Acts upon the cerebro-spinal system, and more especially upon the pneumogastric. The nerve centers are poisoned, and as a result, prostration, convulsions, and unconsciousness ensue, while from the influence of the pneumogastric we obtain irritable conditions of the throat, larynx, bronchi, and heart, yet not passing into distinct inflammation. As a farther result of the poison, the blood becomes inoculated, decomposition sets in, the fibrine of the blood is destroyed, and we have, as a result, ecchymoses, haemorrhages, asthenic inflammations, abscesses, malignant inflammations, gangrene, pyoemia, and with all, and as a result of all, a general typhoid condition. The chief characteristic of Lachesis is the aggravation of all its symptoms after sleep. Characteristic symptoms.