Great relaxation, not only physical, but mental, after slightest effort. Tremblings, especially in the evening, < tobacco smoking. Limbs feel weak and bruised in the morning. Pain, as if the flesh were loosened from the bones, especially in the thighs and upper limbs, on motion. Sensitiveness to air ; takes cold easily, dreads open air. Pulsation throughout the whole body, even during rest, < the slightest motion. Weakness when standing, with a feeling of heaviness of the feet, especially after walking, or after eating. Pains at night take away the breath and seem almost to cause paralysis. Greatest weakness in the morning in bed.