Another spider which Grauvogl classed with his so-called hydrogenoid remedies, i. e., the patient always suffered, with whatever she had, most in wet weather. It is well to remember such positive modalities, for it may narrow down the case to a few remedies from which our curative must be chosen; for instance -Aranea, Natrum sulphuricum, Dulcamara, Nux moschata, Rhus toxicodendron, Rhododendron- all have these wet weather aggravations, and we will be apt to find our remedy there if the patient is characteristically worse in wet weather.