The first trituration, and first dilution in alcohol, of the snake poison, Trio-o- nocephalus Lachesis, was made by Hering, on July 28th, 1828. The first cases were published in the Archives, in 1835. In 1837 this remedy was introduced into our Materia Medica. See Effects of Snake Poison, by C. Hering, Denkschriften der Nordamerikanischen Akademie der homoopathischen Heil- kunst, Allentown, Pa. Provings by Hering, and under his direction by Stapf, Bute, Bauer, Behlert, Detwiller, Gross, • Kummer, Eeichhelm, Roenig, Wesselhoeft, Kehr, Koth, Mat- lack, De Young, Helfrich, Schmoele, and Lingen. Later proving-s were made by Eobinson, Fellows (Fincke, not contained in Encyclopedia), Bartlett, Metcalf and Berridge. See Allen's Encyclopedia, vol. 5, p. 432. Clinical Authorities.— i/fmtaca^ jealousy, Woost, Ruck.- Kl. Erf., vol. 5 p. 6 ; Delirium Iremem, Hering, Riick. Kl. Erf., vol. 1, p. 143; Melancholy, Guernsey,' Raue's Rec, 1871, p. 49 ; Melancholia after confinement, MSS. ; Mental disorder, Berridge, Raue's Rec, 1872, p. 51; Horn. Clin., vol. 4, p. 73; Wesselhoeft, Raue's Rec, 1871, p. 47; Smith, N. E. M. G., vol. 8, p. 314; Weber, Med. Inv., vol. 5, p. 34; Gross, Riick. Kl. Erf, vol. 1, p. 32; Irritation of meninges of brain and spinal cord. Pope, B. J. H., vol. 13, p. 479 ; Brain irritation, Nankivell, A. H. Rev., vol. 13, p. 360 ; Inflammation of brain, Lunzer, Riick. Kl. Erf., vol. 5, p. 44 ; Sunstroke, C. B. Knerr, MSS.; Affection of brain. Miller, H(.m. Clin., vol. 3, p. 97; Encephaloma, Jackson, Gilchrist's Surgery, p. 161, N. A. J.H., vol. 22, p. 363; Vertigo, J. C. Cummings,MSS.; Headache (4 cases), Neidhard, MSS.; C. H.Vilas, MSS.; Wesselhoeft, B. J. H., vol. 22, p. 483; Sawyer, Am. Horn. Obs., vol. 2, p. 138 ; Pope, B.J. H., vol. 13, p. 478 ; Megrim, Tietze, Peters, Pope, Ruck. Kl. Erf., vol. 5, p. 89 ; Cephalalgia, Raue's Rec, 187(»| p. 287; Supraorbital neuralgia, Martin, Med. Inves., vol. 7, p. 594; Asthenopia, Norton's Ophth. Therap., p. 109; Defective sight after diphtheria, MSS.; Post-diph- theritic eye affection, Martin, Org., vol. 2, p. 108 ; Retinitis apoplectica, Norton's Ophth. Therap., p. 109; Inflammation of eye, Rittenhouse, Trans. Horn. Med. Soc Pa., 1873, p. 106; Orbital cellulitis, Allen, Norton's Ophthal. Therap., p. 108; Pterygium, Rittenhouse, Trans. Horn. Med. Soc. Pa., 1873, p. 107; Partial deafness, Martin, Raue's Rec, 1872, p. 81 ; Affection of ear, Martin, Hom. Clin., vol. 4, 149 ; Lippe, Riick. Kl. Erf., vol. 5, p. 159 ; Epistaxis, J. S. Linsley, MSS. ; Coryza, MSS. ; Chronic nasal catcm-h, W. Story, MSS. ; Affections of nose, Rosenberg, Riick. Kl. Erf., vol. 5, p. 173; Neuralgia of fcx.e, Bnjanus, Raue's Rec, 1871, p. 179; Tietze, Note.— A circular letter issued by Dr. Hering, in 1878, soliciting contribu- tions of clinical matter, provings, etc, for a full collection of reports wherewith to celebrate the Fiftieth Anniversary of the introduction of Lachesis, was freely and generously responded to by numerous members of the profession, whose names ap- pear in the list of Clinical Authorities, followed, by the abbreviation MSS. The author did not live to finish his intended Monograph, but all that is essential and of guiding value in Lachesis is embodied in our arrangement. — Eds. LACHESIS. 560 Euck. Kl. Erf., vol. 1, p. 425 ; Swelling of face, Duncan, Horn. Clin., vol. 1, p. 24o ; Erysipelas of face, Berridge, Times Eetros., vol. 3, p, 30 ; Parotitis, Smith, Med. Inv., vol. 5, p. 106 ; Bleeding of gums, Leon, Eiick. Kl. Erf., vol. 4, p. 666 ; GLossomania, Gross B. J. H., vol. 12, p. 472 ; Sore mouth of nursing women, C. Pearson, MSS. ; Nursing sore mouth, Raymond, Med. Inv., vol, 5, p. 72 ; Affection of mouth after diphtheria, MSS.; Sore mouth and throat after scarlet fever, Preston, Pane's Pec, 1870, p. 321; Chronic irritability of fauces, Wessellioeft, B. J. H., vol. 22, p. 488; 2%-oat affection, C. Hering, B. J. H., vol. 21, }». 370; Affection of throat after diphtheria, MSS. ; Inflamnudion of throat, Paymond, Med. Inv., vol. 5, p. 72 ; Angina, Stow, Paue's Pec, 1870, p. 142 ; Berridge, Pane's Pec., 1870, p. 142 ; Fielitz, Jahr, RUck. Kl. Erf., vol. 1, p. 531; Sore throat, Blakely, Horn. Clin., vol. 1, p. 126; Boyce, Med. Inv., vol. 5, p. 6; (5 cases) Neidhard, MSS.; Tonsillitis, Hirschel, Piick. Kl. Erf., vol. 5, p. 242 ; Blakely, Raue's Pec, 1870, p. 141 ; Horn. Clin., vol. 1, p. 232; Epidemic pharyngitis (50 cases). Ward, Am. Hom. Obs., vol. 6, j). 226; Chronic pharyngitis. Miller, Raue's Pec, 1875, p. 246; Diphtheria, Guernsey, Oehme's Therap., p. 46; Allen, N. A. J. H., vol. 13, p. 99 ; Hale, Hom. Clin., vol. 1, p. 184; (3 cases) Hale, Oehme's Therap., p. 48 ; Goodno, Hom. Clin., vol. 3, p. 140 ; (2 cases) Goodno, Oehme's Therap., p. 49 ; (2 cases) Hirsch, Oehme's Therap., p. 46 ; (5 cases) Wesselhoeft, Oehme's Therap., pp. 47-48 ; Dunham, A. H. O., vol. 4, p. Ill ; Tietze, B. J. H., vol. 31, p. 124 ; Oehme, N. A. J. H., vol. 25, p. 68 ; T. S. Hoyne, MSS. ; A. M. Piersons, MSS. ; (3 cases) Piersons, Hah. Mo., vol. 10, p. 212; (8 cases) MSS.; Von Tunzelmann, Am. Hom. Rev., vol. 17, p. 741; C. W. Boyce, MSS.; Fellows, Am. Hom. Rev., vol. 5, p. 412; C. Pearson, MSS.; Rittenhouse, Paue's Pec, 1872, p. 103; Schmitt, Hom. Phys., vol. 4, p. 190; Beau- mont, Org., vol., 3, p. 93; Syphilitic phagedcena of fauces, Hale, Raue's Pec, 1874, p. 109 ; Spasmodic stricture of throat, Bartlett, Riick. Kl. Erf., vol. 5, p. 242 ; Foreign body in oesophagus, Herzberger, B. J. H., vol. 36, p. 376 ; Dyspepsia, Hering, Riick. Kl. Erf, vol. 1, p. 586; Affection of stomach, Neidhard, MSS.; Affection of liver, Luther, Ruck. Kl. Erf., vol. 5, p. 339 ; C. Neidhard, MSS.; Affection of spleen, C. Neid- hard, MSS. ; Typhlitis, Hering, Black, Piick. Kl. Erf., vol. 1, p. 725; Peritonitis, Wesselhoeft, B. J. H., vol. 22, p. 485 ; Burkner, Riick. Kl. Erf, vol. 5, p. 669 ; Tumor in I. groin, H. C. Bartlett, MSS. ; Buboes, Riick. Kl. Erf., vol. 5, p. 560 ; Diarrhoea, Gross, Riick. Kl. Erf., vol. 1, p. 837; C. Neidhard, MSS. ; Constipation, Hering, Riick. Kl. Erf., vol. 1, p. 816 ; Smith, N. A. J. H., vol. 14, p. 176 ; Croup- ous enteritis, Gerson, Riick. Kl. Erf., vol. 5, p. 420 ; Dysentery, Boyce, Paue's Pec, 1874, p. 174; Affection of anus and rectum, Morgan, Am. Hom. Rev., vol. 4, p. 409 ; Hemorrhoids, C. Neidhard,MSS.; Anal fistula, Eggert, Raue's Pec, 1 870, p. 219 ; Med. Inv., vol. 6, p. 143 ; Strangury, C. Neidhard, MSS. ; Ovaritis, Conant, Times Petros., vol. 1, p. 93; Sacculated ovarian disease, Baer, Org., vol. 3, p. 103; Ovarian tumor. Dudgeon, Gilchrist's Surgery, p. 161, B. J. H., 1873, p. 183; Uterine and ovarian f -(mors ; Metritis, J. C. Morgan, MSS. ; Chronic uterine catarrh, Lindsay, Org., vol. 1, p. 471 ; Leucorrhosa with sterility, MSS. ; Puerperal convulsions, Minton, Raue's Path., p. 902, Hom. Clin., vol. 1, p. 76; Colby, Raue's Pec, 1874, p. 247 ; G. B., N. E. M. G., vol. 11, p. 405 ; Ovarian pain after confinement, J. H. Pat- ton, MSS.; Phlegmasia alba dolens, M., Allg. Hom. Ztg., vol. 108, p. 156; Vitiated milk, Riick. Kl. Erf., vol. 2, p. 412 ; Aphonia, Knickbocker, Raue's Pec, 1873, p. 88 ; Affections of larynx, Lobethal, Piick. Kl. Erf., vol. 3, p. 168 ; Spasms of larynx, Knickbocker, Pane's Rec, 1873, p. 89 ; Spasm of glottis. Smith, N. E. M. G., vol. 8, p. 310; Croup, Guernsey, Raue's Rec, 1871, p. 80; Membranous croup. Frost, Am. Hom. Rev., vol. 5, p. 491 ; Bronchitis and aphonia, Stow, Raue's Pec, 1874, p. 5G1 LACHESIS. 145 ; Bronchial catarrh (5 cases), Boyce, Am, Horn. Rev., vol. 4, p. 415 ; Respiratory affections, Hering, Ruck. Kl. Erf., vol. 3, p. 18 ; Dyspnea, Allg. Horn. Ztg., vol. 107, p. 157 ; Asthma, Hart, Raue's Rec, 1875, p. 118 ; Med.. Inv., vol. 11, p. 225 ; Heriug, Rlick. Kl. Erf., vol. 3, p. 190; Asthmatic cough, Deck, B. J. H., vol. 31, p. 173; Pdiiis ill chest, C Neidhard, MSS. ; Threatened paralysis of lungs, Trinks, Riick. Kl. Erf., vol. 5, p. 762 ; Chest affection, Hering, B. J. H., vol. 2, p. 3(59 ; Lwng affection, Hering, B. J. H., vol. 2, p. 377; Weber, Med. Inv., vol. 5, p. 33 ; Wurmb, Riick. Kl. Erf., vol. 5, p. 822 ; Consumption, Hering, Riick. Kl. Erf., vol. 3, p. 380; Tuberculosis, Wells, Horn. Clin., vol. 4, p. 121 ; ttmith, N. E. M. G., vul. 8, p. 309 ; CAromc pZewro-pTieitmoreia, C Neidhard, MSS. ; Affection of heart. Deck, B. J. H., vol. 31, p. 175 ; Hale, Org , vol. 2, p. 220 ; Stow, Raue's Rec, 1870, p. 197; Cyanosis, Yon Tagen, Raue's Rec, 1871, p. 106; Functional disease of heart, Smith, N. E. M. G., vol. 8, p. 116; Attacks of dyspnoea and palpitation, Gerstel, Allg. Horn. Ztg., vol. 106, p. 99; Affection of mammary gland, Oehme, Riick. Kl. Erf., vol. 5, p. 648 ; Mammary tumor, Oehme, Riick. Kl. Erf , vol. 4, p. 304 ; Ab- scess 0,1 /. side of neck, after scarlatina, W^ells, Am. H. Rev., vol. 4, p. 362 ; Affection of spine, Seward, Horn. Phys., vol. 3, p. 310; Caries of dorsal spine, Wesselhoeft, B. J. H., vol. 22, p. 481; Phlegmonous inflammation of hand, M., Allg. Horn Ztg., vol. 108, p 156 ; Gangrene of hand, Allen, Am. Hom Rev., vol., 4, p. 558 ; Affection of r. hand, Flering, B. J. H., vol. 2, p. 374; Whitlow, Bell, Raue's Rec, 1870, p. 327 ; Panaritium, Kreuss, Stapf, Riick. Kl. Erf., vol. 3, p. 558 ; Onychia, Wood, Org., vol. 2, p. 106; Contraction of psoas muscle after pelvic abscess, Hale, Eaue's Kec, 1874, p. 109 ; Paralysis of legs and chest affection, Wesselhoeft, B. J. H., vol. 22, p. 482; Scicdica, Miller, Raue's Rec, 1875, p. 246; Org., vol. 3, p. 357; Affection of knee, Fielitz, Riick. Kl. Erf, vol. 3, p. 587 ; Varicose veins of knee, Schiissler, Riick. Kl. Erf, vol. 5, p. 860; Pain below knee, J. H, Patton, MSS.; Ulcer of leg, J. C. Morgan, MSS.; Ulcer, with paralysis of I. leg, Baer, Org., vol. 3, p. 103; Syphilitic ulcer on leg, Hafen, Allg. Hom. Ztg., vol. 105, p. 108 ; Gangrene of leg, Allen, Am. Hom. Rev., vol. 4, p. 557 ; Indolent ulcers on foot, W. Story, MSS. ; Affection of second toe of r. foot, B. J. H., vol. 2, p. 376; Pain in joints, 'Riick. Kl. Erf., vol. 5, p. 900 ; Hystefia, B. in D., Riick. Kl. Erf., vol. 2, p. 286 ; Bahrenberg, Allg. Hom. Ztg., vol. 101, p. 134 ; Spasms in meningitis, C. Neidhard, MSS. ; Urannic con- vulsions. Barrows, Times Retros., vol. 2, p. 14; Convulsions (3 cases). Finch, Hom. Clin., vol. 4, p. 30, Raue's Rec, 1871, p. 186; Chorea, Constantine Lippe, MSS.; Epilepsy, C. Mohr, MSS. ; Tietze, Hering, Pulte, Riick. Kl. Erf., vol. 4, p. 577 ; (4 cases) Preston, Baker, Times Retros., vol. 1, p. 123; Friese, Raue's Eec, 1872, p. 228 ; Tetanus, Sircar, Raue's P., p. 890 ; Smith, Eaue's Rec, 1874, p. 264 ; Opisthotonos, Oehme, Allg. Hom. Ztg., vol. 103, p. 207 ; Catalepsy, C. Mohr, MSS. ; Nervousness, Deck, B. J. H.,vol. 31, p. 174; Nervous affection, Bahrenberg, Org., vol. 3, p 90 ; General breakdown after repeated attacks of pneumonia, Kenyon, Am. Hom. Rev., vol. 5, p. 269 ; Neuralgia, Bojanus, Hom. Clin., vol. 3, p. Ill ; Howard, Org., vol. 3, p. Ill; Post-diphtheritic affection, Martin, Org., vol. 2, p. 1 08 ; Incipient paralysis; Sleeplessness, C. Neidhard, MSS ; Intermittent fever, Hering, Riick. Kl. Erf., vol. 4, p. 941; Lippe, Bernreuter, Times Retros., vol. 3, p. 30; Intermittent, with ovarian cd)scess, Linsley, MSS. ; Ague, Walker, Dever, Jennings, Allen's Inter- mittent Fever, p. 160; C. Neidhard, MSS.; J. C. Morgan, MSS.; Typhoid, jSIohr, Trans. Hom. Med. Soc. Pa., 1880, p. 208; Bojanus, Ruck. Kl. Erf., vol. 4, p. 745 ; Boyce, Brewster, Miller, Raue's Rec, 1874, p. 284; Boyce, Med. Inv., vol. 5, p. 5; Hydrophobia, Hering, Riick. Kl. Erf, vol. 4, p. 624; Toothaker, Raue's Rec, 1874, p. 276; Septicemia, result of dissecting wound, Dunham, Dunham's Lec- VOL. VI. — 36. LAOHESIS. 562 tares, vol. 2, p. 247 ; Phlebitis, Dunham, B. J. H., vol. 31, p. 124; (8 cases) Dun- ham A. H. O., vol. 4, p. 110; Rheumatmn, Linsley, Horn. Clin., vol. 1, p. 44; ^mith, Raue's Eec, 1874, p. 254; Hemorrhage in typhoid fever, Guernsey, Hah. M. vol. 6, p. 175 ; Erysipelas, Gross, Kreuss, Riick. Kl. Erf., vol. 4, p. 143; Smith, Kane's Eee., 1874, p. 291; Carbuncle, Hering, Riick. Kl. Erf., vol. 4, p. 183; C. B. Knerr, MSS. ; Dunham, A. H. O., vol. 4, p. Ill ; Eerridge, Times Ketros., vol. 3, p. 30; Traamatic gangrene, J. H. Patton, MSS.; (2 cases) Franklin, Hughes' Pharm., p. 493; B. J. H., vol 27, p. 322; Simon, Riick. Kl. Erf, vol 4, ]). 1027 ; Gangrene, Hiatt, N. A. J. H., vol. 13, p. 493 ; J. C. Morgan, MSS., Gil- christ's Surg., p. 91; Epidemic malignant pustule (8 cases), Dunham, A. H. O., vol. 4, p. 110 ; B. J. H., vol. 31, p. 123 ; Dropsy, Wolf, Gross, Riick. Kl. Erf, vol. 4, p. 349 ; Anasarca, Frost, Am. Hum. Rev., vol. 6, p. 492 ; Syphilis, Hering, Riick. Kl. Erf, vol. 2, p. 123 ; Morgan, Am. H. Rev., vol. 4, p. 410 ; Bedscnxs, Strong, Raue's Rec, 1874, p. 285; Measles, Miller, Raue's Rec, 1873, p. 222, Raue's P., p. 1006; Repercussion of measles, Dunham, A. Hom. Rev., vol. 4, p. 32 ; Malignant scarlatina, Bringham, MSS.; Scarlet fever, P. P.Wells, MSS.; G. B. Saertelle, MSS.; Wells, N. A. J. H., vol. 24, p. 411 ; Gross, Lobethal, Riick. Kl. Erf, vol. 4, p. 58 ; Hughes, B. J. H., vol. 31, p. 125 ; Allen, Am. Hom. Rev., vol. 4, p. 556 ; Skin affection, Ber- rido-e Hom. Phys., vol. 4, p. 288 ; Eruption on arm and abdomen, \V. Story, MSS. ; Itch, Hering, MSS., B. J. H., vol. 2, p. 375; Eczema, Scott, Hah. Mo., vol I, p. 460 ; Pustular eruption, AVesselhoeft, B. J. H , vol. 22, p 486 ; Gross, Hering, Riick. Kl. Erf., vol. 4, p. 243; Herpes zoster, Elb, Allg. Hom. Ztg, vol. 110, (>. 18 ; Boils, abscesses, J. H. Patton, MSS. ; Ulcers, Griesselich, Gross, Ruck. Kl Erf, vol. 4, p. 284; Iiulolent idcers, Smith, Gwynn, Raue's Rec, 1874, p. 295; Hall, Raue's Rec, 1873, p. 247; Antidote to bee sting, Boyce, Raue's Rec, 1870, p. 90; Baugh, Med. Tnves., vol. 6, p. 54; Antidote to Bufo, Weber, Raue's Rec, 1870, p. 91 ; Dog bite, Linsley, MSS. ; Tarantula 6fe, Hardenstein, Hom. Clin., vol. 4, p. 106; Antidote to bite of rattlesnake, Weber, Raue's Rec, 1870, p. 91. ^ Mind. 'Loss of consciousness. 1 1 Weakness of memory ; makes mistakes in writing ; con- fusion as to time. c Great dulness of mind with bodily weakness. ^Typhus. EMind confused and wandering. ^Diphtheria. I B Quick comprehension ; mental activity, with almost pro- phetical perception ; ecstasy ; a kind of trance. I No sooner does one idea occur to him, than a number of others follow in quick succession while he is writing. ■Visions and delirious talk as soon as he shuts eyes; < noon till midnight. BThinks: she is somebody else and in the hands of a stronger power; she is dead, and preparations are made for funeral, or that she is nearly dead and wishes some one would help her off; herself pursued by enemies, or fears medicine is poison ; there are robbers in house and wants to jump out of window; herself under super- human control ; visions real ; he will die. I Imagines he is followed by enemies who are trying to harm him ; attempts to leave room as if frightened by visions behind him. ^Fistula. 5G3 LACHESIS. 1 1 Delirium at night, muttering, drowsy, red face; slow, difficult speech and dropped jaw. ■ Violent delirium especially after sleeping. ^Typhoid. ■ Delirium ; fears she will be damned. ■ Constant delirium which changes rapidly from one sub- ject to another. ^Diphtheria. ■ Delirium from overwatching, overfatigue; loss of fluids; excessive study. ■ iDeKrium tremens, attacks come most in afternoon, or after sleep; loquacious, jumps from subject to subject, cannot bear shirt or neckband to touch throat. ■ Most extraordinary loquacity, making speeches in very select phrases, but jumping off to most heterogeneous subjects ; at same time proud, full of mistrust. ^Mania. ■ Religious monomania, fear of being damned. ■ lOne word often leads into midst of another story. ■ Insane jealousy. ■ His mind is disturbed before the attack. ^Epilepsy. ■ After operation for fistula in ano, complained of his head, particularly pain in 1. temple and occiput ; aching pain in lumbar region; came home from work dizzy, faint and nauseated ; talked incoherently, talked as it were in a strange language; since then quite without mind ; will frequently cry and whine, then laugh in silliest manner; does not sleep at night; sleeps only a minute or two at a time during day ; is often violent, only with difficulty can be kept in bed ; endeavors to climb up bedpost; has an idiotic expression; articulation imper- fect ; tongue lolling about in mouth ; eyes rolling va- cantly ; frequently rises, with great effort and awkward- ness; body when standing bends toward 1., must be supported; drags his feet in walking, direction of steps toward 1.; entirely unable to feed himself; seems in- different to food ; imagines he is followed by enemies who are trying to harm him ; attempts to leave room as if frightened by visions behind him. ^Mental disorder. I I She is tempted to commit suicide. dUania. ■ ■Loquacity; much rapid talking; wants to talk all the