To Dr. Samuel Swan is due the credit of first recognizing the possibilities of this substance when potentized, from reading the reported successful use of it in the crude form by Donkin, in the treatment of diabetes, albuminuria and other affections of the kidneys. He potentized it and began the proving on himself and a lady patient whom he had cured of a chronic ailment with the m. and cm. potencies. Subsequently he induced Dr. Laura Morgan to undertake it, who with her friends made extensive provings, and what is remarkable is that the genuine character of the original work has not only verified many of the claims of Donkin, but nearly every symptom in the pathogenesis has been clinically verified, especially the peculiar headaches, obstinate constipation and the unusual and irregular menses. It is well known that the chemical constituents of milk contain an epitome of the salts and tissues of the animal which secretes it, hence we may conclude that its range of action is co-extensive with these tissue salts. Here we find the " mental depression and weeping," the "thirst for large quantities and often," the "periodical headache increasing and decreasing with the sun," the "obstinate constipation and fissure pain " of Natrum muriaticum. And so of other salts. Grauvogl suggests that hydrogenoid and cold children should not be given milk, and Burnett maintains that a milk diet, even skimmed milk, after the first year renders them susceptible to colds. There is no doubt it prevents nutrition in many persons, both children and adults, developing emaciation in some and obesity in others ; in other words, a constitutional diathesis akin to, or that tends toward, the tubercular. The deep-seated vein of nervous phenomena manifested in its pathogenesis and verified in the care of many obstinate chronic ailments warrants a more careful study of this little known and less used remedy. Mind (Lac Vaccinum Defloratum) I Depression of spirits ; don't care to live ; question as to quietest and most certain way of hastening one's death. I Depression of spirits which is not dissipated by conversation. I Head light, with throbbing in temples. I Imagines that all her friends will die and that she must go to a convent. Can remember what has been read only by a strong effort of will. Depression and weeping with palpitation. Does not want to see or talk to any one. During conversation, headache and depression of spirits >. Great depression of spirits, with a strong inclination to weep. Great despondency on account of the disease, is sure he is going to die in 24 hours. Has no fear of death but is sure he is going to die. Loss of memory ; listlessness, disinclination for bodily or mental exertion. Loss of memory, could not remember from one paragraph to another what she had read. Profound melancholy. Vacillation of mind. Head (Lac Vaccinum Defloratum) II General sore pain of head produced by coughing. II Intense pain at point of exit of supra-orbital nerve, diffused thence over forehead ; attack commences with chill, quickened pulse, flushed face and belching of wind from stomach (cured). II Throbbing frontal headache (over eyes), nausea, vomiting and obstinate constipation ; esp. in anemic women. I After injury subject to distress in head ; severe pain in forehead just above eyes ; breath very offensive ; appetite poor, nausea ; at times sleeps for hours during attack ; great distress across back ; urine dark and thick. I After light breakfast, pain in forehead, with nausea ; very pale face, even lips looked white ; vomiting of ingesta and afterwards of mucus and bitter water ; deathly sick feeling in pit of stomach, < rising up in bed ; profuse urination every half hour ; urine colorless as water ; great thirst ; intense throbbing pain in vertex. I American sick headache, with gastric symptoms. I At first a sharp pain at apex of heart, as though a knife was cutting up and down ; this lasts a few seconds and is followed by a strange feeling in head ; forehead feels extremely heavy, with dull sensation over eyes, and considerable throbbing, most marked on each side of head ; rest of head feels very light, dimness of vision ; can only distinguish light, not objects ; at same time great loss of strength ; cannot stand, but falls backwards, and remains entirely unconscious for two or three minutes ; weakness passes off gradually and is followed by crying, palpitation of heart and great depression of spirits ; imagines that all her friends will soon die and that she must go to a convent ; she can produce an attack at any time by extending arms high above head, or by pressure around waist ; spells come on at 7:30 P. M. I Attacks come every eight days ; during attack can neither eat nor drink, nor endure light or noise ; does not even like to speak ; great prostration, < during menstruation ; when pains subside inflammation of tonsils appears ; tongue white and no relish for food. I Dim vision, as of cloud before eyes ; profuse urination ; full feeling in head ; slight nausea at pit of stomach ; face pale ; feet cold ; coldness in back. I Faintness and nausea when stepping upon floor in morning. I General sore pain of head produced by coughing. I In morning nausea and sensation of a round ball full of pain in centre of forehead (cured). I Intense headache in forehead and through head ; < in vertex, afterward head felt bruised (cured). I Nausea and sometimes vomiting, which > ; pain in forehead as if head would burst, with blindness ; pain is > by bandaging head tightly ; < by light and noise ; constipation, stools large ; hands and feet cold. I Pain commencing in and above inner end of r. eyebrow before rising in morning ; soon after rising pain passed into eyeball ; < until afternoon, at which time it became unbearable ; < by walking and particularly by sitting down, though done carefully, also by heat radiated from fire or stooping, on pressure ; pressure on temples disclosed strong pulsation of artery ; pain ceased entirely at sunset and did not return till next day. Light did not < it. The eye had no unusual appearance. Lac Fel. had no effect. Partial relief by Sol. and Oxygen (cured by Lac Defloratum cm.). I Pain first in forehead, extending through occiput, making her nearly frantic. I Pain first in forehead, then extending to occiput, very intense, distracting and unbearable ; great photophobia, even to light of candle ; deathly sickness all over, with nausea and vomiting, < by movement or sitting up : very chilly, and external heat does not > ; frequent and profuse urination of very pale urine. I Pains so severe that she would bury her eyes in her hands and press them into pillow. I Periodical pain in forehead, as if head would burst, accompanied by violent effort to vomit, and more rarely vomiting ; hands and feet cold ; diarrhea alternating with constipation, the latter predominating ; loss of appetite ; smell or thought of food causes nausea ; tongue moist, coated white ; thirstlessness ; always < at menstrual period ; menses scanty and accompanied with colic. I Severe frontal headache ; nausea and sometimes vomiting upon rising in morning, or from recumbent position at any time, or upon moving ; great constipation ; constant chilliness even when near fire ; urine profuse and watery, or scanty and high colored ; intense pain throughout whole spinal column ; excessive thirst for large quantities ; great depression of spirits ; sudden prostration of strength at 5 P. M. ; skin color of red rose, with swelling of face, neck, arms and body, generally in morning and during day and evening. I Severe headache for years ; severe pain over eyes ; intense throbbing in temples. I Severe headache, with a sensation as if top of head was lifted off, raised about five inches and brains were coming out ; head feels hot, motion < pain ; face felt as if flesh was off bones and their edges were separated and sticking out ; better in five minutes after taking Lac Defloratum, and next morning was entirely relieved. I Severe pain over eyes, with intense throbbing in both temples, eyes feel as if full of little stones ; eyeballs intensely painful, and on shutting eyes, pressure of lids increases pain ; edges of lids feel contracted, and convey sensation as of a narrow band drawn tightly across eyeball ; pain over left hip ; constipation and profuse urination during paroxysm. I Throbbing in temples. I Vertigo : on moving head from pillow ; < lying down and esp. turning while lying, obliging to sit up. Bruised sensation in head caused by coughing. Burning in the top of the head. Dull, heavy pain all over temples and forehead and extending to occiput. During the headache, feet and hands cold. Flashes of heat in head and face. Forehead feels extremely heavy. Head feels large as if growing externally (cured).