Introduced by Hering, Amerikanische Arzneipriifungen (see Bienengifte). There are no provings with the exception of those by Berridge of Vespa crabro, the hornet, 30th dilution, Med. Inv., vol. 1, New Ser., 1875, p. 100. The symptoms quoted are mainly the results of the sting. Authorities : See Allen's Encyclopedia, vol. 10, pp. 119 and 639. Clinical Authorities. — (Edema nf face, etc., Blake, Org., vol. 1, p. 320, from Horn. Eev., vol. 22, p. 270 ; Ophthalmia (Vespa crabro),, Berridge, Org., vol. 2, p. 318 ; Vesical catarrh, Hering, MSS. ^ Mind. Insensibility; loss of consciousness; inability to move. Anxiety and universal distress. Low-spirited. ^ Sensorinm. Fainting, loses consciousness. A violent heat came over him, felt sick; then turned giddy and spun round and round like a top till he fell head- long into a currant bush ; managed to stagger like a drunken man to house, got into chair, in a moment fell out of it upon his knees, all but fainting ; dashed water YESPA. 452 into his face, at length he was able to lie down upon his bed. ^ Inner Head. Headache. * Outer Head. Face swollen and inflamed ;. swelling extends upward over head. Alopecia. ^ Sight and Eyes, Vision, especially r. eye, growing dim. Eyes turned red and twitched. Swelling and puffiness of lower lids. Eyes nearly closed, two or three hours after sting. Injection of conjunctiva of r. eye. Itching of eyelids ; adhesion in morning. Itching and redness in eyes. . Itching of r. lid in evening, slight tumefaction ; lids more swollen and painful ; swelling increased, considerable pain in eyeball and lids all night; lids, greatly tume- fied with what seemed to be erysipelatous inflammation; whole side of face painful and swollen; on opening lids discovered almost complete chemosis of conjunctiva, it being raised up on sclerotic membrane more than half over eye to border of cornea, as if fatty matter were underneath it, caused by effusion of lymph; an abscess opened upon inside of upper lid about its centre ; swell- ing began to abate and chemosis to flatten down, assum- ing instead of a semi-transparent, a reddish hue, as in common ophthalmia; discharge from abscess piofuse; in fourteen days chemosis entirely disappeared. I I Right eye inflamed for six days; it had commenced with lachrymation; had taken Aeon, without relief; now there is redness of conjunctiva of r. lower lid ; in 1. lower half of r. eye is a semi-transparent baggy swelling of con- junctiva extending up to cornea, and on pressing it up- ward it partly covers cornea; much lachrj'mation of r. eye, < in open air, r. eyelids adhere in morning; man, set. 60. ^ Hearing and Ears. Subdued, stitchlike pain deep in r. ear. ^ Upper Face. Face: anxious; livid; bluish; smooth, dark- red and bloated. Facial neuralgia. An ulcer lasting three months after a sting in cheek. Stings in face, swelling closing eyes. Swelling and redness of face like erysipelas. After a sting in cheek a violent sensation burning like fire, as if it were going deep in ; a sensation followed as if something were sticking deep in, like a harpoon, and were drawn on frequently ; place of sting bright-red, ele- vated, and a hard swelling followed ; there was a very marked chilly-cold sensation all around red middle and this was followed by a general chill. 453 VESPA. Face and ears became red as if covered with scarlet rash. Face, especially eyelids, swollen and puflfy. I iFace swollen and puffy; skin transparent and etiolated; scalding nrine, followed by itching; itching of r. arm ; vision, especially of r. eye, growing slowly dim ; palpi- tation on exertion ; flatulence. Next day, about 4 a.m., I was suddenly awakened by a- burning, stinging sensation in cheek, and a great soreness and smarting along course of lymphatics down into neck; I found my cheek much swollen and red, and there was a patch of redness about size of a florin that felt as if it were being pierced with red-hot needles; temporo-maxillary joint stiff and painful, and a feeling of soreness ran along gums to tonsils on that side of face ; after bathing for a while affected parts, I got into bed again, feeling somewhat >, and fell asleep again; about two liours afterward I was again suddenly aroused, this time by a sense of suffocation and difficulty of swal- lowing with renewal of former distress with intensified severity; feeling alarmed, I obtained some hot water, to which I added a few drops of tincture of Ledum and fomented whole of affected part until severity of symp- toms abated; during remainer of that day and for four days afterward attacks continued to r.eturn in parox- ysms of more or less severity ; submaxillary and cervi- cal glands on that side of face became increasingly swollen and tender until fourth day, when these condi- tions began gradually to abate ; in immediate locality'' of wound pains began to assume a more constant char- acter, throbbing, smarting and burning ; still there'was a marked periodicity about stinging and lancinating pains experienced for more than a month afterward, although wound suppurated and discharged freely; gen- eral constitutional disturbances were marked b}^ slight rigors and febrile conditions felt mostly in evening. '" Teeth and Gums. Quaked and trembled ; teeth chattered as if he had a paroxysm of ague. ^^ Taste and Tongue. Pain for a minute or two intense, fol- lowed by a peculiar taste, a singular combination of palatal and nasal sensation, such as is noticed when a nest of these wasps is disturbed and they dart about through air; for a week constant and annoying, then intermittent and very pungent, and whenever heated by exercise or near a hot fire. Swelling of tongue, could scarcely talk ; pain exceedingly violent, burning stinging (Apis 30 relieved). Tongue very red, greatl}^ swollen and rounded ; could not move it about or protrude it, it appeared to entirely fill VESPA. 454 mouth ; could not speak, only mumble, swallowing pain- ful and difficult. Tongue very much swollen and tense; considerable swell- ing immediately below chin, between that and hyoid bone; pain referred to a point in middle line of tongue about three-quarters of an inch from apex. Found her in a state of terrible anxiety, with eyes and face oedematous, and quite unable to articulate or to protrude her tongue, but she could open her mouth a little and I could see sting embedded in middle third of tongue ; I at once extracted it ; tongue itself with its root and whole floor of mouth swelled so that cavity of mouth was entirely filled therewith and then nothing else could be seen ; she could not articulate a single word ; suffered great pain in tongue, which she described afterward as burning, throbbing and aching ; great anxiety, appearance of face, mouth and throat that of severe cynanche ; great dysphagia ; surface of tongue and lining of cavity of mouth did not seem especially red, swelling being diffused and deep-seated. ^^ Inner Mouth. Sting on roof of mouth caused immediately swelling in mouth and throat; burning pain ; nausea and vertigo ; two hours afterward violent fever, pulse 126 per minute ; loss of consciousness, delirium ; face, neck, arms and chest swollen and red and glistening; breathing oppressed ; swallowing very difficult. (Spir- its of Camphor relieved ) ^2 Throat. Sore throat. Sensation of heat in throat. Throat greatly swelled. Dangerous swelling in oesophagus. Erythema spread into mouth and down into stomach, causing vomiting with temporary relief. Tonsils repeatedly inflamed. Pharyngeal varicosis. Hypertrophied tonsils secreted a cheesy matter. Swelling of mouth and throat with violent burning pains, nausea and vertigo so that patient was obliged to go to bed ; after two hours a violent fever, unconscious and delirious, face, neck and arms swollen and shining red; respiration impeded, swallowing very difficult; pulse 126 ; heart's action irregular and tumultuous. (Cured by Camphor.) '' Eating and Drinking. Indigestion with flushing after meals. '•^Hiccough, Belching, Nausea and Vomiting. Eructa- tions. Nausea, with faint feeling and trembling. Vomiting. 455 VESPA. *^ Scrobiculum and Stomach. Weight in stomach with nausea. Heat or cold feeling in stomach. ^^ Abdomen. Uneasiness in bowels. Restlessness in abdomen.