1 . Cachectic, anaemic subjects ; pale, earthy or yellowish. greasy-looking complexion ; children emaciated (especially about the neck) and old in appearance ; debility from loss of vital fluids. 2 . Great depression ; lachrymose yet irritable especially at small, non-essential noises ; seems to desire but is markedly < consolation ; dislikes company, > alone ; emotionally sensitive to music memory weak with inability to concentrate ; hysteria, affections beyond control. 3 . Headaches , chronic, hammering, periodic, blinding ; from sunrise to sunset , < motion > semi-recumbent position, face pale or only slightly diffused ; especially in anaemic girls and women. 4 . Condition of mucous membranes :-(a) Chronic ; dryness with ulcerations or cracks ; e.g. of alimentary canal with constipation. dry, crumbling stools, and sore. fissured anus ; (b) acute ; free watery discharges , often coarse, frothy mucus especially from upper respiratory tract. 5 . Good appetite yet emaciation ; inordinate craning for salt (Phos.) dislike to fats and bread ; > going without regular meals. 6 . " Mapped" tongue ( patchy appearance) with sense of dryness and violent thirst. 7 . Skin ; (a) chronic ; dryness with fissures, corns, warts, hangnails, etc., (b) acute ; eczematous. eruptions, raw surface, acrid, watery discharge, especially at scalp margin ; acne ; urticaria after violent exercise ; hydroa on lips or tongue, especially during colds or intermittents. 8 . Backache ; severe, sacro-lumbar ; > pressure, e.g. lying on something hard ; often assoc. with delayed menstrual period and bearing-down pains. 9 . Inability to micturate in the presence of others. 10 . Modalities ; < heat especially close room, must have air though apt to feel chilly and take cold ; < 9 - 11 a.m. ; salt ; at seaside, etc. ; mental exertion ; > loose clothing. Notes : Chronic of Ignatia and Bryonia . Should not be given during a fever paroxysm.