Lepelletier has recorded the following effects of 0.02 to 0.90 of a gramme of Brucinum. Sudden jerking, especially of lower extremities, spreading generally but not accompanied by trismus and tetanus, and not extending to Oesophagus and pharynx as with Strychnia. Twitching in the paralysed as well as healthy muscles. A fever of short duration ends the attacks; after which deep sleep comes on.