Peculiarities about the rectum and stool afford hints to the use of this remedy. For instance, when there is inactivity of the rectum, requiring great straining to evacuate even a soft stool. No desire to stool for days, sometimes a week, until there is a large accumulation, and then evacuation seems only after great effort. Even if the accumulated stool be very soft, the same effort is required to pass it. One must strain at stool in order to urinate. We see this in dysentery, typhus, and in many other disorders, when Alumina will be very likely the remedy. Mental.-- Confusion of intellect, loss of memory, time passes too slowly. Seeing knives or scissors she is seized with desire for suicide. Sad thoughts constantly crowd upon the mind; everything is viewed in a sad light. Very changeable mood the same day, alternating from vivacity to thoughtfulness, full of assurance, great timidity. Fears of losing the reason. All mental symptoms worse on waking in the morning. Has a sensation as if he would fall forwards, which he greatly fears.