Who first proved this remedy ? Hahnemann. Its pathogenesis is in the Materia Medica Pura . What is Cina, where is it found and what is its alkaloid ? It is the Artemesia cina , an aromatic plant growing in Europe and Asia. Our tincture is made from the flowers, which are dried, powdered and treated as described under Staphisagria ; its alkaloid is called Santonine , and it is poisonous. What is the general action of Cina and its alkaloid Santonine ? It is principally a children's remedy, corresponding to many conditions that may be referred to intestinal irritation, such as worms, etc. What are the symptoms calling for Cina in worm affections ? Sickly, pale face, with rings around the eyes ; gritting of the teeth at night ; canine hunger, or variable appetite ; the child picks its nose and cries out in its sleep ; jerking of hands and feet ; urine milky. What are the mental symptoms of Cina ? Children awake in a fright, scream, tremble and cannot be quieted ; they are proof against all caresses ; are cross, irritable, nervous and peevish ; they want to be rocked.