It has been proved in large! doses, and its most prominent symptoms Are: Trembling of the body. Prostration and trembling. Swollen sensations of face and body. Swelling of hands and feet; showing its relation to dropsical states like Apoc. can. and Stroph. Heaviness with great desire to sleep. Flying pains in different parts. Itching of body and face. Acute rheumatism with great stiffness. General rheumatic pains. Profuse sweat of whole body. The pains go from above downward; are < when breathing; and on turning to left side. Hale has cured with it rheumatic gout: "Acute pains in the joints attended with cramps, bilious stools and flying pains in the teeth. The tincture in drop-doses has been known to expel ascarides and other worms." It has been used for expelling renal calculi and gravel.