Metallic copper is an antipsoric remedy, working from within outwards. It ranks with the most important of those which relieve states arising from the "striking inward" of diseases or the failure of eruptions or discharges to appear. It is this power to relieve internal spasm which renders it appropriate to the collapse stage of cholera, of which it is also, like Sulphur, a prophylactic either when worn next the skin, or when taken internally. Cuprum produces many skin eruptions, and also foot-sweat, and it corresponds to these, and also to the effects of suppression of eruptions, exanthems, and foot-sweat; whether these effects be internal pains or spasms or oppression of the brain and mental disturbance. Mackechnie made a brilliant cure of psoriasis in a young girl with Cuprum. The leading features of its symptomatology are: Cramps, convulsions, spasms of the most violent form, coming on from disappearance of pains, discharges, eruptions, mental derangement. With suppression of menses, patient screams. Tonic spasms of thumbs. Eyeballs turn up. Opisthotonos. Tonic and clonic spasms. "Convulsions during pregnancy and puerperal convulsions which begin in the fingers or toes, and spread all over the body; or where there is great restlessness between the attacks, either filling up the entire interval, or only a part of the time." Thus Guernsey. He also says that "a slimy metallic taste in the mouth" is one of the strongest indications for Cupr. Rhus is the only other remedy which has this symptom so marked. "Cramps or spasms beginning in hands and feet, extending to belly," is confirmed by J. C. McLaren. Mossa regards Cupr. as one of the remedies for the effects of fright, and relates the case of a girl who, after a fright, was affected by involuntary motions of left arm and leg developing into pronounced general chorea. Cupr. brought about slow but decided recovery. Another girl, 12, who had recovered from whooping-cough got a kind of chorea from repeated frights on seeing an epileptic. To the muscular movements was added silly behaviour: tongue heavy, speech slow, gait unwieldy. Frightened at night. Greediness in eating and drinking. Ign., Stram., Sul., did little good. She became ill-natured. Cupr. every four days cured completely in three months. Mackechnie reports the case of a boy who became epileptic after being locked up in school. Very great improvement followed the administration of Cupr. Schwencke cured a case of epilepsy of forty years' standing with Cupr. 6 after Bell. and Hyo. had done some little good. The patient was a man aged 45. The fits began suddenly towards morning with chewing motion of lower jaw; gnashing of teeth; becomes upright and rigid in bed; shrieks; limbs convulsed. After giving way to violent anger, attacks become more severe; arms and legs were thrown outwards and trunk arched upwards. Cupr. was now given. For a time the attacks continued severe, but gradually improvement set in, and in less than three months they ceased altogether. The "anger" in this case and the "ill-humour" in Mossa's are noteworthy. Maliciousness is an indication for Cupr. In a second case cured by Schwencke, that of a man, 38, epileptic seven years, a pressive headache preceded the attacks, ascending from nape to forehead; then there was profuse salivation, head turned to left, eyes closed, tongue in active motion in open mouth, trunk arched upward, slight spasms of right arm outward. After attack, dulness of head, and feeling in body as if beaten. Cupr. first removed the fits and then the dulness of the head. Cupr. has pains like knife-thrusts, < on least motion; take away the breath, thinks he must die if they last. Speaks in a whisper. The thrusts go through to back from ensiform cartilage, from umbilicus. Restless tossing all night. Perfect stupor, with jerking of muscles. Paralysis of isolated muscles. Many unusual symptoms are produced, including maliciousness and desire to injure. Screaming, with cerebral or mental symptoms. Loquacious. Violent head pains < over left eye. Brain seems paralysed. Chlorosis from abuse of iron. Vomiting, hiccoughs, and spasms > by drink of cold water. Over-sensitiveness of skin, especially in region of stomach and fourth and fifth dorsal vertebrae. Touch and pressure <. < Before menses; from vomiting. Symptoms are < evening and night. Cold air and cold wind <; cold drinks > (colic, cough &c.). Wrapping head > headache. < At new moon. Periodicity every 15, 30, or 60 minutes; every fortnight. Getting wet = epileptic attacks. > From being mesmerised; during perspiration. Suited to fair-haired people; and the carbo-nitrogenoid constitution. Women who have borne many children (after-pains).