Sensitiveness: This drug is characterized by a general sensitivity. Sensitiveness of vision, of hearing, of smell, of touch; sensitiveness to pain. it is most astonishing sometimes about this great sensitiveness. Pains are increased by noise. Sensitiveness of hearing is so great that sounds are painful. Pains in the face, toothache, headache; pains in the lower limbs; everywhere aggravated by noise. All the nervous disturbances possible are found in this medicine, and they are all aggravated by noise. Even the opening of the door and the ringing of the door-bell produces great suffering. Such patients are so sensitive that they hear sounds which those in a state of health cannot hear. Perhaps no medicine in the Materia Medica approximates this sensitiveness of hearing where it is accompanied with pain, unless it be Nux vom. Those practitioners who do not know this generally resort to Nux vom. for pains aggravated from voices in another room, or from noise or the sound of children. Many remedies have increase of nervousness from noise; noise aggravates headache, and aggravates suffering about the head, and makes some persons nervous, But pain in the extremities aggravated by noise is peculiar. It seems that the noise disturbs him so that he cannot bear pain. The Coffea state is brought on by emotions or violent excitement of the mind, but especially by joy or "pleasant surprise." The result is sleeplessness, nervous excitement, neuralgia, twitching of muscles, toothache, face ache, red face and hot head. You may be called to the bedside of a woman who has been laboring for some great cause. She works persistently, is successful, but goes to bed with weeping, delirium, neuralgia, sleeplessness. Her heart palpitates, her pulse flickers, she has fainting spells, and without Coffea she may die. Coffee drinkers who keep up through some ordeal and then break down are similarly affected. The Coffea patient is sensitive to wine. A small amount of wine intensifies the nervousness, produces sleeplessness, flushed face, feverishness, great excitement. Not necessarily intoxication, but nervous excitement. Coffea has a painful sensitiveness of the skin beyond comprehension. I remember one particular case. A woman bad her lower limb out of bed and it was as red as fire down one side. I walked toward it to put my hand on it. But she said, "Oh, don't touch it, I can't bear to have it touched; I can't touch it myself." I asked how long this had been coming on. She said, "Ob, it all came on within an hour." Such a symptom is common in coffee drinkers. There was no fever. Intense stinging, burning pains in the skin with the redness and heat with coarse rash coming on suddenly, leaving just as suddenly. The sensitive part is aggravated by cold air, aggravated by any wind or from fanning, from motion, yet aggravated by warmth. Aggravated from anyone walking across the floor. The woman I referred to scowled when I was walking toward the bed. A number of times I have seen such things relieved within a few minutes by Coffea.