The singularly contradictory character of Ignatia, both mental and physical, gives an insight into its sphere of usefulness in whatever condition. The pains are acute and excruciating in character ; the aggravations and ameliorations are peculiar and marked ; and when taken in connection with the concomitant symptoms point unmistakably to its selection. Use Pulsatilla to antidote Ignatia rather than Nux vomica, for the latter may prove inimical.