Colchicum is best known as a remedy in gout and rheumatism, and the provings show its specific relation thereto. It acts on muscles, bones, and joints. It causes extreme relaxation of the muscular system—the head falls forward on the chest; or falls back when the patient is raised from the pillow; arms fall helpless by the side. Stitching, jerking, drawing pains in muscles; periosteum, and joints. Extreme disinclination to move; < from motion. Mind befogged; but answers correctly. Absence of apprehension, no fear of death. Results of getting wet and Letting chilled; changes to damp weather; autumn dysentery, spring rheumatism. (The flowers of the plant appear in autumn; the leaves not till the following spring.) It corresponds to the gouty constitution; leuco-phlegmatic and melancholic temperament; venous constitutions; uric acid diathesis, the sediment being pale yellow and rather like fine flour than sand. Also, urine black as ink; urine loaded with albumen and casts. There is the irritability and aversion to touch so common in gout; pain in small joints, and especially the great toes. The stomach is acutely disordered, nausea and vomiting. "Nausea at thought, sight, or smell of food, especially of cooking," is a characteristic symptom. (Nash records a striking cure by Colch. 200, to which he was led by this symptom. The patient was an old lady who was vomiting blood, and passing as many as sixteen bloody stools in the day. The doors of the room had to be most carefully kept closed to prevent any smell of cooking reaching her as that immediately provoked nausea.) Sensation of icy coldness in stomach; or burning. Coldness is a common symptom: abdomen; stomach;