A perfect picture of collapse, with extreme coldness, blueness, and weakness, is offered by this drug. Post-operative shock with cold sweat on forehead, pale face, rapid, feeble pulse. Cold perspiration on the forehead, with nearly all complaints. Vomiting, purging, and cramps in extremities. The profuse, violent retching and vomiting is most characteristic. Surgical shock. Excessive dryness of all mucous surfaces. "Coprophagia" violent mania alternates with silence and refusal to talk.