Generals: Among the striking features of Opium is a class of complaints marked by painlessness, inactivity, and torpor. Many of the provers taking small doses had torpor, inability to realize or feel their surroundings, or to take in the nature of states and judge of things. Deception in vision, taste, touch; deception of the state he exists in; in his own realization; a perversion of all the senses with much deception. The general characteristic is painlessness, but now and then an alternate state is produced, in which a small dose of Opium will cause pain, sleeplessness, inquietude, nervous excitability; the very opposite state from that produced in the majority of cases. The majority are constipated, but in some there is dysentery and tenesmus. The patient is sleepy, yet at times the drug is characterized by sleepless nights, anxiety, increased sensitiveness to noise, so that he says ho can almost hear the flies walking on the wall, and hears the clock striking in the distant steeple. It is generally supposed that in these opposite conditions one is primary and the other is secondary. This is true, e. g., those exhibiting stupor and painlessness will go into a state of increased insensibility, inquietude, anxiety, and irritability, and also one who has a state of increased sensibility first will have a docile state following. Head and mind: Some oversensitive provers will get a basilar headache in the first hour after taking a dose, so that they cannot raise the head from the pillow; they are paralyzed from it; the pain holds them down. This does not come on in most provers until the waning of a large dose. This has been debated over as the primary and secondary actions. What is the action in one is the reaction in another, but all are the effects of the drug, and all the actions that follow are the symptoms of the remedy. The sluggishness and painlessness are most striking. The inaction is shown in the lack of reaction to the properly selected homeopathic remedy. It here competes with Sulphur. On studying the case you may find many Opium symptoms, and when given thus indicated, it rouses the system out of the state of sluggishness and causes reaction. Ulcers which are perfectly painless, which do not granulate, and do not eat or spread, with numbness or lack of sensibility in the ulcer that ought to be sensitive; Opium will often heal insensibility in parts that are in a high grade of inflammation. Paralytic conditions or paresis, partial paralysis; inactivity, sluggishness. Such a condition is found in the bowels so that they do not move, and rectum fills with round, hard, black balls, which can be dug out with the finger or spoon. There is no activity, no ability to strain at stool. The bladder is in a similar state. There is no ability to use the abdominal muscles; he cannot strain to urinate retention of accelerator muscles are in a state of paresis. When drinking the oesophagus seems to have no action and the fluid does not go down but passes out through the nose; a paresis fluids go down the wrong way or out through the nose. Weakness of limbs and muscles; weakness and paralysis. Often there is a state of peace. Wants to be let alone. She tells you she is not sick; and yet she has a temperature of 105-106°, is covered with a scorching hot sweat, has a rapid pulse; is delirious. You ask her how she is and she says she is perfectly well and happy; no pains or aches; wants nothing and has no symptoms. But the nurse tells you that the patient has passed no stool or urine.