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Senna

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General

Cassia obovata, Colladon; (C. Senna, Linn.); also C. acutifolia, Delile; C. Lanceolata, Lam.

Senna, the Arabian name; Senna Alexandrina.

Natural order , Leguminosae.

Preparation , Triturations of the leaves. (The active principle, Cathartic acid and its salts, is not soluble in Alcohol).

Authorities. 1 , Wigan, Lancet, 1846, 1, 28, three children poisoned by Senna tea; 2 , Bley and Diesel, Pharm. Journ., 1850 (Pharm. Cent. Bl., 1849, No. 8); 3 , Smith, Pharm.

Journ., 1868-69, p. 315, effects of repeated doses; 4 , Bourgoin and Bouchut, Journ. Pharm. Chim., XII, 305, fourth series, effects of 5 to 15-grain doses of the "mucilaginous matter in Senna" in fifteen children; 5 , same, a child of twelve took the mucilaginous matter, followed on third day by 10 grams of fluid extract; 6 , same, 15 grains of fluid extract in a child of fourteen; 7 , same, 6 to 30 gram doses of fluid extract in thirty-one children; 8 , Berridge, Am. J. of Hom., M.

M., 8, 126, Mr. --- inhaled infusion of Senna; 9 , same, Dr. B. inhaled same.

Nose

Repeated sneezing, which caused heat (especially of hands), exhaustion, and panting breathing, [8] .

Face

Livid lips, [1] .

Stomach

Nausea, lasting some time, [9] .

Three had nausea, [7] .

The so-called Cathartin, in doses of 2 1/2 to 3 drachms, caused only nausea and disagreeable eructations, [2] .

The brown resin, in doses of from 15 to 80 grains, merely caused nausea, and in larger doses, vomiting, [2] .

Some vomited, [7] . Irritation of the whole mucous membrane of the alimentary canal, extending even to the nostrils, [3] .

Abdomen

Two had griping pains, [7] . [10.]

Fourteen had *colic , [7] .

Stool

In two cases there was but one motion; in seven cases, two; in two three; in six, four; in five, five; in three, six; in three, seven.

These evacuations were yellowish, more or less abundant, and after the purgation there was neither uneasiness nor fever, [7] .

Upon seven it had a slight purgative effect, characterized in three by a single muddy evacuation, and by two to four yellowish liquid evacuations in others, [4] .

Two liquid painless evacuations, [5] .

Two *liquid evacuations, with griping pains , [6] .

Urinary Organs

In doses of 60 grains it appeared to act as a diuretic, and could be detected for a short time in the urine, in consequence of the color which it assumes on the addition of potash, [2] .

Respiratory Organs.

Most aggravated dyspnoea, [1] . Panting breathing, [8] .

Generalities

Universal swelling, [1] . Exhaustion, [8] .

Fever

[20.]

Heat (especially of the hands), [8] .