Hippomanes

A normally white, usually dark olive green, soft, glutinous, mucous substance, of a urinous odor, which floats in the allantois fluid, or is attached to the allantois membrane of the mare or cow chiefly during the last months of pregnancy.

Triturations were made from the dried substance obtained from Rev. John Helfrich (one of the provers and an associate of the Allentown Academy) who took it from the tongue of a newly born filly.

The provings are by Hering, Helfrich, Floto, Reichhelm, Husman and Neid- hard. See Allen's Encyclopedia, vol. 4, p. 589.

As the remedy has not, thus far, had frequent clinical application, we give but a condensed extract from the provings.

^ Mind. 1 1 Melancholy; a young man sits in the corner and does not want to have anything to do with the world. Restlessness; must move from place to place. ^ Sensorium. Sensation of lightness in head. ^ Inner Head. Pressive pain in temples.

Headache, with giddiness, heat in head, sleepiness, yawn- ing, thirst. Violent headache ; heaviness on vertex ; when walking it feels as if head would fall forward.

HIPPOMANES. 44

Headache > when lying on painful side; < when walk- ing in sun. * Outer Head. The head feels so heavy that it falls forward if he raises himself. The hair becomes nearly dry ; falling off of hair. ^ Sight and Eyes. The light of the candle looks blue. Stitches in eyes (with headache).

Painfuhiess of eyes when moving them, with headache. ^ Smell and Nose. Sensation of coldness, when drawing t' air in. Bleeding of nose in morning. ^ Lower Face. Involuntary twitching of under lip. ^' Taste and Tongue. Bitter taste in mouth.

Tongue coated white, with redness of tip. ^^ Inner Mouth. Increased secretion of saliva, with headache

or sore throat. ^^ Throat. Painfulness of 1. tonsil.

Sensation of plug in throat (1. side). " Appetite, Thirst. Desires, Aversions. Desire for acids,

and aversion to sweet things. ^•^ Hiccough, Belching, Nausea and Vomiting. Nausea,

especially in a draft of air, with headache. ^'' Scrobiculum and Stomach. Hey coldness in stomach.

Sensation of emptiness in stomach (and head). ^^ Stool and Rectum. Soft stool, with vomiting; discharge of prostatic fluid after micturition. Hard stool, in balls. Spasmodic contraction of sphincter ani. ^^ Urinary Organs. Frequent discharge of watery urine.

Urine discharged in a small stream, with straining — it

feels as if a swelling retarded it; prostatitis. Drawing pain from anus through urethra. ^^ Male Sexual Organs. Sexual desire increased. Prostatitis.

Drawing pain in testicles. ^^ Female Sexual Organs. Menstruation too early. ^ Voice and Larynx. Trachea and Bronchia. Larynx

feels raw, as if air were too cold. '^'^ Respiration. Tickling in throat when breathing. ^^ Cough. Cough, barking, during sleep. ^^ Inner Chest and Lungs. Stitches in 1. side of chest. ^^ Upper Limbs. Left arm feels as if paralyzed. I I Violent pain in wrists. ^Chorea. I 1 Paralysis of wrist, every morning in bed. Sensation in wrist as if sprained, especially left. Great weakness of hands and fingers, so that he cannot

hold anything. Formication on r. hand.

45 - HIPPOMANES.

^^ Lower Limbs. Weakness, and as if sprained, in knees.

Weakness and sensation of dryness in foot joints and soles of feet.

Cramps in soles of feet, in evening.

Cold feet. ^* Limbs in General. Heaviness in limbs. ^^ Rest. Position. Motion. Lying: on painful side, head- ache >.

Desire to lie down, with no relief in doing so.

If he raises himself: head feels heavy.

Must move from place to place.

Walking: head feels as if it would fall forward; in sun headache <. ^^ Nerves. I Great weakness of body and mind.

Great weakness and debility, with pale face.

Desire to lie down, with no relief on doing so.

I Chorea. ^^ Time. Morning: bleeding of nose.

Evening: cramps in soles of feet; heat, with dull headache. ^^ Temperature and Weather. Sun : < headache.

Draft of air : nausea.

Chill: > being warmly covered in bed. *" Fever. Chill, beginning in back.

Chill, > being warmly covered in bed.

Heat in evening, with dull headache. ** Attacks, Periodicity. Every morning in bed: paralysis

of wrists. *^ Locality and Direction. Right: formication on hand.

Left: painfulness of tonsil; sensation of plug in throat; stitches in side of chest; arm feels paralyzed. *^ Sensations. As if head would fall forward when walking; as of a plug in throat; as if a swelling retarded urine; as if air was too cold for larynx; left arm feels as if paralyzed ; left wrist as if sprained.

Violent pain : in head ; in wrists.

Stitches: in eyes; in 1. side of chest.

Drawing pain: in testicles; from anus through urethra.

Cramps : in soles of feet.

Dull headache.

Painfulness: of eyes; of 1. tonsil.

Heat: in head.

Heaviness: on vertex; in limbs.

Raw feeling: in larynx.

Sensation of dryness : in foot joints and soles of feet.

Sensation of emptiness: in stomach.

Great weakness: of hands and fingers; of foot joints and soles of feet; of body and mind.

Lightness: in head.

HIPPOMANES— HIPPOZ^NIK 46

Tickling: in throat.

Formication : on r. hand.

Itching : on skin, especially on chest, between shoulders.

Coldness : in nose when drawing air in ; in stomach. ^^ Skin. I I Itching as from flannel on skin, especially on

chest and between shoulders. ^^ Stages of Life, Constitution, i After growing too fast.

^Chorea. *^ Relations. Antidoted by coffee.

Caustic, relieved paralysis of wrist.

HIPPOZiENIN.

Glanderine and Farcine. A Nosode.

Introduced by Drysdale.

The extracts (made by Hering) are from Wilkinson, Spinola, Bollinger (Ziemsen) and Virchow. They are the effects observed on horses and men affected • with this disease.

Gl. = Glanderine. F. = Farcine. Symptoms so marked are suggested for clinical use by Wilkinson.

Clinical Authorities. — Ozcena, Wilkinson, B. J. H., vol. 15, p. 627 ; Mor- gan, Eaue's Eec, 1873, p. 79; Chronic ozcena, Hiller, Organon, vol. 2, p. 381; Diphtheria, Wilkinson, B. J. H., vol. 15, p. 627 ; Bronchitis, Wilkinson, B. J. H., vol. 15, p. 625; Putrid fever, Wilkinson, B. J. H., vol. 15, p. 627 ; Glanchroid influ- enza, Baer, Eaue's Kec, 1873, p. 108 ; Scrofulous swelling of parotid glaml, Nichols, Organon, vol. 3, p. 345.

Cases by Berridge not found.

^ Sensorium. Fainting turns with headache.

^ Inner Head. Inflammation of membranes of brain.

Purulent collections between bones of skull and dura mater.

Scattered abscesses in brain substance.

Tubercles may appear in periosteum of skull, in dura mater, in plexus choroides.

A diffused myelitis malleosa, attributable to infiltration. * Outer Head. Bones of skull and face, most frontal, necrosed.

Hair loses its glisten. Gl. ^ Sight and Eyes. Eyes full of tears or slime.

Pupils dilated, with collapse.

Papules on choroid coat of eye. ^ Hearing and Ears. Tinkling sounds in ears.

Hoarse and deaf, before fatal termination.

47 HIPPOZ^NIN.

Inflammation of parotid gland. "^ Smell and Nose. Swelling and redness of nose and adja- cent parts, with severe pain.

Difl'used redness of nose spreading over forehead and face.

Upper portion of nose specially sensitive to touch, exhibit- ing a diffuse, erysipelatous swelling.

Erysipelas especially upon nose and face.

Gangrenous erysipelas of external integuments of nose, discharge of pus and viscid mucus down one or both nostrils. Gl.

Discharge of a thin, viscid, light colored mucus from nose.

Offensive muco-purulent discharge from nose.

Nasal secretions have a foul appearance, before fatal ter- mination.

Nasal discharge often from one side only.

Discharge from nose becomes later of a thicker consistency, more purulent, often of a brownish-yellow color, san- guineous and offensive.

I Catarrh: nose inflamed with thick and tinged defluxion; tonsils swollen, fauces gorged. Gl.

■ Obstinate catarrh. Gl. Ozsena; ulcers inside of nose.

Discharge: often one-sided, albuminous, tough, viscous, discolored, gray, greenish, even bloody and offensive; acrid, corroding.

One nostril appears smaller from swelling.

Little yellow pustules size of a hemp seed on nose.

Ulcers deep, lard-like fundus; edges pectinated, elevated, viscous secretion, no scurfs, most in groups at first size of a lentil, running together.

Ulcerations progress from below upwards.

I Chronic ozsena.

Small papules of yellowish color are seated upon mucous membrane of nose.

Distinct tubercles situated mostly upon alee nasi.

Pustules and ulcers on mucous membrane of nose, ter- minating in erosion of perichondrium and perforation of septum and vomer.

Nostrils covered with foul, crustaceous deposits.

Nostrils covered with a viscous phlegm. Gl.

■ Nose and mouth ulcerated. ^Catarrh. Gl. I I Malignant ozsena.

Gangrene of swollen root of nose.

Cartilages of nose become exposed and necrosed, septum,

vomer and palatebone disorganized. Cartilages of the nose are destroyed. Gl. i Caries of nasal bones. Catarrhal, inflammatory, ulcerative processes in other mu-

HIPPOZ^NIN. 48

cous membranes than of nose, conjunctiva of eyes, rau- cous membranes of mouth, gums, fauces and entire res- piratory canal.

iCliecks the liability to catarrhal affection. Gl. ^ Lower Face. Maxillary gland swollen, like a distinct ball or sausage, firmly attached to the maxilla, uneven, rug- ged, tuberculated; mostly painless, burning only at times.

Submaxillary and sublingual glands swollen and painful at times; abscesses are formed which open externally. ^^ Teeth and Gums. Gums show a tendency to bleed.

Gums covered with a black, sooty deposit. " Taste and Tongue. Act of speaking difficult.

Tongue dry, thickly covered with a black, sooty deposit. ^^ Inner Mouth. Dryness of mucous membranes of mouth and pharynx, before fatal termination.

Stomatitis.

Ulcers appear in mouth.

i Buccal passages filled with tenacious lymph and mucus. (^Scarlatina. Gl.

Croupous exudation upon mucous membrane of mouth and throat.

■Apparently suffocating from diphtheritis in mouth and nose, agonized with buccal ulcerations. ^Diphtheria. Gl.

\ Odor of breath putrid. ^Scarlatina. Gl.

■ Scrofulous swelling of 1. parotid gland in a child. 13 Throat. Ulcerations upon velum of palate.

I Swollen tonsils closing posterior channels. ^Scarlatina. Increased difficulty in swallowing, before fatal termination. Mucous membrane of fauces ulcerated, yellow, like bacon. Upon mucous membrane of pharynx ecchymoses, redness,

swelling, eruptions and foul ulcers. Inflamed condition of pharynx makes swallowing difficult.

■ Patient apparently suffocating from diphtheritis in

mouth and nose; buccal ulceration present. " Appetite, Thirst. Desires, Aversions. Appetite failing;

loss of appetite. Gl. Thirst excessive, especially with diarrhoea. ^^ Scrobiculum and Stomach. Gastrointestinal catarrh ;

loss of appetite, indigestion, constipation, in later stage

diarrhoea. Large ecchymoses on mucous lining of stomach. Papula shaped formations in substance of lining mem- brane of stomach. ^^ Hypochondria. Liver greatly enlarged, often showing

signs of fatty degeneration. Hepatitis with gangrenous and ulcerative inflammation

of gall ducts. Enlargement of spleen.

49 HIPPOZiENIN.

Spleen enlarged, filled with blood ; softened and liquified, of a grayish-red or dark color; wedge-shaped abscesses in spleen. ^^ Abdomen. Inguinal glands swollen.

^'^ Stool and Rectum. Colliquative diarrhoea with a general cachexia and exhaustion precede the fatal termination.

Involuntary evacuations with collapse.

Constipation. ^^ Urinary Organs. Tubercles and abscesses in kidneys.

Suppuration in one kidney. Gl.

Albumen in urine, also leucine and tyrosine. ^^ Male Sexual Organs. Tubercles and abscesses : of glans penis; of testicles ; in kidneys.

Sarcocele malleosa.

Swelling and inflammation of testicles. Gl.

:' Syphilis. Female Sexual Organs. Slimy discharge from vagina.

i Uterine phlebitis. F, ^ Pregnancy. Parturition. Lactation. Abortion. ^^ Voice and Larynx Trachea and Bronchia. Papules and ulcerations m frontal sniuses, pharynx, larynx and trachea.

Extensive lesions in larynx, subsequent oedema of glottis.

Hoarseness from the altered condition of larynx.

■ Neglected cases of bronchitis.

1 1 Bronchitis: in the worst forms; especially in elderly per- sons; where suffocation from excessive secretion is im- mment. Gl. ^Respiration Noisy breathing; loud snoring respiration before fatal termination ; breath fetid.

Respiration short and irregular, with collapse.

Slight difficulty in breathing.

II Cough and obstructed respiration, resulting from cic- atricial contraction of mucous membrane of nose and larynx; had lasted eleven years; patient jDresented picture of decided cachexia.

Respiration at first partially impeded, later absolute dysp- noea.

Actual dyspnoea from affection of larynx or lungs.

1 1 Suffocation from excessive secretions. ^Bronchitis. Gl.

• Bronchial asthma. Gl. ^ Cough. Irritative cough.

Slight cough and hoarseness, sputa often bloody.

I Cough comenced at Christmas and lasted till June. Gl.

I Whooping cough. Gl.

Patients cough severely and expectorate profusely, sputa usually bearing a strong resemblance to the discharge from the nostrils.

VOL. VI. — 4.

HIPPOZ^NIK 50

^ Inner Chest and Lungs, Extensive rhonchi are heard over walls of chest.

Large sections of lungs in a state of gray hepatization and purulent infiltration, while other portions are in a state of collateral hypersemia.

Pneumonia with rysty sputa. Gl.

Pneumonia malleosa; nodules larger, forming isolated hepatizations and abscesses.

One or two infarctions in lungs, size of a bean developed in one lobe, distinctly circumscribed dark red color, in and around wdiich lie small abscesses.

Nodules in lung size of a pea, of a gray whitish appear- ance and a firm, lardaceous consistence.

Tubercles in lungs.

Tubercles, size of millet seed to a pea, of a firm texture and of a gray, yellowish or reddish color.

Tubercles in lungs are never missed in glanders, rarely in farcy.

Tubercles in lungs, nodules and specific inflammatory processes.

Small tubercles upon pleura; subpleural ecchymoses.

Pulmonary abscesses with pleuritis.

: Given in phthisis, it diminishes expectoration, abates constantly recurring aggravations of inflammation, and checks liability to catarrhal aff'ections.

Suppuration of lungs. Gl.

I Lung diseases of cattle. F. ^ Heart, Pulse and Circulation. Pulse very frequent and

small in volume, 110 to 120; in some cases retarded. ^^ Upper Limbs. With sore finger, swelling of arm, phleg- monous and erysipelatous with pustules and ulcers. ^ Lower Limbs. • Hip disease.

': Psoas and lumbar abscesses. F.

i Old bad legs (ulcers). Gl.

Suppuration in each knee-joint; a large quantity of pus in bursa of knee-joint. Gl.

• Anasarca of lower limbs. F. ^' Limbs in General. Obscure pain in limbs, most in mus- cles and joints. ^'^ Nerves. Weakness, fatigue, general discomfort; they give up their business (not in carbuncle).

Malaise, fatigue, prostration, accompanied by headache and chills.

General prostration with considerable emaciation. ^ Sleep. Insomnia and great restlessness.

Nocturnal delirium. *'' Fever, Frequent chilliness. Gl.

Chills and fever in cases of abscesses or ulcers.

HIPPOZ^NIN.

Skin becomes cool with collapse.

Symptoms like the early stage of typhoid fever.

Fever exacerbations irregular or of a regular intermittent character.

Febrile disturbances constantly increasing.

As the pains become more severe, regular fever turns often supervene or a continued fever prevails.

Fever when a series of abscesses follow in rapid succession.

Temperature reaches 104° F. and over.

Fever raging without intermission, even in morning, tem- perature 106° F.

Fever increases, pulse grows weaker, delirium sets in, stupor.

I Putrid fever. Gl. Plague. Gl.

May be tried in scarlatina, where odor of breath is putrid,

buccal passages filled with tenacious lymph and mucus,

tonsils greatly swollen,

" Attacks, Periodicity. At times: burning in maxillary

glands; pain in submaxillary and sublingual glands.

Cough commenced at Christmas and lasted till June.

Lasted eleven years: cough and obstructed respiration. ^^ Locality and Direction. Left: scrofulous swelling of pa- rotid gland. *^ Sensations. Pain is excessive in acute articular rheumatism.

Attacks of muscular cramps before fatal termination.

Violent pains: in joints and muscles.

Severe pain: in nose and adjacent parts.

Obscure pain: in limbs; in muscles and joints.

Painfulness: of tumors and abscesses; of submaxillary and sublingual glands.

Painful swelling: of joints.

Burning: in maxillary glands.

Dryness: of mucous membranes of mouth and pharynx. ** Tissues. Greatly debilitated and emaciated, presenting a very similar appearance to that seen in chronic tuber- culosis with hectic fever.

Extrusion of contents overbalances supply of nutrition.

Numerous ecchymoses in internal organs.

Inflammation of lymphatic vessels and swelling of glands.

': Lymphatic swellings and inflaftimation.

On legs, head, sides, chest, near genitals, in long strings, hard swellings from size of a pea to that of a hazel or walnut ; after enlarging they break open and discharge a viscous, yellow brownish ichor.

• Phlegmasia dolens.

Entire process presents a strong resemblance to certain forms of pyaemia.

HIPPOZ^NIN. 52

I Pyaemia and inflammation of veins and lymphatics, par- ticularly when pus is formed.

The mucous membranes (first of all that of the nose) manifest symptoms of inflammatory and ulcerative disease.

Inflammatory aff'ection of mucous membrane of mouth followed by swelling of tongue, salivation, ulcers upon gums and throat, finally angina.

Purulent inflammation in serous membranes, especially lining membrane of joints, particularly of knee, hips and hand.

Painful swelling of joints.

Pain in joints and muscles become violent.

i Enlarged joints.

Periarticular nonfluctuating tumefactions.

Large projecting tumors and abscesses becoming ex- tremely painful and hard, then gradually changing to a doughy consistence; fluctuating; after opening, appear as extensive ulcers with irregular edges covered with a white deposit.

The specific nodules mostly in biceps, flexors of forearm, rectus, pectoralis and at point of insertion of deltoid.

Beneath larger blebs well defined sloughs of a dull gray color.

I I Putrescence, destructive, quasi malignant ulcerative tendency to decomposition of tissues. Gl.

1 Malignant erysipelas, particularly if attended with large formation of pus, destruction of parts. Gl.

: Dropsy.

All the attacked parts swell, get cedematous.

Beneath oedema are small nodules, varying in size and filled with reddish pus.

Skin cracks in bend of joints, a brownish fluid oozes out, and gets ulcerous.

Purulent infiltrations of skin and cellular tissues, especially upon forehead and eyelids and in vicinity of joints.

Abscesses in various parts of body in course of absorbents.

I Carbuncle.

I Plague. Cancer. Elephantiasis.

Obstinate syphilitic sores, with great fetor. Scrofula.

I Abates recurring aggravation of inflammation.

i Murrain of cattle. *^ Touch. Passive Motion. Injuries. Touch: upper por- tion of nose sensitive.

53 HIPPOZ^NIN.

i Putrid bedsores. Gl. ^® Skin. Erythema, erysipelatous or phlegmonous processes, abscesses, pustules and ulcers are spread so extensively over surface of body that hardly any part remains free.

■ Malignant erysipelas, particularly if attended by large

formations of pus, and destruction of parts. Gl.

: Scarlatina. Gl.

Sensation of pain on part of inoculation followed by a red- ness and inflammation, fever, finally swollen, inflamed lymphatic vessels.

On different parts of skin red spots, changing into pus- tules like those of small-pox, less often into pemphigus blebs.

Pustules of size of pea often arise in large numbers, burst- ing by discharging a thick, mucous, sanguineous pus, often emitting an offensive odor.

Surrounding subfascial abscesses the numerous layers are pale, discolored and readily torn.

Large abscesses upon different regions of the body, with inflamed lymphatic vessels and glands.

New abscesses are constantly forming in vicinity of the ulcers, especially about joints.

Contents of abscesses often tinged with blood, have a more viscous consistence, while connective tissue or muscular substance is softened. Malignant pustule. Gl. Carbuncle. GL

Boils and ulcers.

i Confluent small-pox. Gl.

i Malignant external ulcerations; putrid bedsores; obsti- nate syphilitic sores attended with great fetor.

Ulcers often penetrate so deep as to lay bare the tendons and bone.

Ulcers deep, lard-like fundus, elevated, pectinated edges, slow healing, leaving a star-shaped white scar.

: Putrescence, destructive or quasi malignant ulceration, and tendency to decomposition of tissues.

■ Malignant external ulcerations. Gl. Ulcers have no disposition to heal, livid appearance. Ulcers assume a corroded, chancroid character and a dirty

white hue. Ulcers enlarge, edges and base acquire an unhealthy

aspect, pus offensive. Sinuous and fistulous ulcers, secreting an ofiensive, watery

pus, showing no tendency to throw out granulations. Pustules appear gradually on every part of body. Pustules contain caseous purulent contents.

HIPrOZiENIN— HYDRASTIS CANADENSIS. 54

I Malignant, phagedenic skin diseases. Gl.

\ Pustular ringworm. Gl.

i Lupus cxedons.

Circumscribed or difluscd lesions on skin.

Fluctuating tumors in muscular tissue.

Frequently upon the limbs nodular tumors discharging,

on being opened, thick, purulent masses mixed with

blood and serum. Icterus appears before fatal termination. Here and there healing by forming cicatricial tissue.