The most important feature of this medicine is the inflammatory condition, and the most important characteristic in the inflammation is the rapidity with which it develops into a gangrenous state. inflammation conditions usually follow a definite course for days, but when this medicine is put upon a part or taken internally the inflammatory state terminates in death of the part with great rapidity. When taken internally it proceeds almost immediately to attack the urinary tract and establish a uraemic state which brings about the mental symptoms; the local inflammatory condition comes on with great rapidity, and this brings the patient down violently sick in a great hurry. From strong doses in the poisonous effect we get startling and alarming symptoms; the whole economy is in disorder; grievous symptoms commonly of the urinary tract. The parts become gangrenous at an early stage.