A strong indication for this remedy is any trouble beginning on the left side of any part of the body, particularly in the throat , whether going over to the right side subsequently, or remaining on the left side. In diphtheria, or any sore throat, where the trouble begins on the left of the throat or tonsils; if we find the soreness, swelling, or diphtheritic patches on both sides of the throat, ascertain which side was attacked first; or if it is almost entirely on the right side, ascertain whether it started on the left side. (Lycop. is just the reverse of the above; Lycop . troubles begin on the right side.) The patient will probably be restless, with very high pulse, great fever, etc. Another characteristic is: where the patient sleeps into an aggravation; as e.g. , in croup; is very well while awake, but as soon as goes to sleep, the croup symptoms appear in great violence; child almost suffocates, and the mother or nurse is consequently really afraid to let him go to sleep. Also in convulsions; patient has none while awake, but as soon as he is asleep they appear. And so with any trouble that is brought on by going to deep at any time, in day or night. In all haemorrhages from the bowels in the typhoid or typhus fever, when in the bottom of the vessel are seen black particles of blood like charred straw ; there may be epistaxis, with bleeding from the mouth and bowels at the same time. Mental.-- Amativeness; affections of the intellect in general. Sadness when wakening in the morning or night (particularly in the morning; no desire at all to mix with the world. Restless and uneasy); does not wish to attend to business, but wants to be off somewhere all the time. Sexual.-- Female : In females who never get well from the change of life--"have never felt well since that time;" may have unnatural unwell periods. During change of life, where she has flashes of heat all day, and cold flashes on retiring at night.