Hydrophobinum

Hydrophobinum.

Lyssin.

The nosode of rabies.

Trituration of sugar of milk saturated with the saliva of a rabid dog.

Triturations might also be made of Pasteur''s strongest virus.

Clinical (Hydrophobinum)

Bubo.

Clairvoyance.

Convulsions.

Corns, pains in.

Diarrhoea.

Dysentery.

Hair, oiliness of.

Hydrophobia.

Hypersensitiveness.

Landry''s paralysis.

Leucorrhoea.

Lyssophobia.

Mania.

Nervousness.

Neuralgia.

Oesophagus, stricture of.

Paralysis.

Pregnancy, convulsions of ; toothache of.

Respiratory paralysis.

Salivation.

Satyriasis.

Sciatica.

Sunstroke.

Tetanus.

Ulcers.

Uterus, prolapse of.

Vaginismus.

Wounds, too rapid healing of.

Characteristics (Hydrophobinum)

Hering was the first (1833) to prove, and to suggest the employment of this nosode in medicine ; and of late years it has become notorious through the experiments of Pasteur. Pasteur''s method of administration is very different from that employed by homoeopaths, but he is working on homoeopathic lines in seeking to neutralise a virus in the system by introducing a modification of the same virus.

The "cure" is, however, extremely uncertain, as the degree of susceptibility to the poison is unknown in any case, and many hundreds of the patients subjected to the inoculations have died of the disease. Pasteur''s first method was admitted to be too strong, and was soon modified ; a number of patients having died from the inoculations. One of these cases I investigated, and the symptoms were sufficiently striking to deserve recording.

It would be well to have as an alternative preparation, Hydrophobinum Pasteurianum, obtained from Pasteur''s vaccin, to meet conditions similar to these. The pathogenesis of Hydrob. is made up partly of symptoms observed in rabid animals and human patients, but chiefly of symptoms developed in the provings. The remedy has been pretty extensively used in practice, not only in cases of hydrophobia, but in many disorders in which the keynote symptoms have been present.

Many symptoms are < by stooping ; by motion generally.

Sensitive to any changed position.

Bending head backward > pain in neck.

Throws head back when sneezing.

Heat of sun <, it is unbearable.

Hot steam directed to bitten place > burning pain in it. > Turkish bath.

Damp warm air oppressed him.

Sensitive to least breath of air ; air of agreeable temperature feels cold.

Slightest draught < Cold air > headache.

< From slightest touch ; from riding in carriage.

Relations (Hydrophobinum)

The remedies most closely related to Hydrob. are those which have cured cases of the disease — Bell. , Stram. , Hyo. , Fagus, Agave, Laches. , Canth. , and the animal poisons generally.

Lachesis is a very close ally (< from sun ; bluish discoloration of wounds ; irritability ; < warm, damp air ; from touch and pressure ; though the late evolution of the symptoms of Hdphb. contrasts with the lightning-like rapidity of snake-venom effects).

Compare also : in ascending paralysis, Gels. , Con. ; in respiratory paralysis, Solania, Bell. , Dulc. ; in sexual excitement, Canth. , Pic. ac. , Graph. ; in intolerance of sun, Gels. , Glon. , Nat. , Lach. , Apis ; in effects of carriage-riding, Coccul. ; desire to urinate on seeing running water, Canth. , Sul. ; convulsions from dazzling light, Stram. ; consciousness of womb, Helon. ; viscid saliva, Epipheg. , Hydras. ; hurried speech, Hyo. ; in coldness, Helod.

Is followed well by : Nat. m.

Causation (Hydrophobinum)

Dog-bites.

Symptoms

Mind (Hydrophobinum)

(Mania spermatica in stallions. ).

A strong and uncontrollable impulse to do certain acts ; to spring at and bite any moving object that came within reach ; dog (Rage).

Attacks of nervous headache become awful and insupportable if he hears water run out of a hydrant.

Break out of their stables furiously and run or jump over ditches and fences (sheep).

Copper, if in his room, makes him restless and full of pains (Rage).

Does not hear or see persons around him (Rage).

During convulsions, mental illusions and hallucinations ; in intervals of consciousness mental faculties are retained (Rage).

During the tranquil intervals, responded correctly to questions put to him, recognised those around him, and with a presentiment of impending death, begged them to pray for him and not leave him alone (Rage).

Exhilarated, felt as if he had received joyful intelligence.

Fancies he is blown at by several persons, some of whom are not present (Rage).

He could hear what was spoken in next room, and counted coppers in a room below him (Rage).

He says he can see hands on dial plate of church clock (Rage).

Hypersensitiveness of all the senses.

Ill-humour.

Imagine that they are abused, and energetically defend themselves against attacks and insults, which in reality are products of their own fancy (Rage).

Inclination to be rude and abusive, to bite and strike.

Insane ideas enter his head ; for instance, to throw a glass of water, which he is carrying in his hand, into some one''s face, or to stab his flesh with the knife he is holding, and the like.

It seems to her as if two entirely different trains of thought influenced her at the same time.

Lament with great anxiety their inability to relieve thirst which afflicts, and by various contrivances endeavour eagerly to drink (Rage).

Linen dipped in sugar water, put on pit of stomach, gives a sweet taste in mouth (Rage).

Loss of consciousness sometimes at an early stage, but not generally until a short time before death (Rage).

Memory for single words much improved.

Most commonly the mental faculties are in a superior state of excitement, shown by quick perception, amazing acuteness of understanding and rapidity with which they answer questions (Rage).

Not afraid of dogs, but dislikes to see them because their sight renews her fear (Lyssophobia, after bite by non-rabid dog).

On a watch held to scrobiculum he sees the hour and minute hands (Rage).

Sometimes he would control inclination to stool by a strong effort of will, but effort caused much nervous irritation.

Strange notions and apprehensions during pregnancy.

The mere sight of a drinking vessel containing water is intolerable ; they turn away their faces, shriek out loud, beckon anxiously with hands to have water removed, for voice and breath fail (Rage).

They appreciate the formidable character of the disease and speak frequently with a remarkably quick and sharp articulation of the impending fatal results (Rage).

Thinking of fluids of any kind, even of blood, brings on convulsions.

Thinks he is a dog or a bird, and runs up and down, chirping and twittering, until he falls down fainting (Rage).

Thoughts of something terrible going to happen come into his mind against his will ; feels impelled to do reckless things, such as throwing a child, which he carries in his arms, through the window.

When he hears water poured out, or if he hears it run, or if he sees it, he becomes very irritable, nervous ; it causes desire for stool and other ailments.

Head (Hydrophobinum)

A slow vacillation or wavering of the head, from something being loose in upper part of head.

At noon slight headache, lasting all day.

Beating, throbbing headache ; most severe in right temple and above right eye ; each bone feels shattered and sore ; from temple to temple.

Burning aching from left side of occiput down neck.

Frequent pressure on vertex, as if a cast, which fitted top of head, was pressing it down.

Hair which is usually dry has become very oily.

Headaches from bites of dogs, rabid or not.

In rare cases serous effusion in opaque sub-arachnoid tissue and lateral ventricle, and also increased adherence of membranes of brain to convolutions (Rage).

Irritable headache, touching head makes it ache ; very sensitive scalp.

Maddening outward pressing pain in forehead ; he presses his head against the wall.

Peculiar lightness in head ; lightness after nausea.

Rush of blood to head : while lying down ; from chest upward, with toothache ; during pregnancy ; when rising.

Scalp feels contracted and pinched.

Violent headache and backache.

Violent headache, most in temples and forehead, < during day and from stooping and stirring about.

Eyes (Hydrophobinum)

Clairvoyance.

Extreme ulceration of eye, lids closed and puffed up by pus (in sheep).

Eyes are wild, rolling, staring and livid (Rage).

False vision, dullness of sight, together with dilatation of pupils, sometimes actual blindness.

Pain in small spot over right eyebrow, < writing.

Sensitive to light.

Sight of water-agitation ; renews idea of pain ; causes convulsions (pregnancy).

Swelling of eyelids after bite of dogs (cured in sheep).

Vision much impaired or absent ; lasts twelve hours.

Ears (Hydrophobinum)

Clairaudient.

Conversation in vicinity of patient may throw him into a most violent agitation (Rage).

Hearing water poured out in next room makes him very irritable and nervous.

Nose (Hydrophobinum)

Frequent sneezing, mostly early in morning or late in evening, as if a coryza would begin ; also when looking at something bright, and from every little dust.

Strong odours may start spasms.

The greatest sensibility to smell of tobacco ; tastes snuff while box is one foot distant.

Face (Hydrophobinum)

Both jaws feel stiff ; tingling in cheek-bones.

Face sweat : with sensation of heat ; with flushes.

Facial muscles become variously contorted, countenance changes its aspect frequently.

Gnawing and crawling sensation in (right) zygoma.

Lower jaw stiff and painful ; with inclination to yawn ; with headache ; imagines he cannot open his mouth.

Masseter muscles not affected by spasms.

Spasms with froth before mouth (Rage).

The jawbones feel sore ; aching in lower jaw.

Teeth (Hydrophobinum)

Grinding of teeth.

Toothache and other complaints during pregnancy, with internal ebullition of blood from chest to head ; head feels as if filled with air to bursting.

Mouth (Hydrophobinum)

Difficult, incorrect speech (stricture of throat).

Entire mucous membrane of mouth and pharynx was of an equally distributed pink without any swelling.

Feeling of coldness in mouth, like essence of peppermint.

Frothed at mouth, attempted to spit out with much difficulty (before death).

Pricking sensation under tongue.

Ranula returns periodically, with dryness of mouth, < in afternoon, soreness when chewing ; with haemorrhoids and constipation.

Saliva more viscid, constant spitting, feeling of general malaise.

Severe pain passing from mouth upward through head and down into neck.

Tongue coated with foam (Rage).

Tough, short frothy phlegm in mouth (horse).

When vomiting ceased, frothing at the mouth began and was so excessive as nearly to choke him (Pasteur).

Throat (Hydrophobinum)

Cooling sensation in oesophagus.

Periodical spasm of oesophagus, continual painful inclination to swallow without being able to swallow anything ; constriction is most severe when taking water into mouth, if he tried to swallow it forcibly, he had burning and stinging in the throat, cough and retching which forced fluid from his mouth ; difficult speech.

Slight redness of palate and throat, with spasm of oesophagus and difficult speech.

Sore throat, as after swallowing red pepper.

Sore throat, constant desire to swallow ; much saliva and feeling as if beaten.

Appetite (Hydrophobinum)

Abnormal cravings during pregnancy.

Aversion to fat food and drink ; there remains a long greasy aftertaste, < after mutton.

Excessive desire for salt.

Inability to take solid food, or else it is consumed with greatest difficulty.

Voracious appetite ; swallowed wheat without chewing.

Warm drinks, such as milk, soups and wine, are more easily taken than water.

Stomach (Hydrophobinum)

Gagging when he forcibly attempts to swallow water, forces it out of his mouth.

Great oppression in stomach, has to open her clothes.

Nausea : with giddiness, headache and pale face after diarrhoea ; food does not taste right ; and loss of appetite in evening ; 10 to 11 p. m.

Nausea and vomiting after diarrhoea.

Vomiting of food ; of fluid while drinking, followed by faintness ; of what was eaten at supper, at night in sleep.

Vomiting throughout three days, with prostration and restlessness ; when vomiting ceased frothing began and nearly choked him (Pasteur).

Abdomen (Hydrophobinum)

A pressing pain : in right side, near last ribs, with breathing ; in hypochondria, after quick walking.

General soreness in whole of lower abdomen.

Inguinal glands very much swollen, they pain for two hours.

Pain in both groins ; in right, two small kernels under skin, very painful.

Painful throbbing as if an abscess was forming in region of spleen, but very deep in, exact locality is half-way between median line and outline of left side ; it lasted eight days ; with it departed remnant of a similar affection in this locality, against which eleven years of allopathic treatment had proved of no avail.

Rigidity of muscles of abdomen.

Tearing from left hypochondriac region to right

Stool and Anus (Hydrophobinum)

Diarrhoea : with much pain, most during day, eighteen hours after dose, lasting twenty-four hours, with pain in lower part of bowels ; < in morning ; followed by nausea as if she would have to vomit ; attended with violent pains early in morning ; after stitches in side.

Dysenteric stools with tenesmus ; renewed as soon as he hears or sees water run.

Involuntary stools.

Stools of bloody mucus.

Tenesmus during and after stool.

When in the morning some water was poured out from pitcher into basin, pain and desire to stool returned.

Urinary Organs (Hydrophobinum)

Constant desire to urinate on seeing running water ; urinates a little at a time.

Prostatic juice passes after urinating.

Urine too scanty and high-coloured (cured in a case of camp diarrhoea).

Male Sexual Organs (Hydrophobinum)

Atrophy of testicles ; testicles diminish in size, first left then right

Complaints resulting from abnormal sexual desire.

Glans is dry and sticks to foreskin.

Hydrocele.

Increased sexual desire (dropsy of spine with sheep ; hydrophobia of sheep).

Lasciviousness : after eating, with feeling of weakness in parts ; with erections in afternoon.

No emission during coition, but afterwards semen escaped unconsciously in sleep.

Priapism, with frequent seminal emissions.

Satyriasis in a stallion ; hot breath streamed from nostrils.

Semen is discharged too late or not at all during coition.

Sexual indifference with erections, even during act of coition, which is perfectly performed.

Strong erections, without sexual excitement or thoughts, in evening, while undressing in a cold room.

Female Sexual Organs (Hydrophobinum)

Any change of position that would tilt or rotate os uteri would cause much pain.

Both breasts swollen when waking in morning, she can hardly get up ; three mornings in succession ; same swelling of breasts at night when opening her dress.

During pregnancy : strange notions, desires or cravings ; rush of blood from chest upward ; toothache, backache and other complaints ; great sense of bearing down ; intense pain from inflammation of os and cervix (formerly treated with caustic) ; great soreness in lower part of back and bowels.

Increase of uterine sensitiveness, conscious of having a womb.

Pain in left ovarian region, uneasiness there.

Prolapsus uteri of seven years'' standing.

Sensitiveness of vagina rendering coition quite painful.

Severe leucorrhoea, with pains in back and lower part of bowels, sore vagina.

Since cessation of lochia a severe leucorrhoea ; pain in back and lower part of bowels ; soreness of vagina.

Spasms excited whenever she attempts to drink water, or if she hears it poured from one vessel into another ; sight or sound of water affects unpleasantly, even though desiring water (puerperal convulsions).

Weakness in back, with copious catamenia.

With a painful sensitiveness of womb, slight degree of prolapsus, so that after any considerable physical effort there would be a strong conviction that it was prolapsed.

Respiratory Organs (Hydrophobinum)

Breathing during paroxysm gasping, irregular and usually quite rapid, often with decided dyspnoea.

Breathing peculiar ; held for a time, and then a few rapid breaths (Pasteur).

Dyspnoea : with flatulency, cough and rattling in Chest ; with sighing, groaning respiration ; from cardiac pain ; < lying down.

Epiglottis crisp and dry (Rage).

Frothed at the mouth very much ; almost choked with it (Pasteur).

Oppression in breathing before a severe suffocative attack, induced by spasmodic contractions of respiratory muscles, combined with spasmodic, alarming constriction of pharynx.

Sighing, with pain in heart.

Voice altered in tone ; tones much suppressed ; hoarse ; rough ; harsh and weak (last stage) ; shrill, inarticulate sounds ; shrill sounds of utmost despair, or occasioned by violent expirations ; very shrill and piercing bark, changing near its termination into a distressing, continuous howl (dogs).

Chest (Hydrophobinum)

Chest and abdomen feel expanded ; expanding chest seems to invigorate him, though it usually fatigues.

Heart and Pulse (Hydrophobinum)

Heart had for three months not been free from a sticking, drawing, squeezing pain, result of an attack of rheumatism and cold, together with a palpitation and difficulty of breathing.

Heart palpitated violently and felt as if it was coming up into throat ; drank several mouthfuls of water, which relieved.

Pain in cardiac region, to which he is subject, is < half an hour after the dose, but much > in several days.

Stitches in heart from ringing of church bells.

Stitches in heart, < when walking ; they would kill him if they continued.

Violent pain in heart, as if it would burst or had needles running into it.

Neck and Back (Hydrophobinum)

Backache and headache.

Considerable pain in lower part of back, with soreness felt through to pubic region.

Pressing in neck and up back of head.

Limbs (Hydrophobinum)

Severe twitching in arms and legs, much resembling chorea.

Weight and heaviness of legs and shoulders.

Upper Limbs (Hydrophobinum)

Cramp in arms.

Hand trembles so much he can scarcely write.

Hands numb, with headache.

Right arm becomes so heavy and inactive that writing is too great an exertion, and he allows arm to drop.

The pain up arm was followed by cramps and drawing in back and limbs of bitten side.

Weakness in arms.

Lower Limbs (Hydrophobinum)

A pressive pain in right hip bone, goes from there to middle of sacral bones.

Along left sciatic nerve a dull pain, returning periodically ; < when rising from sitting.

Each dose he had taken made him feel as if he was getting corns on every toe, his real corns felt remarkably well and did not rain him at all.

Feeling as if hip bones would slip out of their sockets, > by resting hands on hips.

Left hip aches in bone.

Twitching in legs.

Weakness in legs when going upstairs.

Generalities (Hydrophobinum)

Acute ascending paralysis (Landry''s disease) diagnosed in early stage (Pasteur).

Bitten by a mad dog in sixth year in several places ; became somnambulistic ten years after.

Drawing from neck to forehead, immediately followed by sparks before eyes and vanishing of sight ; red face ; involuntary grinding of teeth ; second attack ; the first was felt in head after washing in morning ; seven days after bite of mad dog (Bellad. , three doses, Hyos. interpolated once a day).

Makes a peculiar noise like a waggoner driving horses (Pasteur).

Prostration beyond description (Pasteur).

Severe nervous twitches in whole body all day.

Twitching every few minutes ; sometimes more violently than others ; most marked in abdominal walls (Pasteur).

Twitching of muscles throughout entire body (Rage).

Twitching of tendons with tendency to general convulsions (Rage).

Skin (Hydrophobinum)

Biting, itching in various parts of body, < by scratching.

Bluish discoloration of bitten place (after Laches).

Cancerous sores.

Dark, livid-marks where inoculations were made ; pricking sensation in them, causing him to continually press his side, which relieved temporarily (Pasteur).

Malignant ulcers from bite of a dog.

Pustules on forehead ; around inflamed eye ; on finger (after bite).

Quick tendency of the wound to heal (the same in leprosy).

Red scar from bite of a dog.

Sleep (Hydrophobinum)

Frequent yawning without sleepiness, particularly when hearing others yawn.

In morning, after exciting dreams, much fatigued, feels tired in sacrum and back.

Inclination to yawn, with stiffness of lower jaw.

Insomnia ; sleepless in spite of narcotics (Rage).

On awaking from siesta numbness in head.

On waking is morose, inclined to be angry.

Starting in sleep, afternoon.

Fever (Hydrophobinum)

At 9 p. m. a dripping warm perspiration from whole right hand, from wrist to nails ; afterwards hands and fingers stiff, she can hardly bend them (Rage).

Became cold in bed at 3 a. m. , although covered with four blankets ; lasted about one hour.

Cannot bear heat of sun.

Chills intermixed and followed by heat and cold sweat.

Chilly feeling, more down right (bitten) arm.

Fever every evening, commencing at dusk and lasting until bedtime (midnight).

He feels the pulse beat through the body ; from time to time there is a surging through throat into head, like a slow wave.

Intermittent fever.

Much better after perspiring.

Paroxysms of intense coldness with pain in spine.

Restless, skin cool, perspiring, quite conscious (Pasteur).

Sensation of heat felt internally and externally through entire body, no external warmth, it forces perspiration out on face as from weakness, and is accompanied by lassitude and aching in legs.

Skin covered with a clammy sweat (last stage) (Rage).

Skin moist, even covered with sweat ; during spells, limbs cold and livid.