Mancinella

Hippomane Mancinella. Euphorbiaceae.

A poisonous tree, a native of West Indies, bearing a poisonous fruit, some- what resembling apples. The tincture is prepared from fresh leaves, bark and fruit.

Introduced and proved by Bute. See Hering's compilation, Allg. Horn. Zeit., 1850. Also proved by Mure and Ackermann. Toxicological reports are numerous.

Clinical Authokities. — Affection of throat, Bute, MSS.; Post-diphtheritic affection, Bute, Raue's Rec, 1870, p. 152; Affection of stomach, Bute, MSS.; Pain in I. hypochondrium, Bute, MSS. ; Rumbling in abdomen, Bute, MSS. ; Colic, Bute, MSS. ; Cholera infantum, Howard, MSS. ; Asthma, Howard, MSS. ; Nervous affection, Bute, Hom. Clin., vol. 1, p. 283; vol. 4, p. 19 ; Typhoid fever, Bute, MSS.

^ Mind. I Sudden vanishiDg of thought, forgets from one moment to next what she wishes to do.

■ Everything becomes irksome.

■ Fear of getting crazy ; of evil spirits ; of being taken by

the devil.

■ Averse to work and answering questions.

I I Melancholy, homesickness; about midnight attacks of fear and trembling; afraid of evil spirits, of being taken hold of by the devil; sleeplessness; pressing in cardiac region, hard beats of heart, followed by faintishness,with darkening before eyes; tetters. /^Mental derangement.

Bashful and taciturn; has a timid look.

Aggravation from anger and after eating. ^ Sensorium. Vertigo: stupefying; with loss of conscious- ness; in morning on rising from bed.

■ Sensation of lightness in head while walking about room. ^ Inner Head. Stitches: in temples; in head, with sleepless- ness ; over 1. eye.

Headache: with impatience; caused by candlelight. Pulsating pains in head and neck, preventing one from

writing. Whole head feels sore, as if bruised or as if it had been

exposed to sun. Heaviness in head.

■ Headache, < from warmth of stove.

* Outer Head. Itching of scalp ; hair falls out after severe

acute diseases. ^ Sight and Eyes. Blue circles around eyes.

MANCINELLA. 264

Sensation of heaviness and dryness of eyes and lids. Burning: in eyes, headache from candlelight; of eyelids, only when closing them. ® Hearing and Ears. Ears feel as if closed.

Redness and heat of ears. ^ Smell and Nose. Pressure at root of nose.

Dryness of nose. * Upper Face. Face: swollen; pale; pale, yellow, bloated. Heat rising to face, and soon thereafter painful itching, stitching and burning, continuing all day, next morn- ing face swollen; towards noon vesicles, size of small pinhead and filled with a yellow fluid, next day des- quamation. ^ Lower Face. Lips pale ; pricking pains in lips. Lower lip hangs down.

Large number of small vesicles on chin, which desquamate. " Taste and Tongue. iVery bitter taste in mouth.

I Tongue coated white, except on several sharply defined

clean spots. Burning on tongue; dry. I Tongue coated white as in aphthae.

■ Taste: bloody; < after sleeping.

^^ Inner Mouth, l l Unendurable burning and prickling in mouth, not > by cold water. I I Whole mouth and tongue covered with small vesicles.

■ Increased flow of saliva; yellow saliva; fetid. Burning at soft palate and roof of mouth. Dryness of mouth.

■ Ofifensive breath, perceptible to herself. Blister, size of hazelnut, on palate. Inflammation in mouth ; bleeds.

13 Throat. ■ Great elongation of uvula.

Heat in pharynx and down oesophagus, without thirst.

■ Great dryness of throat; on waking.

■ Choking sensation rises in throat when speaking. Stitches in throat.

Sensation of constriction in throat, ascending from stom- ach, caused by accumulation of air, with palpitation of heart and great sensation of weakness, impeding speech.

■ Thirst for cold water, with inability to swallow on account

of a choking which rises up from stomach. ■Angina following scarlet fever, or during epidemic of latter. I I Periodical thrusts (as if electric) in upper part of throat,

waking from sleep. ■Yellowish white ulcers, with violent burning pain.

■ Great swelling and suppuration of tonsils, with danger of

suffocation; whistling breathing.

■ Sore throat during scarlet fever.

265 MANCINELLA.

■ White yellowish burning ulcers on tonsils and in throat.

■ Diphtheria on 1. side; ever since, pains all over her body,

mostly in chest, with a dry cough. I I Menses irregular, profuse; heat in head, with vertigo; >

w^hen at rest; edges of eyelids burn when closing eyes.

^Post-diphtheritic affection. ^* Appetite, Thirst. Desires, Aversions, i Thirst for cold

water, but is prevented from drinking by choking sen- sation rising from stomach; with burning heat. Aversion to meat and bread.

Longing for water and aversion to wine and alcoholic drinks. '^ Eating and Drinking. Can take none but liquid food on

account of soreness of mouth. I Drinking water, bloatedness and painfulness of region of

stomach <. I After drinking w^ater: colic; pain in abdomen. ^® Hiccough, Belching, Nausea and Vomiting, i Ineffectual

desire to eructate or gag with excessive nausea. II Continual choking sensation, rising from stomach like

from pressure of wind, with weakness and palpitation

of heart. I I Repeated green vomit. iSour. greasy vomit, with aversion to water; on vomit

floats a white mass like coagulated fat. I I Vomiting of food, followed by severe colic and profuse

diarrhoea. I I Vomiting relieves headache. ^^ Scrobiculum and Stomach. Burning: in stomach and

throat, with nausea; in pit of stomach.

■ Pit of stomach swollen and sensitive to pressure.

■ Distension and pain in region of stomach.

■ Bloatedness and painfulness of region of stomach. ^Ner-

vous fever. ■Sensation as of flames rising from stomach. ■Sensation as if stomach drew together in a lump and

then suddenly opened. ^^ Hypochondria. • ' Rumbling in 1. side when bending to right. I I Sudden sticking in 1. hypochondrium.

■ Pain in 1. hypochondrium in a spot as large as a half

dollar, compelling her to press there with hand ; rum- bling in 1. side M-hen lying on r. side, also with every respiration ; no rumbling when lying on 1. side. ^^ Abdomen. ■Wandering pains in abdomen.

■ Pains in abdomen through bowels, after drinking w^ater,

■ Loud rumbling in abdomen.

■ Rumbling in abdomen renewed by every motion and

when taking a deep inspiration, with headache which is much < near warm stove.

MANCINELLA. 266

I Colic : after drinking water; with diarrhoea (at midnight);

with fainting, constipation, alternating with diarrhoea. I I Distended abdomen.

I I Sensation of soreness, as if bruised, of abdominal walls. I I Eruptions of rash on abdomen. ^ Stool and Rectum, l l Fulness in rectum, with a hollow

feeling in stomach. I I Profuse diarrhoea, with colic and vertigo. I I Many bloody stools, with colic, inclination to sleep and

I I Greenish stools, without blood.

I Diarrhoea: with burning in abdomen and anus; in alter- nation with constipation ; with cutting in abdomen ;

from hemorrhoidal tumors. I Frequent thin, watery discharges; vomiting; emaciation ;

great prostration ; loss of appetite ; aversion to food.

^Cholera infantum. I Constipation. ^^ Urinary Orgfans. ' ' Tired feeling in region of kidneys, with

inclination to rub parts, and with frequent stretching

I Urine : brown ; whitish, clouded on standing. ^^ Male Sexual Organs, i l Increased sexual desire.

Itching on scrotum. ^^ Female Sexual Organs, i i Pale menstrual flow ; colic.

Before menstruation : congestion of head. ^ Voice and Larynx. Trachea and Bronchia. ■ Nasal tone

■ During breathing: rattling in 1. chest; loud rumbling

in abdomen ; severe pain in middle of sternum, < from pressure.

■ Asthma, chronic.

^^ Cough. ■ Frequent hawking, with nausea.

267 MANCINELLA.

. I Violent cough and painful stitches in trachea from slightest exertion. I Cough : < at night ; after drinking.

■ Expectoration reheves oppression of chest.

■ Rattling in 1. chest.

Suffocative attacks, with pulsation in chest, while cough- ing, or as soon as he begins to talk.

Stitches in middle of sternum.

I Pain in centre of sternum, < from pressure and from breathing. ^^ Heart, Pulse and Circulation. Stitches in heart as from needles.

■ Palpitation of heart: in evening, as from eating; weakness.

■ Pulse: weak and somewhat accelerated; 80.

^ Outer Chest. ■Stitches in middle of sternum; < from

■ Painful stiffness of small of back.

■ Tired sensation in region of kidneys, desire to rub part;

much stretching.

■ Painful stiffness of small of back and of finger joints

■ Hands as if too thick, "asleep," heavy and clumsy.

■ Hands icy cold.

■ Pain and stiffness of finger joints. Blue finger nails.

^ Lower Limbs. ■ Quivering and jerking in legs in attacks. Trembling of legs.

■ Burning in soles and dr}' feeling.

■ Desquamation of soles at end of fever.

■ Large vesicles, especially on soles.

MANCINELLA. 268

Must lie down: pulse irregular, limbs cold, great anxiety; severe headache.

Sitting: tingling in feet.

Frequent stretching back: of body, tired feeling of region of kidneys.

Every motion : renews rumbling in abdomen.

Slightest exertion : violent cough and painful stitches in trachea.

Could scarcely move neck : stiffness.

Walking : about room ; lightness in head. ^ Nerves. Lassitude and indescribable uncomfortable feeling in limbs.

I Much stretching, with tired feeling over region of kidneys.

Must lie down, pulse irregular, limbs cold, great anxiety.

• Prostration and trembling in limbs.

■ Fainting with intestinal colic.

Convulsions.

I About midnight, attacks of fear and trembling, followed by feverish heat; afraid of evil spirits; of being taken hold of by the devil ; sleeplessness ; only somewhat re- lieved towards morning; fears she is getting crazy; anxious expression in face ; dark brownish circles around eyes; throbbing in pit of stomach; pressure in region of heart, hard beats of heart followed by fainty feelings, with darkening before eyes; pulse slow and soft; fre- quent headache ; desire for saltish food ; smell of onions before nose; menses one week too early, with pains in chest; feet puffed up every morning; on chin, old, dark tetter with red pimples.

I After typhoid fever: frequent shooting pain like a streak down r. arm ; constant soreness, extending from region of r. kidney into back and around to liver; sometimes extending down to legs like rheumatism; head feels heavy, often as if it had been squeezed fiat, sometimes as if hollow; when lying, her head feels as if lying on something hard; pain over r. eye; feeling of weakness extending from forehead down into nose; appetite changeable, sometimes hungry without appetite; after eating, feeling as if hard pieces were lying in stomach, with some nausea ; eating very little makes her imme- diately very full ; constant desire for sour dishes, parti- cularly for indigestible things (puddings, half baked bread, and the like); continual feeling of fulness in stomach, as if food would come up again; feeling in pit of stomach as of something alive; raw sensation extend- ing down throat; speech often weak; palpitation on turning in bed; contracting sensation in different parts, mostly of abdomen ; pain in region of bladder while

269 MANCINELLA.

urinating; menses a few days too late, sometimes very dark, sometimes bright, again greenish and offensive, with tearing pain in lower part of abdomen; much rest- lessness; crawling and digging on different parts of .body; sometimes feels as light as though she could float or hover in the air; mind much depressed, weeps a great deal, particularly when alone; full of fear of getting crazy ; > during evening. ^Nervous aff'ection. ^ Sleep. I Great sleepiness; ineffectual desire to yawn.

I Wakes as from electric shocks on neck (above larynx).

I When awaking hands ''asleep " and heavy, and feel as if too thick.

After sleep: bitter mouth; dryness in throat; could scarcely move neck. ^ Time. Morning: on rising, vertigo; sudden desire to go to stool ; attacks of fear >.

Towards noon: vesicles, size of small pinhead, on face, next day desquamation.

All day : painful itching, stitching, burning in face.

Afternoon : more than twenty evacuations.

Evening: palpitation of heart; nervous affection >.

Night: cough <.

Midnight : attacks of fear, trembling, diarrhoea and colic. ^^ Temperature and Weather. Warmth of stove : headache <.

Inclination to uncover himself: burning heat.

Cold water : does not > prickling and burning in mouth.

Amelioration from heat and when lying down. *° Fever. ■ Chill; icy cold hands and feet.

■ Flushes of heat, with sensation as if flames rose out of re-

gion of stomach, on account of which threw off covering.

■ Burning heat, with inclination to cover himself in bed;

Coldness of hands and feet. Fever heat with tingling in skin and desire to uncover

one's self, with loss of consciousness, painful deglutition,

restlessness, profuse micturition.

■ Typhoid fever with tympanitis and sensitiveness of ab-

MANCINELLA. 270

side when bending to r. ; sudden sticking in hypo- chondrium ; pain in hypochondrium ; lying on r, side, rumbling in other; lying .on 1. side no rumbling; rat- tling in chest ; stitches in shoulder blade and breast.

From without inward : stitches under heel. *^ Sensations. As if head was bruised, or as if it had been exposed to sun ; ears feel as if closed ; thrusts, as if elec- tric, in upper part of throat ; as of flames rising from stomach ; as if stomach drew together in a lump and then suddenly opened ; abdominal walls as if bruised ; as if fire was in intestines ; region of kidneys as if bruised ; stitches in heart as from needles ; hands feel as if asleep and numb ; hands as if too thick ; head as if it had been squeezed flat ; head as if hollow ; head as if lying on something hard ; after eating as if hard pieces were lying in stomach ; as if food would come up again ; in pit of stomach as of something alive.

Pain : in head ; all over her body, < in chest ; in abdomen; in region of stomach ; in 1. hypochondrium in a spot as large as a half dollar ; in intestines ; in centre of sternum ; in chest ; over r. eye ; in region of bladder.

Severe pain : in middle of sternum.

Tearing pain : in lower part of abdomen.

Shooting pain : down r. arm.

Violent burning pain: in throat.

Cutting : in abdomen ; in larynx.

Stitches : in temples ; in head ; over 1. eye ; in throat ; in bladder; painful in trachea; in 1. shoulder blade and 1. breast ; under heel.

Needlelike stitches : in lower extremities.

Sticking : in various parts of body.

Sudden sticking : in 1. hypochondrium.

Pulsating pain : in head and neck.

Pricking pains : in lips.

Contractions: in opposite directions.

Short, sharp stitches : here and there.

Wandering pains : in abdomen.

Severe colic : in abdomen.

Cramps : in legs and feet.

Aching : in back.

Unendurable burning and prickling; in mouth.

Painful itching, stitching and burning : in face.

Burning : in eyes ; of eyelids ; on tongue ; at soft palate and roof of mouth ; in ulcers on tonsils and in throat ; in stomach and throat ; in pit of stomach ; in abdomen and anus ; in urethra ; in soles.

Soreness: of throat; of mouth; of abdominal walls; in region of kidneys; from region of kidney into back and around to liver, sometimes down to legs.

271 MANCINELLA.

Heat : of ears ; rising to face ; in pharynx and down oesoph- agus; in head.

Sore feeling : in whole head.

Painfulness : of region of stomach.

Raw sensation : extending down throat.

Crawling and digging: on different parts of body.

Painful stiffness: of neck; of small of back; of finger joints.

Pressure: at root of nose ; in region of heart.

Pressing: in cardiac region.

Heaviness: in head; of eyes and lids; of arms.

Fulness: in rectum; in stomach.

Oppression: of chest.

Tension : in larynx.

Contracting sensation : in different parts, mostly abdomen.

Constriction: in throat, ascending from stomach; of chest.

Choking sensation : rises in throat.

Indescribable, uncomfortable feeling : in limbs.

Light feeling as though she could float or hover in air.

Lightness : in head.

Hollow feeling : in stomach.

Tired feeling : in region of kidne3^s.

Weakness : of heart ; in region of kidneys ; from forehead into nose.

Dryness : of eyes and lids ; of nose ; of tongue ; of mouth ; of throat ; of soles.

Tingling : in feet.

Trembling: of hands; of legs; of limbs.

Pulsation : in anus ; in chest.

Throbbing : in pit of stomach.

Quivering and jerking : in legs.

Inclination to rub region of kidneys : tired feeling. *' Skin. Pvedness of skin (hands).

iSequelse of scarlet fever.

■Small vesicles containing yellow serum desquamate fol- lowing day.

■ Favors rapid healing of wounds.

■ Fungoid growths, particularly if syphilitic.

MANCINELLA— MANGANUM. 272

Young woman, had diphtheria onl. side; post-diphtheritic affections.

Woman, set. 24, unmarried, after typhoid fever; nervous affection.

Mrs. R., set. 31, dark hair, liver spots in face, mild, some- what melancholic temperament, disposed to homesick- ness, mother of six children ; nervous affection.