Authority. E. W. Berridge, M.D., U. S. Med. Invest., New Ser., vol. iv, 1876, p. 574, Mr --- took 15 grains in one dose. Uninterrupted sensation, as if an immense load were on entire upper portion of head, causing a gloomy apprehensiveness of congestive apoplexy. It lasted two or three days, and was removed by a dose of Nux 1 (after two days). Heat from, or heat at cardiac orifice of stomach, lasting twelve hours; not affected by food or drink (after two hours).