We are indebted for this very valuable medicine to the wife of Dr. Ru- bini in Naples. Admiring the great beauty and sweet odor of the flower, and knowing its short life, opening at evening, closing and dying before dawn of day, she induced her husband to make a preparation from the young flower, from which is their masterly proving, which will be a boon to suffering humanity to the end of timo. In 1864 Rocco Rubini published his monograph, and in 1865 Dr. A. Lippe published the first correct and complete translation of it into English. All other translations into English and German are full of errors and omissions. Later prov- ings have been made by Hencke, Lemke, especially by Barnes Horn. Ob- server, Vol. 3, p. 78, 1860. Same year some symptoms were observed by C.Hg. and G. Bute. ^ Mind. General stupidity. Difficulty in finding right expression when writing the symp- toms down. ■ Thinks she will not recover. ^Rheumatism with heart disease. I Feels she is dying and thinks she will not live till morning, but has no fear of death. ^Rheumatism of heart. I I Love of solitude. I I Irresistible inclination to cry (an intelligent woman). I I Cries, knows not why ; consolation aggravates. ■ Screaming with pains, with complete consciousness. ^Rheu- matism with pain in heart. Taciturn, unwilling to speak a word or to answer. ■ Cheerful and vivacious. ^Heart disease. ■ Sadness, taciturnity, and irresistible inclination to weep. Invincible sadness. I I Hypochondriacal. ■ Fear of death ; he believes his disease incurable. Indescribable fear that something terrible is going to happen to him. ■ During and after attack, great anxiety, fearing some organic lesion of heart which will cause sudden death. ^Angina pectoris. Anxiety returning in the evening. ■ Despondent. ^Rheumatism with heart disease. ■ Easily frightened, often awakes in a fright. ^Enlargement of heart. 59 CACTUS GRANDIFLORUS. Felt much alarmed on waking, but could not tell the cause of . alarm. ^Sensorium. I Vertigo from congestion; face red, bloated ; pul- sation in brain ; madness, anxiety. ■ Vertigo; < from physical exertion, turning in bed, stooping, rising from a recumbent position, and deep inspiration. ^ Inner Head. Heaviness of head. A numb pain with a stupefied feeling, extending from above eyes across base of brain. Pain in forehead and eyes, with ringing in ears. Stinging pain in forehead over eyes. ■ Pulsation in temples as if the skull would burst; intolerable at night. ■ Pain in r. temple by spells, brought on by a glass of wine, by attending opera, or after getting dinner at too late an hour. Congestion to brain, blood-shot eyes, coma, suffocation, flushes in face ; fever, from exposure to sun's rays. ■ ■Heavy pain like a weight on vertex; > by pressure, but < from sounds, hearing talking, or strong light. ■ ■Right sided headaches and neuralgias which are periodic, pulsating and throbbing, and of extreme type. ■ Pulsating pain, with sensation of weight in r. side of head, continuing day and night, so severe as to make him cry out. ■ Heavy pulsating pain in head. Troublesome pressure in r. parietal bone ; later pain in 1. pa- rietal bone, early on rising. ■ Pain and pressure on vertex, with palpitation and sensation as if heart was grasped. ^Coryza. ■ Tensive pain on vertex. ■ Feeling as if head were compressed in a vice and that it would burst open from severity of pain. ■ Something seems to be whirling up from chest to brain and all arteries seem to throb; feels as if dying. ^Rheumatism of heart. I I Headache from noise and light. ■ Headache commences in morning and grows, as day advances, to an unendurable height, with vomiting. Excessive pain in head, so anxious he cannot remain in bed ; prostrated, weak. Headache m different parts of head; < from motion and deep inspiration. ■ Headache from sanguineous congestion or rheumatism. ■ I Cerebral congestion. ■ ■Sanguineous apoplexy. * Outer Head. ■Pain in r. temple coming in spells; begins in morning, increasing during day, with vomiting ; nose con- stantly dry; must lie perfectly quiet; < from keeping up, noise, light or exertion. CACTUS GRANDIFLORUS. 60 Pressive pain in 1. parietal bone, rather external. Painful drawing in aponeurotic covering of occiput ; > bend- ing head backwards. I Cold, clammy sweat on forehead, upper and lower limbs. ^Cardiac rheumatism. ^ Sight and Eyes. ■ Sensitive to light. ^Headache. Dimness of sight from circles of red light before eyes. At a short distance he cannot recognize a friend Dark spots before eyes, with pain in forehead and eyes. iDimness of sight; cannot see at a distance; objects appear to be obscured. Weakness of sight returning periodically. Sight blurred. I Eyes blood-shot; cerebral congestion even to coma, when perspiration fails. ^Intermittent. I Acute rheumatic ophthalmia. Hyperaemia of eye, especially of fundus. ■ I Exophthalmic goitre. ^Heart disease. ^ Hearing and Ears. Worse from sounds, even talking ; heavy pain like a weight in vertex. I I Singing or ringing in ears. Hardness of hearing from congestion ; pulsations in ears; noise like running water or buzzing. Hearing diminished by buzzing in ears. ■ Pulsations and buzzing in ears. ^Otitis. ■ Rheumatic otitis. ■ Otitis from checked perspiration. "^ Smell and Nose. Fluent, acrid coryza ; nostrils sore. ■ Dry or fluent coryza. Dry and unpleasant coryza; must lie at night with mouth open. ■ Constant dry nose. ^Headache. ■ Profuse nosebleed, soon ceasing. ^Tipper Face. ■Prosopalgia, right-sided, chronic; < from slightest exertion, tolerable only when lying still in bed ; brought on by wine, music, strong light, or missing dinner at usual hour. ■ Flushes of heat in face, with suffocation. ^Intermittent. ■ Face bloated and red, with pulsation in head. ■ Paleness of face and emaciation. ■ Pale, death-like countenance. ^Cardiac rheumatism. ■ Anxious look, pale face, purplish lips. ^Cardiac rheumatism. ■ Blue face, with chill. ^Intermittent. ■ Face and head swollen and discolored. ^Heart disease. " Taste and Tongue. Taste acrid. ■ Loss of taste for food, with nausea. ■ Tongue purple, with thick brown sordes on teeth. ^Low