1 . Dark, spare withered-looking subjects ; disposition gen. mild and cheerful. 2 . Attacks of depression. Loss of memory ; time passes slowly. 3 . Great dryness of all mucous membranes (except female genitalia) with sense of constriction. 4 . Abnormal appetite, craving for indigestible things ; potatoes disagree. 5 . Inactivity of the rectum ; no desire and no ability until large accumulation, even soft stool requires great straining ; stool hard and knotty or soft, clayey and adhesive, 6 . Leucorrhoea, acrid , transparent, profuse, running down to the heels (Syph.) < daytime ; gen. assoc. delayed, scanty menses after which patient physically and mentally exhausted. 7 . Paralytic weakness of lower limbs with great heaviness and lack of co-ordination ; "must sit down" ; also with burning pain especially in the back. 8 . Chronic throat conditions, "every cold settles in the throat". 9 . Skin eruptions < winter ; intolerable itching < warmth of bed ; < starchy foods and all irritating things (salt, pepper, etc.). 10 . Modalities. Patient chilly < cold except headache ; at new and full moon ; on alternate days ; > eating. Notes. A chronic of Bryonia . Slow but long-acting chronic remedy.