Agaricus

With its active principle, Muscarine , presents a very complex physiological study.

Poisonous doses produce violent vomiting and diarrhoea with numerous nervous phenomena ; tonic contractions of smooth muscle fibre everywhere, increased glandular and mucous secretions, persistent anaemia of nerve centres from spasm of arterioles, et cetera .

Its symptomatology offers a large field ; most useful are the chorea-like spasms ; vertigo and general intolerance of the sun ; a heavy weight in occiput ; a very irritable and sensitive spine ; asthenopia with flickerings, twitching of eyes and lids ; (especially valuable for near-sighted people) ; gastro-enteric inflammation with excessive flatulence, inodorous ; irritable bladder ; a host of neuralgic pains everywhere, mostly splinter-like, burning and shooting. Particularly valuable in burning of the skin as from a frost-bite, especially on the ears and feet.

Chorea-like twitchings of various fibrillae and even groups of muscles.

Tremblings, external and internal.

Flesh feels bruised, or as if frost-bitten, sensitive to touch, and to cold air.

General aggravation from walking in the open air, ameliorated when warm in bed.

Pains in the limbs may disappear on motion, and return during rest.

Symptoms often appear cross-wise, as in right arm and left leg, etc.

Shooting, splinter-like pains everywhere.

Delirium ; attempts to escape.

Incoherent talking.

Aversion to mental work.

Confusion and vertigo, aggravated by heat of sun.

Drawing in bones of forehead, to the root of the nose.

Shooting pains, mostly in the sides of the head or in small spots.

Feeling of icy coldness on the head.

Twitching of lids and eye-balls.

Margins of lids red, agglutinating.

Vision dim on attempting to use the eyes.

Flickering.

Type wavers with itching and burning.

External ear burns and itches, as if it had been frozen.

Twitchings of the auricular muscles.

Numerous ringing and other noises within the ear.

Clear water runs from the nose, without inflammatory symptoms.

Pale.

Twitching of the muscles.

Pains lancinating, tearing in the cheek.

Lips :

Upper lip chapped, smarting ; dry, with burning vesicles.

Lips twitch.

Splinter-like pains through the jaws.

Dryness on salivation.

Taste sweet.

Toothache, neuralgic, aggravated by open air.

Splinter-like pains in the tongue.

Stitches extend through right Eustachian tube to ear.

General dryness.

Contractions.

Feels swollen externally, hands feel tight.

Unnatural hunger, evenings.

Eructations, empty.

Numerous sensations (pain, gnawings, boring, cramp, fullness, etc.), with spasmodic contractions, irritable spine, etc.

Flatulent distention, rumblings, cutting, griping, stitches, tension, etc.

Rectum and Anus :

Burning.

Piles.

Emission of much inodorous gas.

Watery diarrhoea.

Constipation.

Irritable bladder.

Burning on urinating.

Stitches.

Discharge of sticky mucus.

Urine lemon colored.

Not profuse (as a rule).

Sexual desire without erections.

In women, violent pressing-tearing pains in back and abdomen with the menses.

Pruritus pudendi.

Respiratory organs :

Constriction of larynx.

Convulsive paroxysms of cough, sudden, end with repeated sneezing.

Expectoration (rare) of balls of mucus.

Respiration difficult as if chest were full ; deep and sighing ; noisy at night.

Numerous pains, tearing, pinching, tensive, stinging, burning.

Constriction.

Oppression.

Heaviness.

Rawness.

(Compare back.)

Palpitation.

Tumultuous action.

Irregular, intermittent pulse.

Ameliorated by coffee.

Neck and Back :

Stiffness of nape.

Bruised and strained feelings.

Deep stitches, burning, itching along spine and limbs.

Spine sore to the touch and on stooping.

Extreme pain and soreness in lower dorsal regions, becoming a pulsating on motion.

Numerous and severe pains in the spine, boring, stitching, drawing, soreness, etc.

Mostly in lower dorsal region.

These sensations extend to nape and into the limbs.

Aggravated by walking in open air.

Trembling.

Twitching.

Shooting pains, shifting.

Limbs weary and heavy.

(Pains often ameliorated by motion.)

Jaundice.

Redness, stinging, burning as if frost-bitten.

Itching.

White nodular elevations, with intense itching and burning.

General sleepiness, especially after eating.

Chilliness on motion, in the air, or on lifting, the clothes.

Burning heat on different spots (mostly local).

Profuse inodorous sweat, often localized ; chest.

Sweat oily.