Acts chiefly on the genito-urinary organs, affecting especially the prostatic portion of the urethral mucous membrane, causing irritation and chronic inflammation, sometimes extending into the ejaculatory canals and seminal ducts, often presenting in its symptoms a picture of spermatorrhoea, in which disease it has proved of great value. Staphisagria affects also the cerebrum, the digestive tract, and the skin, as shown by its pathogenesis. Characteristic symptoms.