The well-known emetic effect of Ipecacuanha Wine gives a rough keynote for the use of Ipec. in homoeopathy. Wherever ailments are associated with the presence of constant nausea Ipec. is very likely to be of use. The special form of nausea is a constant but unavailing desire to vomit; or immediately after vomiting there is, instead of relief, a desire to vomit again. With this there is a clean or not very dirty tongue. There is profuse salivation with the nausea. The nausea of Ipec. is oftenest met with in affections of the stomach and bowels, of the respiratory organs, and in fevers. In the stomach itself there is a symptom which is very characteristic of the remedy, a feeling "as if the stomach were hanging down relaxed." There is disgust at the stomach for food; empty vomiting; vomiting of bile; of blood. No > by vomiting. The stomach disorder may be occasioned by rich food-pork, pastry, fruits, candy, ice-cream. The stomachic disgust of the remedy is depicted on the countenance, which expresses nausea. The corners of the mouth are drawn down. Blue rings round the eyes. Sometimes the mental state corresponds: "Moroseness and contempt for everything"; "Disdainful humour." The irritability of the elders becomes in children crying and screaming. Another mental symptom is "full of desires they know not for what." Ipec. is a botanic relative of China, and it is also an antidote to the latter; (it is also closely allied to Viola odorata). Perhaps the relationship of Ipec. to China may have something to do with its large sphere of usefulness in intermittent fever. Jahr recommended that in all cases of intermittents in which no other remedy is particularly indicated Ipec. should be given to begin with. It will either cure the case or bring out more definitely indications for another remedy. I have frequently found this advice useful; and it occurs to me that as most intermittents have been treated with quinine it is through its antidotal properties that Ipec. exerts some of its good effects. It has a strongly marked periodic action. A special indication for it is: Nausea through all the stages. Other indications are: "Stages completely mixed up short chill, followed by long fever." Ipec. has many bone pains, in the head and elsewhere. Pains as if bones were all torn to pieces. Ipec. is given as an expectorant in old-school practice, and is supposed to act by its nauseating properties. But homoeopaths have proved that nauseating doses are neither necessary nor desirable. The cough of Ipec. is dry, spasmodic, constricted, asthmatic. "Violent degree of dyspnoea, with wheezing and great weight, and anxiety about the precordia." "Threatened suffocation from accumulation of mucus." In whooping-cough a characteristic is the spasmodic rigidity of the patient. "Child loses breath, turns pale, stiff, and blue; strangling with gagging and vomiting of mucus; bleeding from nose or mouth." The great keynote, subject to slight variations, is—mental depression with tissue irritability. The tissue irritability of Ipec. is severe and urgent, but superficial; that of Ars., deep-seated, diffuse, and burning; that of Ferrum involves tissue, as with Ars., but is mostly painless (Cooper). Ipec. is a medicine of great importance in haemorrhages. The blood is bright red and the flow steady. A grand keynote for Ipec. in haemorrhages (whether of lungs, bowels, uterus, or other parts) is nausea with the haemorrhage. Guernsey thus describes the effect of Ipec. in the female sexual sphere, in which the haemorrhagic power of the remedy is of the highest importance: "Threatened abortion; often with a sharp pain around the umbilicus, which runs downward to the uterus, with constant nausea and discharge of bright red blood; discharge of blood before the proper period; metrorrhagia, often after confinement, which is heralded by a low pulse, nausea, &c.; there is a steady flow of bright red blood, which may soak through the bed to the floor, or may run over the foot of the bed. (Where there is this steady flow of bright red blood give Ipec., and do not resort to applications, manipulations, &c.) Menstruation too early and too profuse; deficient labour pains, and with the pains there is a great deal of suffering, but no good is accomplished, the suffering is caused by the above-named pain about the umbilicus, moving to the uterus." Some of the pains of Ipec. run from above down; some from left to right (cutting pain in abdomen). There is a remarkable headache "as if bruised, all through the bones of the head and down into the root of the tongue." Nausea is generally an accompaniment. Brain feels bruised, pain piercing to roots of teeth. There is also a sick headache originating in the stomach, the nausea preceding the headache and persisting all through. Teste has used the remedy with good effect in "constrictive and contusive headaches seated in left parietal region, coming on every day at 11 a.m., increasing gradually until the pain became intolerable, then decreasing in the same manner" and ceasing completely at 2 p.m. Another sphere in which Ipec. has shown great curative power is the eye. According to Allen granulations of the lids have been cured by the instillation of the dilutions. Also subacute inflammation of the cornea, with intense pain and great photophobia. Pustular conjunctivitis, especially in children. Inflammation with tearing pain and gushing of tears. Violent neuralgia of eyeballs, shooting in the head, with gushes of tears, nausea, &c. Dr. Nancy T. Williams (H. R., xi. 65) has cured several cases of gall-stone colic with Ipec.