Acts especially on the ganglionic nervous system, affecting primarily the venous capillary system, and through it affecting profoundly the entire vegetative sphere, penetrating deeply every recess of the human body. Precisely how this mighty agent operates, and exactly the channels through which it produces its wonderful changes in organic and functional life, may not be definitely known, yet the effects of these operations are ever before us, and offer conclusive evidence as to the character of the remedy, in its general constitutional action, tainting the system, as it does, with a chronic miasma, peculiar to itself, yet simulating a vast array of pathological states which have, for their peculiar expression, some character of cutaneous eruption. Thus, as we have indicated, the chief local action of Sulphur is found to be upon the skin, producing various forms of eruption, papular, vesicular, pustular, and herpetic, its most noted action being an itching, vesicular formation, holding a marked resemblance to scabies or itch, and other kindred affections of the skin. Sulphur also affects particularly the lymphatic glandular system, the mucous membranes, especially of the eyes, bronchi, urethra, and rectum, and the portal system, especially the haemorrhoidal vessels. Characteristic symptoms.