Acts specially on the portal system, with venous congestion. Stasis and thereby ptosis of viscera and weariness and misery. Weakness, yellow complexion, bearing-down sensation, especially in women, upon whose organism it has most pronounced effect. Pains extend down to back, chills easily. Tendency to abortion. Hot flashes at menopause with weakness and perspiration. Upward tendency of its symptoms. Easy fainting. "Ball" sensation in inner parts. Sepia acts best on brunettes. All pains are from below up. One of the most important uterine remedies. Tubercular patients with chronic hepatic troubles and uterine reflexes. Feels cold even in warm room. Pulsating headache in cerebellum.