This remedy exercises a profound action upon the mind and body. The patients suffering from latent syphilis are over-sensitive to it, and often require it in their complaints. It has many bone symptoms and pains and they are worse at night. Its catarrhal condition is very much like that found in old cases of syphilis, such as had long treatment with Mercury and Iodides. it is a rheumatic constitution also and is useful in acute and chronic rheumatism. It has cured rheumatic fever where the joints have been mostly affected but are now better and the heart is the principal seat of suffering. Many complaints are associated with cardiac disease. Dropsical states from heart disease, from liver affections, with albumin in the urine after scarlet fever or with intermittent fever. Where old syphilitics continue to lose flesh. The glands and parts inflamed become indurated. It has been useful in cancerous glands. Inflammation of the bone and periosteum; caries, exostosis after Mercury in latent syphilis. Caries of the joints with nightly boring and gnawing pains. It has burning pains in many parts. The pains are tearing, drawing, pressing and stitching. Many symptoms come on during rest and some during motion.