This substance, which has been used for some years past as manure, is found on the coasts of Patagonia — and princi- pally on the Lobos Island near the coast of Peru. We have proved the different varieties of guano, and likewise the crys- talline particles formed by the condensation of ammonical vapors which rise from the guano in abundance. Our hope to discover in these crystals a more active normal agent, has not been realized, so that, in the end, we have found the freshest possible guano preferable for medicinal purposes. It is triturated in the same way as all other substances. First day. — 1. Internal shuddering for three minutes in the morning. Violent headache. Pain in the forehead when inclining the head forward, at 6 o'clock in the morning. Vio- lent itching at the back, and painful smarting after scratching, at 7 o'clock in the morning. 5- Formication in the right nasal fossa, at 7 and a half o'clock. Pain with pinching behind the ears, at 8 o'clock in the morning. Dizziness, objects turn from below upward, at 9 o'clock in the morning. Nausea wiih profuse flow of saliva. Pale face with faint feeling, at noon. 10. Lassitude, at half past two in the afternoon. Desire to vomit, at half past two in the afternoon. While eating, pain at the pit of the stomach and desire to vomit. Profuse sweat all over, after eating. Aching in the forehead and temples, worse when stooping, at half past three. 15. Pain at the styloid process of the left wrist. Pain in the lungs which stops the breathing, for three minutes. GLJANO AUSTRALIS. 55 Swelling of the right index-finger. Itching of the genital organs. Water feels extremely cold to the hands, they feel like ice when keeping them in the water a little longer. 20- Pain at the feet which prevents one from pressing them to the ground, at 5 o'clock in the evening. Red spot, with itching at the back, and smarting pain after scratching. Vio- lent headache as if the head were incased in iron. Second day. — Beating at the left commissure of the lips, at 6 o'clock in the morning. Itching in the right nostril and frequent sneezing, for one hour, at half past G o'clock. 25. Great weakness. She remains at the spot where she hap- pened to have located herself. Third day. — Painful ganglion on the left arm, with redness and itching ; when scratching the arm, it remains insensible until the skin was off; lasts for half an hour, at 6 o'clock in the morning. Headache : he feels as if the head were open- ed, at 8 o'clock in the morning. Smarting ganglion below the right calf, hindering walking, and lasting until night. Fourth day. — 30- Nausea, one cannot bear seeing persons eat, at 7 o'clock in the morning. Painful ganglion at the left elbow. Small itching pimples. Violent beating of the heart ; feeble breathing, for five minutes. Large hard and red place on the back, with pricklings as from a thousand pins. This sensation commences at 9 o'clock and lasts all night. Fifth day. — 35- Profuse sweat on the arms and hands ; the skin on the thighs is insensible ; a prick is not felt ; for two days they are covered with little pimples. Cramp at the pit of the stomach before eating. Sixth day. — Violent pain at the right knee, as though pieces of fiesh would be torn from him, at 7 o'clock in the morning. Burning under the soles of the feet, she cannot keep her shoes on. Cramp at the left thumb, for an instant. Seventh day. — 40. Sensation as if the gums were cut with pen-knives, after which thoy bleed for half on hour, at 6 o'clock in the morning. Formication in the right nostril, for five minutes, at 10 o'clock. Sensation of hammering in the nape of the neck, at o o'clock in the afternoon. Pain in the 56 BRAZILIAN PATHOOENESIS. abdomen as if pierced by sharp points, at 9 o'clock in the evening. Eighth day. — Tongue white and thickly coated. 45- Bitter bilious taste in the mouth, at 6 o'clock in the morning. Deep sleep. She dreams that she is playing with wild beasts. ARRANGEMENT ACCORDING TO HAHNEMANN. HEAD, &c.: 1. Dizziness, objects turn from below upward.