An interesting flower, in woods, Canada and United States, ap- pearing in early spring. Rhizome fleshy, tuberous, and when broken or bruised exudes an orange-red fluid, as also does every other part of the plant. From each bud of the root-stalk there springs a large, single, glaucous leaf, and a scape about six inches high, with a single flower. Whole plant glabrous. Leaf kidney-shaped, with roundish lobes separated by rounded sinuses. Flowers of a quadrangular out- line, white, scentless and of short duration. April and May. (Wood. ) Dr. Downey swallowed twenty grains of the root, and eight of the extract. These doses caused : nausea and vomiting, warmth and heat in the stomach, quick pulse, headache. The root irritates the fauces and causes diarrhoea. The seeds occasion : torpor, languor, disordered vision and dilatation of the pupils. Large doses cause : violent vomiting, burning in the stomach, faintness, vertigo, alarm- ing prostration. In overdoses it causes extreme reduction of the frequency and of the force of the pulse-beat, irregular action and palpitation of the heart, and sometimes convulsive rigidity of the limbs. CEPHALIC GROUP. Sanguinaria has caused a large variety of head symptoms ; among them we have : Long-continued, severe vertigo ; vertigo, brought on by rising quickly from a stooping position, or by turning the head quickly. Dull, heavy ache, and ache and pressure in the temples. Determination of blood to the head, with whizzing in the ears and transitory feeling of heat; then a sensation as if vomiting were to take place, but instead of this, there was some cutting drawing pain in the abdomen, and then some stool. The head aches as if it would burst; it is better when walking in the open air; the pain is especially in the right temple. Throbbing headache, with bitter vomiting. Dizzy, severe headache, extending to the right temple ; tearing pain ; sensation as if a nail were being driven into the brain. Sharp, severe frontal headache, with nausea, especially upon moving. Pains like an electric shock in the forehead. A band-like constric- tion across the forehead, just above the eyebrows, in the afternoon. Pain and fulness in the vertex. Soreness of the scalp on touch.