Pains from darkness to daylight; begins with twilight and ends with daylight (Merc, Phyt.). Pains increase and decrease gradually (Stan.); shifting and require frequent change of position. All symptoms are worse at night (Merc); from sundown to sunrise. Eruptions: dull, red, copper-colored spots, becoming blue when getting cold. Extreme emaciation of entire body (Abrot., lod.). Heart: lancinating pains from base to apex, at night (from apex to base, Med.); from base to clavicle, or shoulder, (Spig.). Loss of memory: cannot remember names of books, per- sons or places; arithmetical calculations diificult. Sensations: as if going insane; as if about to be paralyzed; of apathy and indifference. Terrible dread of night on account of mental and physical exhaustion on awakening; it is intolerable, death is preferable. Fears the terrible suffering from exhaustion on awakening (Lach.). Leucorrhea: profuse, soaking through the napkins and run- ning down to the heels (Alum.). Headache, neuralgic in character, causing sleeplessness and delirium at night; commencing at 4 p. m.; worse from 10 to 11 and ceasing at daylight (ceases at 11 or 12 p. m.. Lye); fall- ing of the hair. Acute ophthalmia neonatorum; lids swollen, adhere during sleep; pain intense at night < from 2 to 5 A. m. ; pus profuse; > by cold bathing. Ptosis: paralysis of superior oblique; sleepy look from drooping lids (Caust., Graph.). Diplopia, one image seen below the other. Teeth: decay at edge of gum and break off; are cupped, edges serrated; dwarfed in size, converge at their tips (Staph.). SYPHILINUM. 473 Craving alcohol, in any form. Hereditary tendency to alcoholism (Sar., Psor., Tuber., Sulph., Sulph. ac). Obstinate constipation for years; rectum seems tied up with strictures; when enemata were used the agony of passage was like labor (Lac d.. Tub.). Fissures in anus and rectum (Thuja); prolapse of rectum; obstinate cases with a syphilitic history. Rheumatism of the shoulder joint, or at insertion of deltoid, < from raising arm laterally (Rhus — r. shoulder. Sang. ; left, Fer.). When the best selected remedy fails to relieve or perma- nently improve in syphilitic affections. Syphilitics, or patients who have had chancre treated by local means, and as a result have suffered from throat and skin troubles for years, are nearly always benefited by this remedy at commencement of treatment unless some other remedy is clearly indicated. Relations: antidote; Nux vomica, for over-action or excess of action in sensitive organizations, or too frequent repetition of the remedy, especially in the higher potencies.