The genus Prinos is very closely, allied to the hollies. "The bark of P. vertic. is bitter, and has been used in the treatment of fever, and in the form of a lotion as an application in cases of gangrene. The berries are tonic and emetic "(Treas. of Bot.). The only recorded experiment with Pri. v., the effects of swallowing twenty berries, bears out the last statement: the effect was to cause vomiting (and also an extremely profuse greenish diarrhoea); increased appetite and tense feeling of well-being in spite of great loss of weight.