This remedy is an antipsoric and antisyphilitic. It has been used very extensively by the old school as an antisyphilitic, but in the very large doses which they used it became to a great extent allopathic to the disease, because of the tremendous effect it produced upon the economy, and implanted its own miasm, and thereby in a measure it suppressed many cases of syphilis. The medicines that are the most powerful substances are really those that sustain in homoeopathic relation to the disease in general, and of these the very smallest dose often cure when similar. When the remedy is not similar enough to cure in such a form the increasing of the dose does not make it homoeopathic. There is an idea in vogue that increasing the dose makes the remedy similar. That is going away from principle. If the remedy is not similar there is no form of dose that can make it similar. It affects the glandular structures and the periosteum after the manner of syphilis. It produces catarrhal inflammations. It is a deep-acting medicine and closely related to Mercurius. It has ulcerations and catarrhal states and glandular affections like Mercurius. It is similar in its action to Mercurius and is an antidote to it. The old subjects who have always been taking Calomel or Blue Mass for their bilious complaints will in time become subject to frequent coryzas, constipation, pains and aches, and disturbance of the liver, and disordered stomach, and must have another dose of Mercury. Some of these cases need this remedy. If you practice medicine in a neighborhood where there is a very poor homeopath you will find that he is giving the Biniodide, or some other preparation of Mercury, for almost all of the colds or sore throats. This establishes upon all of these patients an over-susceptibility to the weather changes, and they keep taking these red mercurial powders. Some of them carry them around in their pockets. But the more they take of these red powders the more frequently they have sore throats and colds. Many times they will not get over these troubles without Kali iod. in potentized form, or Hepar. Hepar and Kali iod. are the two principal medicines that such patients need. Individuals with this susceptibility to colds and sore throats and weather changes, that is, from the effects of Mercury, who have been led into a Mercurial state, run two ways, Those who are invariably shivering and cold, and want to hover around the fire, and cannot keep warm, will need Hepar, and those that are always too warm, that want the covers off, and want to be in constant motion, extreme restlessness, very tired when keeping still, will have their Mercury antidoted by Kali iod. The Mercurial state will be antidoted, but it sometimes takes several prescriptions and sometimes a series of carefully selected remedies. The psora, that is, his chronic state, will not manifest itself until you have lifted off this miasmatic state, which has been caused by Mercurius. It is astonishing what a great number of men, women and children are bowed down by the miasm that Mercury produces, and yet those prescribers go on, giving this form of Mercury and say it is practicing Homoeopathy. I am led to remark that there is yet much to be learned about the art of prescribing.