left temple, [3] .

Pressure in the temples, [2] . [50.]

Pressure in the right temple, [1] .

Pressure in the temples and frontal bone, [1] .

Pressure in the left temple, [1] .

Pressure in the temples, with a sensation of heaviness in them, [2] .

Pressure inward as with a dull instrument in the right temple, [1] .

Vertex.

Stitches on the vertex, [2] . Pressure and heaviness in the sinciput, [3] .

Drawing in the scalp, with pressure in various parts of the skull, [1] .

Horripilation on the scalp, [1] . Occiput.

Heat in the occiput (soon), [3] . [60.]

Pressure in the occiput, [1] , [2] .

Heaviness in the occiput, with heat, [1] , [2] .

Eye.

Dull appearance of the eyes, [5] .

Stitches in the eyes, [3] .

Lids.

Visible twitches in the right upper lid, [3] .

Frequent twitching in the margin of the right upper lid, [1] .

Stitches and burning in the lids and their margins, [3] .

Burning in the margins of the lids, [3] .

Stitch in the upper lid and above the right eye, [3] .

Lachrymation, [1] . [70.] Stitches in the eyeballs, [3] .

Black spots and rings float before the eyes, always after a dose, with heat in the head and contracted pupils, [4] .

Ear.

(The left ear is closed, without swelling or pain, lasting more than an hour; it seemed to be the commencement of a violent coryza that developed the same day), [1] . Pressure behind the ears, [2] .

Pressure in the left mastoid process, [1] .

Stitches in the left ear, [4] .

Face

The first observed effect is a bluish-purple color which the lips take on; this occurs even when the vapor is very dilute, and it may exist quite unconsciously and without any bad effects whatever; after being exposed for one or two hours to a rather diluted vapor, or after exposure for only a few seconds to a very partially diluted vapor-after it may be only three or four natural inspirations-the lips assume a deeper purple tint, the eyes a dull appearance, and the whole countenance has a ghastly, dirty-looking pallor about it, as if smoked all over; the hands, more especially beneath the nails, partake of the purple color; afterwards the hands are of a leaden blue or purple color, [5] .

Visible twitching in the middle of the left part of the upper lip, along the margin, [1] .

Boring in various parts of the bones of the face, [3] .

Boring in the bones of the face, [2] . [80.]

Pressure in the bones of the face, [3] , [4] .

Stitches in the muscles of the face, [3] .

Frequent stitches in the muscles of the face, [4] .

Pressure in the bones of the face, worse on the right side, [4] .

Sensation as of a cloud over the upper portion of the face, [1] .

Stitches in the masseter muscles, [2] .

Drawing stitches in the cheeks, [3] .

Drawing in the right upper jaw, [1] .

Violent boring in the lower jaw, especially in the angles, [3] . Drawing in the upper jaw, [2] .

Teeth

[90.] Tearing in the upper teeth, [2] .

Tearing in the lower teeth, [3] .

Tearing in the upper canine and incisor teeth of the right side, [1] .

Tongue.

Cutting deep in the forepart of the tongue, [1] .

Drawing in the lower teeth, [3] .

Burning in the tongue, [3] .

Sticking and burning in the tip of the tongue, [3] .

Sharp stitches in the tongue, [1] .

Stitches deep in the mass of the tongue, [1] .

Violent stitches in the tip of the tongue, [3] . [100.] Stitches in the tip of the tongue, [1] , [2] .

Fine stitches in the tip of the tongue, [1] .

Stitches in the tongue, [1] , [2] , [4] .

Very flat odor in the mouth, [1] .

Saliva.

Profuse clear saliva collects in the mouth after a dose, [1] .

Much thin saliva in the mouth, [2] .

Much thin saliva with a constant salty taste on the tip of the tongue (soon after a dose), [1] .

Profuse mucus constantly in the mouth, with a taste of lye, [1] .

Much mucus in the mouth, [2] .

Sensation like that preceding nausea, together with increased mucus in the mouth, [1] . [110.] Salty taste on the tongue and salivation, [1] .

Throat

Constant dryness in the throat, [1] .

Cramp extending from below upward in the oesophagus, [1] . Increased accumulation of mucus in the throat, [1] .

Stomach

Violent paroxysmal cutting pain deep in the pit of the stomach, together with flushes of heat and general hot sweat, [1] .

Peculiar sensation of aching in the pit of the stomach, [1] .

Heaviness, fulness, and oppression in the pit of the stomach, [1] .

Pressure in the stomach, extending up the oesophagus, [2] .

Pressure in the stomach, [1] . Pressure in the stomach, as from a dull instrument, aggravated by deep inspiration, pressure, and keeping the body erect, relieved by bending inward the abdomen, which is not at all soft; after half an hour the pain increased, became cutting, extended to the umbilical region, and was aggravated by even slight inspiration; the pain continued four hours; was very much increased by eating, when it became cutting; there was much accumulation of gas in the abdomen, after the evacuation of which the pain was relieved, [1] .

Eructations. [120.] Eructations of air tasting of the drug, [4] .

Eructations of air, [1] . Sensation of qualmishness in the pit of the stomach rising into the mouth, with much mucus in the mouth, [1] .

Vomiting at an early stage, not either severe or persistent, [1] .

Nausea. Frequent nausea, [1] .

Nausea, with some sensation of qualmishness in the stomach, accumulation of saliva and hunger, [1] .

Abdomen

Many noises of gas in the abdomen, [1] .

Rumbling in the abdomen, [2] .

Rumbling in the abdomen and pressure in the umbilical region, [2] .

Some pressure in the epigastric region, [2] . [130.]

Sudden stitches in the left side, below the navel, extending towards the bladder, [1] .

Urinary Organs

Urethra.

Violent cutting in the tip of the urethra, [3] .

Stitches in the tip of the urethra, [1] , [3] , [4] .

Violent stitches in the tip of the urethra, [3] .

Numerous stitches in the tip of the urethra, [3] . Violent stitches in the tip of the urethra while urinating, [4] .

Frequent stitches in the tip of the urethra, [3] .

Micturition. Frequent inclination to urinate, [1] , [2] .

Much desire to urinate, [3] . Frequent micturition of profuse urine as clear as water, [4] . [140.]

Frequent painless micturition, [4] .

Urine

Frequent micturition of yellow urine, [2] .

Urine very clear in color, with frequent desire, but not increased quantity, [1] .

Urine passes frequently, [2] .

Urine yellow during the whole proving, not increased in quantity, [2] .

Urine scanty, [1] .

The diuretic action was not apparent until twelve or fourteen hours after exposure to the vapor, [5] .

Diuretic effects (within an hour or two), [6] .

Sexual Organs

Stitches in the glans penis, [1] .

Respiratory Organs.

*Breathing slow and regular; on walking a short distance it becomes very hurried; if the attempt is persevered in it becomes quick, difficult, and painful, and a most distressing sense of painful constriction is felt underneath the sternum , [5] . [150.]

Tickling in the larynx, with short dry cough, [2] .

Tickling in the larynx, with a dry cough, in the evening, [2] .

Tickling in the larynx, causing a dry explosive cough, [1] .

Much sticking and tickling in the larynx, with thin saliva, [1] .

Numerous stitches in the larynx, in the evening, provoking cough, which was dry, [1] .

Stitches and constriction in the larynx, [1] .

Short dry cough, [1] . Short dry cough, several mornings, [1] .

Chest

Cramp rising up in the oesophagus, with intermitting pains extending to the upper portion of the wall of the chest, [1] .

Pressure moving about in the upper portion of the wall of the chest, [1] . [160.]

Pressure above the lower portion of the wall of the chest, [1] .

Sticking and pressure in the left wall of the thorax, [3] .

Pressure above the lower portion of the thorax, [2] .

Pressure in the upper part of the thorax, [2] .

Stitches in various parts of the thorax, [3] . Front.

Violent beating and pressure behind the sternum, while walking, [3] .

Dull pressive sensation low down in the sternum, as if in the oesophagus, [1] .

Pressure in the sternum, [1] , [2] .

Sides.

Sticking pain in the upper part of the left wall of the chest, without affecting breathing, [1] . Intermitting sticking pains in the upper part of the wall of the left chest, afterwards in the right, without affecting respiration, [1] . [170.]

Pressure in the upper part of the left wall of the chest, disappearing and returning without affecting respiration or motion, [1] .

Pressure in the left wall of the chest, coming and going several times without being affected by respiration or motion, [2] .

Stitches in the right, then in the left wall of the chest, not aggravated by inspiration, [2] .

Heart And Pulse.

Heart

The sensation of violent beating in the heart occurs frequently in the evening on lying down in any position, lasting only a moment, [3] . If walking is persevered in the heart makes itself felt by its rapid, tremulous, tumultuous action, [5] .

Some violent beating of the heart, [4] .

Violent beating of the heart, at times with a feeling of pressure, [4] .

At times while walking a peculiar sensation in the heart, like violent beating; this symptom occurred very frequently during the day, [3] .

Pulse

The pulse during the first quarter of an hour after 25 drops was irregular, the beats generally fuller and harder, [1] . The pulse remained unchanged for half an hour, except that it was fuller and slower than usual, [2] . [180.] Pulse weak and quick; on walking a short distance it becomes very quick, [5] .

Pulse frequent, for half an hour (after 20 drops), [1] . Pulse rather fuller and somewhat slower than usual (half an hour after 10 drops), [1] .

Neck And Back.

Violent pressure in the nape of the neck and cervical vertebrae, [3] .

Stitches here and there in the thorax and back, [3] .

Sensation as if hot water were creeping through the back from below upward, lasting a quarter of an hour, [1] .

Pressure and stitches in the region of the spine, [2] . Drawing in various parts of the back, [2] .

Stitches in the final processes of the vertebrae, [3] .

Numerous violent stitches in the vertebrae, [3] . [190.] Drawing in various parts of the dorsal muscles, [1] .

Stitches in the spinous processes of the middle dorsal vertebrae, [1] .

Violent sticking in the spinous processes of the last dorsal and upper lumbar vertebrae, [1] .

Pressure in the lumbar muscles and hip-joints, [4] .