We had no provings of this very important combination until 1847, when C.Hg prepared and proved it. What is given in Allen's Encyclopaedia are accidental poisonings, which mostly prove fatal. The only clinical ex- periments have been made by Doctor Drysdale, in ]849, in the treatment of Asiatic cholera. Laboring under the mistake that Arsenicum was a spe- cific in Cholera Asiatica, and supposing to get something more powerful in the arsenetted hydrogen, he altogether overlooked that, notwithstand- ing its sudden action, it would not correspond to subacute ailments, on account of the very slow development of its symptoms. Nearly all per- sons poisoned even by small doses died in the second week. The only one that recovered, suffered for seven weeks. The only real cure on record is the one published by F. W. Payne, in the New England Medical Gazette. The similarity of some cases of Asiatic Cholera with the symptoms of the common arsenic is, according to Hahnemann's advice to Stapf, in 1813, regarding Niix vom. and Ignat., too great. They are no antidotes. The authorities quoted in Allen's Encyclopaedia are: 1. Gehlen, Buch- ner Tox., 1827 ; 2, R. Schindler, Grsefe and Walther Journal, Vol. XXVI, No. 4, p. 626 ; 3, Eisenmenger, Zeit.fur Horn. Kl., No. 1, p. 103 ; 4, O'Reilly, Duh- Uh Journal, 1842; 5, Ollivier, Gaz. d. Hop., 1863, to which we add the case of J. E. Bullock, died on 12th day, at Dr. Beard's, (Gmelin, Chemie II, p. C90), and the reports of Dr. Richardson, in Calcutta, and some remarks of Berzelius, Bennecke and others. Provers are marked, C.Hg., Hm., N.N., F.K., Rh., Ea. In this instance we depart from our usual rule of omitting the names of the provers from the arrangement of symptoms (which would swell the book to too large a size) on account of the provings of Arsenicum hydrogenisatum not having been published. The — signifies that the symptom is mentioned somewhere else. ^ Mind. Almost unconscious. — R.Sch. He lost his memory on the evening of the 6th day. — Br. He afterwards can hardly remember the transient pains ; 1st d.— C.Hg. His mental powers are unimpaired from the first. — Br. Great exaltation of mind ; it made him talk incessantly. — R. Sch, lExcited; wants to talk constantly. ^ Yellow fever. Loud complaining about unbearable pains in spine. — Impeded in talking, he answers very slow. — Disinclined to work. — Eisenmenger. His occupation is disgusting to him. — F.K. 99 ARSENICUM HYDROGENISATUM. Lazy and shirks his work. — C.Hg. Full of care and fear about his complaint when he gets awake at night.— F.K. Afraid of being alone, he thinks he will die. — F.K, The fear of dying is gone on the 3d day, notwithstanding all around him have doubts of his recovery. — R.Sch. Anxiety, he believes his death is near, and despairs of being better (during the vomiting), more courage afterwards, till the next vomiting turn (6 hours). — R.Sch. Anxiety, with constriction of chest. — Chemists. Anxiety, restlessness and great prostration of strength. — Robe- son. Anxious feeling before the chill. — Indifferent on hearing the most important news ; discouraged, changeable, his mental activity much impaired all week. — Soporous and apathic ; conjunctiva injected ; urine red and scanty; 3d. — O'Reilly. He is vexed, impatient, anxious about his complaint and full of fears.— F.K. When thinking about his headache he feels it least ; 1st day. — Thinking of water irritates him, as if he would have to vomit; it nauseates him. — * Sensorium. Vertigo, with oppression of chest. — Grmelin. Vertigo, violent, on going up stairs, so that he staggered against the sides of the stairs ; was not noticed on going down stairs, or on a level floor; 3 hours. — R.Sch. Vertigo and general weakness. — O'Reilly. Immediately after the second inhalation, vertigo with faintness, followed by shuddering and a passage from the bowels and a painless discharge of two ounces of blood from the urethra. —Br. Vertigo with nausea and vomiting. — A swimming sensation in head and whole body. — F.K. Vertigo with headache. — A giddy oscillation with pressure in the frontal sinuses. — Head dull and benumbed, with pressure in forehead. — Heaviness of head. — F.K. During the night a pressing, stupefying sensation in head, like from a load, with a tearing sensation ; sleeplessness all night ; applied cold bandages without effect ; pain lessened towards morning. — R.Sch. ■ Stupefying feeling in head, as of a load there. — F.W.Payne. Above the forehead to the right, a giddy sensation, with an in- ner twitching, like a painful quivering of muscles ; soon af- ter, the same feeling in upper and lower jaw, going down in a straight line ; later, the same in right shoulder. — C.Hg. ARSENICUM HYDROGENISATUM. 100 ^ Inner Head. Pressure in right frontal sinus, like with the point of a little finger ; later, the same on the left. Pressure above the eyebrows, with numbness, in the afternoon. — F.K. Violent pressive frontal headache, worse at-night, and with such excessive weakness, that he was obliged to lie in bed for several hours after eating ; 1st and 2d days. — Eisenmenger. Violent headache in forehead. — Ollivier. Pressure in right temple, with flabbiness in stomach ; after two or three minutes the same sensation in left temple. — Now and then a headache in two streaks, from behind to front, would be unbearable if continuing ; >■ when thinking about it.— C.Hg. Transient pains in the head. — Head and toothache, <C in warmth. — C.Hg, Pain in right forehead and head. — C.Hg. Pain in occiput, <C on the right and when coughing. — Headache in upper and back part of head when coughing. — Toward evening headache on right side, extending down into the throat near larynx. — F.K. Pain in forehead with the chill. — Headache increased during the chill. — Eisenmenger. Violent pain in forehead and in sacrum. — Ollivier. Pain in head and epigastrium, followed by vomiting of food. — Ollivier. After 10 P.M. headache increasing, face more red ; conjunctiva injected; pulse strong; speech impeded, answers slow. — Ollivier. Dura mater unchanged, arachnoidea a little injected, and below it air-bubbles ; in the substance of the brain bloodless spots ; no water in the cavities. — Br. * Outer Head. All the hair on the "deadened" parts become snowy white, and the white brows formed a strange contrast to the dark brown face. — R.Sch. ® Sight and Eyes. When falling asleep and again when waking up at night, a blue light before the right eye. — F.K. Like a thread floating down before the right eye ; later, a dim- ness.— F.K. Eyes yellow, deeply sunken, with broad blue circles. — Sch. Eyes sunken, lustreless ; conjunctiva bulbi red. — Eisenmenger. Conjunctiva reddened; with the chill; in the evening; again on the 3d day. — Heaviness of the lids, have to be lifted up with the fingers. — Rh. A deadened feeling in region of eyebrows, the brows turn snow white, forming a strange contrast with the dark colored face. —R.Sch. 101 ARSENICUM HYDROGENISATUM. ^ Smell and Nose. Tickling up in the nose, right side, causes sneezing. See 15. Indescribable sensation up in the nose. — N.N. Unpleasant crawling in the nose causes sneezing. — R.Sch. Violent sneezing, and such coldness of nose that it must be wrapped up in warm cloths. — R.Sch. Nose as if deadened. — R.Sch. Nose feels as if dried up. — F.K. Bloody mucus comes from the nose. — F.K. Nose somewhat sore, with the chill. — Nose and lips somewhat excoriated. — Eisenmenger. " Face. The yellow eyes deep sunken, with broad blue circles. Painfully distorted features. — Sch. The face, which changed within a few hours to dark brown, was on the 5th day still dark yellow, and the features dis- torted as from great inward suffering. — The face copper-colored, or dark red, the body greenish-yellow. —Br. Yellowish face at beginning of chill. — Face pale, lips discolored, can hardly walk ; in 3 hours. — Olli- vier. Face earthy, dull, stupid features ; skin dry ; pulse 107 ; vio- lent thirst, with a dry tongue ; 2d day. — Ollivier. Changed, sick face, sunken, cheeks yellowish ; 5th to 7th day. —F.K. Looks disturbed and pale. — C.Hg. iThe face looks old, and bears an expression of pain. — F.W. Payne. In the face chilly feeling, followed by a glow. — Heat in the face. — Bennecke. Face red in the evening. — Sweat in large drops on face and whole head. — Face oedematous ; 5th till 7th day ; worse in the evening. — Br. iFace greatly changed. ^Yellow fever. ■ Countenance wears an expression of extreme anxiety, d Col- lapse of cholera. ^ Lower Part of Face. In upper and lower jaw a very painful twitching ; pain going from above downward in a straight line.— C.Hg. Pain in maxillary joints, when first opening the mouth, when pressed with the finger, when putting the tongue out.- -F.K. Lips colorless. — Ollivier. Upper lip sore, with the chill. — Lips and tongue fuliginous, furred ; 5th day. — Ollivier. ^° Teeth and Gums. Toothache < in warmth. — I Sore bleeding gums around the remaining root of the right upper incisor. — C.Hg. ARSENICUM HYDROGENISATUM. 102 ^^ Taste, Speech, Tongue. Taste bitter. — Eisenmenger and O'Reilly. Bitter taste in mouth after 4 hours vomiting, with great pros- tration.— Br. All sweet things taste too sweet.— ^F.K. A peculiar indescribable taste in mouth. — C.Hg. Very unpleasant sticky after-taste, lasting for hours after eat- ing, the whole week. — C.Hg. A contracting sensation of numbness, like a cold feeling, in half the tongue in front, right side, with running together of saliva in the mouth ; weakness in abdomen and pinching ; 1st day. — C.Hg. Pricking on tip of tongue and tickling in nose, upper part, right side, inducing sneezing; 1st day, evening. — C.Hg. Tongue slimy, evenings. — Tongue yellow. — Eisenmenger. Yellowish, furred tongue, with the chill. — Tongue: bluish-white, thinly covered ; slimy taste, no appetite ; later, grayish-white, worse on back part of tongue ; still later, tongue white and soft. — F.K. Tongue fuliginous, furred. See 9. Tongue somewhat enlarged, on the right a deep irregular ulcer ; next day a second nodular swelling of a darker color coming to a point. — Br. Tongue dry, with violent thirst. ^^ Inner Mouth. Mouth hot and dry, with very little thirst ; dur- ing the heat. Running together of saliva in mouth. See 11. ^^ Palate and Throat. Burning and constriction in throat, fol- lowed by irritability of stomach. — Robertson. ^* Appetite, Thirst, Desires, Aversions. Less appetite on ac- count of slimy taste in mouth ; eats without relish. — F.K. No appetite in the evening, tongue slimy. — Very little appetite the whole second week. — Appetite very poor. — Eisenmenger. iLoss of appetite. — F.W.Payne. Hunger the first evening. — C.Hg. Violent thirst in 3 hours. — Ollivier. Violent thirst and a dry tongue. — Much thirst the 2d day, drank oatmeal gruel, milk and slimy drinks in large quantities. — Sch. Great thirst the 5th day, less the next following night. — Br. Thirst with the afternoon fever. Very little thirst with the fever heat. More sensitive to tobacco ; 1st day. — C.Hg. Smoking without relish ; 8th day. — F.K. ^^ Eating and Drinking. After eating, frontal headache. — 103 ARSENICUM HYDROGENISATUM. A few hours after dinner he had to lie down in bed on account of headache and weakness. — ■ Constant retching and vomiting after taking the least thing to eat or drink. ^Yellow fever. ^® Hiccough, Belching, Nausea and Vomiting. Belching, with the taste of the food eaten ; a slimy tongue and no ap- petite evenings ; smoking tasteless. — F.K. Eruptions. — Eisenmenger. Spasmodic eructations of enormous quantities of tasteless gas from\tomach, without relief of pain in abdomen, that causes him to moan for six hours. — Sch. ■ Uninterrupted belching up, spasmodically, of a large quantity of tasteless air, with great pain in abdomen, d Yellow fever. During spasmodic eructations without any interruption, an in- credible large quantity of tasteless air is expelled from stom- ach without relieving the pain in abdomen. — El. Sch. Hiccough following the eructations; Sd'day. — R.Sch. Annoying hiccough the 1st night, returning 3d day. — Br. Tormenting hiccough, with an oversensitive epigastrium. — Br. 1 Very troublesome and annoying hiccough, d Yellow fever. Nausea. — Berzelius. Nausea and vomiting, with vertigo and constriction of chest. — ■ Nausea. ^ Yellow fever. Complains about nausea and fullness in epigastrium ; 6th day. —Br. Incessant retching and vomiting. — Gehlen. Retching and vomiting even after a single swallow, even a little water is followed by a return of the most painful retching and vomiting. — Gehlen. Vomits everything taken into the stomach. — Gehlen. ' Violent vomiting, could not retain the slightest thing. — O'Reilly. Ollivier. Vomiting of green, bitter mucus with the colic. — Sch, ■ Vomiting of mucous, yellow, green and bitter fluid, d Yellow